Comparison of T cell activities mediated by human TCRs and CARs that use the same recognition domains DT Harris, MV Hager, SN Smith, Q Cai, JD Stone, P Kruger, M Lever, ... The Journal of Immunology 200 (3), 1088-1100, 2018 | 153 | 2018 |
Yeast lipin 1 orthologue pah1p regulates vacuole homeostasis and membrane fusion T Sasser, QS Qiu, S Karunakaran, M Padolina, A Reyes, B Flood, S Smith, ... Journal of Biological Chemistry 287 (3), 2221-2236, 2012 | 110 | 2012 |
Changing the peptide specificity of a human T-cell receptor by directed evolution SN Smith, Y Wang, JL Baylon, NK Singh, BM Baker, E Tajkhorshid, ... Nature communications 5 (1), 5223, 2014 | 44 | 2014 |
Residual feed intake of Angus beef cattle divergently selected for feed conversion ratio SN Smith, ME Davis, SC Loerch Livestock Science 132 (1-3), 41-47, 2010 | 36 | 2010 |
NK cells with tissue-resident traits shape response to immunotherapy by inducing adaptive antitumor immunity N Kirchhammer, MP Trefny, M Natoli, D Brücher, SN Smith, F Werner, ... Science translational medicine 14 (653), eabm9043, 2022 | 34 | 2022 |
T cell receptor engineering and analysis using the yeast display platform SN Smith, DT Harris, DM Kranz Yeast Surface Display: Methods, Protocols, and Applications, 95-141, 2015 | 30 | 2015 |
An engineered switch in T cell receptor specificity leads to an unusual but functional binding geometry DT Harris, NK Singh, Q Cai, SN Smith, CW Vander Kooi, E Procko, ... Structure 24 (7), 1142-1154, 2016 | 29 | 2016 |
Engineering t cell receptors SN Smith, DM Kranz US Patent App. 14/417,434, 2015 | 27 | 2015 |
iMATCH: an integrated modular assembly system for therapeutic combination high-capacity adenovirus gene therapy D Brücher, N Kirchhammer, SN Smith, J Schumacher, N Schumacher, ... Molecular Therapy-Methods & Clinical Development 20, 572-586, 2021 | 24 | 2021 |
The SHREAD gene therapy platform for paracrine delivery improves tumor localization and intratumoral effects of a clinical antibody SN Smith, R Schubert, B Simic, D Brücher, M Schmid, N Kirk, PC Freitag, ... Proceedings of the National Academy of Sciences 118 (21), e2017925118, 2021 | 20 | 2021 |
Plasticity in the contribution of T cell receptor variable region residues to binding of peptide–HLA-A2 complexes SN Smith, D Sommermeyer, KH Piepenbrink, SJ Blevins, H Bernhard, ... Journal of molecular biology 425 (22), 4496-4507, 2013 | 19 | 2013 |
Engineered high-affinity human t cell receptors SN Smith, DT Harris, DM Kranz, PD Greenberg, TM Schmitt US Patent 10,344,075, 2019 | 9 | 2019 |
Malignant tissues produce divergent antibody glycosylation of relevance for cancer gene therapy effectiveness D Brücher, V Franc, SN Smith, AJR Heck, A Plückthun MAbs 12 (1), 1792084, 2020 | 8 | 2020 |
Engineered high-affinity human t cell receptors SN Smith, DT Harris, DM Kranz US Patent 10,023,625, 2018 | 7 | 2018 |
Targeted adenovirus-mediated transduction of human T cells in vitro and in vivo PC Freitag, M Kaulfuss, L Flühler, J Mietz, F Weiss, D Brücher, J Kolibius, ... Molecular Therapy-Methods & Clinical Development 29, 120-132, 2023 | 4 | 2023 |
CRISPR-clear imaging of melanin-rich B16-derived solid tumors R Schubert, T Bae, B Simic, SN Smith, SH Park, G Nagy-Davidescu, ... Communications Biology 6 (1), 370, 2023 | 2 | 2023 |
Successful IL-12 cancer immunotherapy requires NK cell-derived CCL5 for anti-tumor DC-T cell crosstalk N Kirchhammer, MP Trefny, M Natoli bioRxiv, 2021 | 2 | 2021 |
Engineering t cell receptors SN Smith, DM Kranz US Patent 11,384,133, 2022 | 1 | 2022 |
Engineered high-affinity human t cell receptors SN Smith, DT Harris, DM Kranz US Patent App. 17/586,652, 2022 | | 2022 |
Adaptive anti-tumor immunity is orchestrated by a population of CCL5-producing tissue-resident NK cells N Kirchhammer, MP Trefny, M Natoli, D Brücher, SN Smith, F Werner, ... bioRxiv, 2021.05. 27.445981, 2021 | | 2021 |