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Javier Ganz
Javier Ganz
Harvard Medical School / Boston Children's Hospital
Verified email at childrens.harvard.edu
Title
Cited by
Cited by
Year
Intersection of diverse neuronal genomes and neuropsychiatric disease: The Brain Somatic Mosaicism Network
MJ McConnell, JV Moran, A Abyzov, S Akbarian, T Bae, I Cortes-Ciriano, ...
Science 356 (6336), eaal1641, 2017
2432017
Mesenchymal stem cell transplantation promotes neurogenesis and ameliorates autism related behaviors in BTBR mice
H Segal‐Gavish, G Karvat, N Barak, R Barzilay, J Ganz, L Edry, I Aharony, ...
Autism Research 9 (1), 17-32, 2016
922016
Landmarks of human embryonic development inscribed in somatic mutations
S Bizzotto, Y Dou, J Ganz, RN Doan, M Kwon, CL Bohrson, SN Kim, ...
Science 371 (6535), 1249-1253, 2021
772021
Cell replacement therapy for Parkinson’s disease: how close are we to the clinic?
J Ganz, N Lev, E Melamed, D Offen
Expert review of neurotherapeutics 11 (9), 1325-1339, 2011
482011
A novel specific PERK activator reduces toxicity and extends survival in Huntington's disease models
J Ganz, T Shacham, M Kramer, M Shenkman, H Eiger, N Weinberg, ...
Scientific reports 10 (1), 6875, 2020
432020
Astrocyte-like cells derived from human oral mucosa stem cells provide neuroprotection in vitro and in vivo
J Ganz, I Arie, T Ben-Zur, M Dadon-Nachum, S Pour, S Araidy, S Pitaru, ...
Stem cells translational medicine 3 (3), 375-386, 2014
422014
Harnessing neurogenesis for the possible treatment of Parkinson's disease
O Lamm, J Ganz, E Melamed, D Offen
Journal of Comparative Neurology 522 (12), 2817-2830, 2014
362014
Comprehensive identification of somatic nucleotide variants in human brain tissue
Y Wang, T Bae, J Thorpe, MA Sherman, AG Jones, S Cho, K Daily, Y Dou, ...
Genome biology 22, 1-32, 2021
342021
Single-cell genome sequencing of human neurons identifies somatic point mutation and indel enrichment in regulatory elements
LJ Luquette, MB Miller, Z Zhou, CL Bohrson, Y Zhao, H Jin, D Gulhan, ...
Nature genetics 54 (10), 1564-1571, 2022
332022
Analysis of somatic mutations in 131 human brains reveals aging-associated hypermutability
T Bae, L Fasching, Y Wang, JH Shin, M Suvakov, Y Jang, S Norton, ...
Science 377 (6605), 511-517, 2022
332022
Implantation of 3D constructs embedded with oral mucosa-derived cells induces functional recovery in rats with complete spinal cord transection
J Ganz, E Shor, S Guo, A Sheinin, I Arie, I Michaelevski, S Pitaru, D Offen, ...
Frontiers in Neuroscience 11, 589, 2017
332017
Rates and patterns of clonal oncogenic mutations in the normal human brain
J Ganz, EA Maury, B Becerra, S Bizzotto, RN Doan, CJ Kenny, T Shin, ...
Cancer discovery 12 (1), 172-185, 2022
262022
Dopaminergic-like neurons derived from oral mucosa stem cells by developmental cues improve symptoms in the hemi-parkinsonian rat model
J Ganz, I Arie, S Buch, TB Zur, Y Barhum, S Pour, S Araidy, S Pitaru, ...
PLoS One 9 (6), e100445, 2014
252014
Mesenchymal stem cells protect from sub-chronic phencyclidine insult in vivo and counteract changes in astrocyte gene expression in vitro
R Barzilay, J Ganz, O Sadan, T Ben-Zur, Z Bren, N Hinden, M Taler, N Lev, ...
European Neuropsychopharmacology 23 (9), 1115-1123, 2013
172013
MIPP-Seq: ultra-sensitive rapid detection and validation of low-frequency mosaic mutations
RN Doan, MB Miller, SN Kim, RE Rodin, J Ganz, S Bizzotto, KS Morillo, ...
BMC Medical Genomics 14, 1-13, 2021
162021
Brain Somatic Mosaicism Network
MJ McConnell, JV Moran, A Abyzov, S Akbarian, T Bae, I Cortes-Ciriano, ...
Intersection of diverse neuronal genomes and neuropsychiatric disease: The …, 2017
72017
Schizophrenia-associated somatic copy-number variants from 12,834 cases reveal recurrent NRXN1 and ABCB11 disruptions
EA Maury, MA Sherman, G Genovese, TG Gilgenast, T Kamath, SJ Burris, ...
Cell Genomics 3 (8), 2023
42023
Contrasting patterns of somatic mutations in neurons and glia reveal differential predisposition to disease in the aging human brain
J Ganz, LJ Luquette, S Bizzotto, CL Bohrson, H Jin, MB Miller, Z Zhou, ...
bioRxiv, 2023
32023
Perk inhibitors and uses thereof in treating diseases associated with aggregation-prone proteins
GZ Lederkremer, J Leitman, H Eiger, D Offen, J Ganz, M Portnoy
US Patent 10,723,706, 2020
22020
Somatic mutation cell lineage analysis reveals progressive clonal determination in human embryo
S Bizzotto, J Ganz, Y Dou, RN Doan, E Maury, M Kwon, T Bae, A Abyzov, ...
EUROPEAN JOURNAL OF HUMAN GENETICS 27, 1154-1154, 2019
12019
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