Failure to increase glucose consumption through the pentose-phosphate pathway results in the death of glucose-6-phosphate dehydrogenase gene-deleted mouse embryonic stem cells … S Filosa, A Fico, F Paglialunga, M Balestrieri, A Crooke, P Verde, ... Biochemical Journal 370 (3), 935-943, 2003 | 210 | 2003 |
The role and therapeutic potential of melatonin in age‐related ocular diseases A Crooke, F Huete‐Toral, B Colligris, J Pintor Journal of pineal research 63 (2), e12430, 2017 | 93 | 2017 |
Signs and symptoms of dry eye in keratoconus patients: a pilot study G Carracedo, A Recchioni, N Alejandre-Alba, A Martin-Gil, A Crooke, ... Current Eye Research 40 (11), 1088-1094, 2015 | 81 | 2015 |
Melatonin receptors trigger cAMP production and inhibit chloride movements in nonpigmented ciliary epithelial cells F Huete-Toral, A Crooke, A Martínez-Águila, J Pintor Journal of Pharmacology and Experimental Therapeutics 352 (1), 119-128, 2015 | 65 | 2015 |
Nucleotides in ocular secretions: their role in ocular physiology A Crooke, A Guzmán-Aranguez, A Peral, MKA Abdurrahman, J Pintor Pharmacology & therapeutics 119 (1), 55-73, 2008 | 57 | 2008 |
Dinucleoside polyphosphates in the eye: from physiology to therapeutics A Guzmán-Aranguez, A Crooke, A Peral, CHV Hoyle, J Pintor Progress in retinal and eye research 26 (6), 674-687, 2007 | 57 | 2007 |
Effect of Melatonin and Analogues on Corneal Wound Healing: Involvement of Mt2 Melatonin Receptor A Crooke, A Guzman-Aranguez, A Mediero, P Alarma-Estrany, ... Current Eye Research 40 (1), 56-65, 2015 | 56 | 2015 |
Sympathetic nervous system modulates the ocular hypotensive action of MT2‐melatonin receptors in normotensive rabbits P Alarma‐Estrany, A Crooke, A Mediero, T Peláez, J Pintor Journal of pineal research 45 (4), 468-475, 2008 | 48 | 2008 |
Real‐time PCR quantification of haematopoietic chimerism after transplantation: a comparison between TaqMan and hybridization probes technologies J MARTINEZ‐LOPEZ, A Crooke, S Grande, R Ayala, ... International Journal of Laboratory Hematology 32 (1p1), e17-e25, 2010 | 45 | 2010 |
Silencing of P2Y2 receptors reduces intraocular pressure in New Zealand rabbits A Martin‐Gil, MJP de Lara, A Crooke, C Santano, A Peral, J Pintor British journal of pharmacology 165 (4b), 1163-1172, 2012 | 43 | 2012 |
Corneal re-epithelialization stimulated by diadenosine polyphosphates recruits RhoA/ROCK and ERK1/2 pathways A Mediero, A Guzmán-Aranguez, A Crooke, A Peral, J Pintor Investigative ophthalmology & visual science 49 (11), 4982-4992, 2008 | 43 | 2008 |
Melatonin and its analog 5-methoxycarbonylamino-N-acetyltryptamine potentiate adrenergic receptor-mediated ocular hypotensive effects in rabbits: significance for combination … A Crooke, F Huete-Toral, A Martínez-Águila, A Martín-Gil, J Pintor Journal of Pharmacology and Experimental Therapeutics 346 (1), 138-145, 2013 | 42 | 2013 |
Update in glaucoma medicinal chemistry: emerging evidence for the importance of melatonin analogues A Crooke, B Colligris, J Pintor Current medicinal chemistry 19 (21), 3508-3522, 2012 | 42 | 2012 |
5‐MCA‐NAT does not act through NQO2 to reduce intraocular pressure in New‐Zealand white rabbit P Alarma‐Estrany, A Crooke, J Pintor Journal of pineal research 47 (2), 201-209, 2009 | 42 | 2009 |
Transient silencing of Plasmodium falciparum bifunctional glucose‐6‐phosphate dehydrogenase− 6‐phosphogluconolactonase A Crooke, A Diez, PJ Mason, JM Bautista The FEBS journal 273 (7), 1537-1546, 2006 | 42 | 2006 |
Hypotensive effect of UDP on intraocular pressure in rabbits A Markovskaya, A Crooke, AI Guzmán-Aranguez, A Peral, AU Ziganshin, ... European journal of pharmacology 579 (1-3), 93-97, 2008 | 40 | 2008 |
An update on dry eye disease molecular treatment: advances in drug pipelines B Colligris, A Crooke, F Huete-Toral, J Pintor Expert opinion on pharmacotherapy 15 (10), 1371-1390, 2014 | 39 | 2014 |
Involvement of carbonic anhydrases in the ocular hypotensive effect of melatonin analogue 5‐MCA‐NAT A Crooke, F Huete‐Toral, A Martínez‐Águila, A Martín‐Gil, J Pintor Journal of pineal research 52 (3), 265-270, 2012 | 35 | 2012 |
Ocular disorders and the utility of animal models in the discovery of melatoninergic drugs with therapeutic potential A Crooke, F Huete-Toral, A Martínez-Águila, B Colligris, J Pintor Expert Opinion on Drug Discovery 7 (10), 989-1001, 2012 | 34 | 2012 |
Silencing of P2Y2 receptor delays Ap4A-corneal re-epithelialization process A Crooke, A Mediero, A Guzmán-Aránguez, J Pintor Molecular vision 15, 1169, 2009 | 32 | 2009 |