| Fisetin is a senotherapeutic that extends health and lifespan MJ Yousefzadeh, YI Zhu, SJ McGowan, L Angelini, ... EBioMedicine 36, 18-28, 2018 | 673 | 2018 |
| An aged immune system drives senescence and ageing of solid organs MJ Yousefzadeh, RR Flores, YI Zhu, ZC Schmiechen, RW Brooks, ... Nature 594 (7861), 100-105, 2021 | 440 | 2021 |
| Essential roles for polymerase θ-mediated end joining in the repair of chromosome breaks DW Wyatt, W Feng, MP Conlin, MJ Yousefzadeh, SA Roberts, ... Molecular cell 63 (4), 662-673, 2016 | 287 | 2016 |
| Mechanism of suppression of chromosomal instability by DNA polymerase POLQ MJ Yousefzadeh, DW Wyatt, K Takata, Y Mu, SC Hensley, J Tomida, ... PLoS genetics 10 (10), e1004654, 2014 | 270 | 2014 |
| DNA damage—how and why we age? M Yousefzadeh, C Henpita, R Vyas, C Soto-Palma, P Robbins, ... Elife 10, e62852, 2021 | 251 | 2021 |
| Senolytics reduce coronavirus-related mortality in old mice CD Camell, MJ Yousefzadeh, Y Zhu, LGPL Prata, MA Huggins, M Pierson, ... Science 373 (6552), eabe4832, 2021 | 212 | 2021 |
| Tissue specificity of senescent cell accumulation during physiologic and accelerated aging of mice MJ Yousefzadeh, J Zhao, C Bukata, EA Wade, SJ McGowan, LA Angelini, ... Aging cell 19 (3), e13094, 2020 | 202 | 2020 |
| Cellular senescence: a key therapeutic target in aging and diseases L Zhang, LE Pitcher, MJ Yousefzadeh, LJ Niedernhofer, PD Robbins, ... The Journal of Clinical Investigation 132 (15), 2022 | 139 | 2022 |
| Senolytic combination of dasatinib and quercetin alleviates intestinal senescence and inflammation and modulates the gut microbiome in aged mice TD Saccon, R Nagpal, H Yadav, MB Cavalcante, ADC Nunes, ... The Journals of Gerontology: Series A 76 (11), 1895-1905, 2021 | 135 | 2021 |
| Spontaneous DNA damage to the nuclear genome promotes senescence, redox imbalance and aging AR Robinson, MJ Yousefzadeh, TA Rozgaja, J Wang, X Li, JS Tilstra, ... Redox biology 17, 259-273, 2018 | 112 | 2018 |
| DNA polymerase POLQ and cellular defense against DNA damage MJ Yousefzadeh, RD Wood DNA repair 12 (1), 1-9, 2013 | 112 | 2013 |
| Circulating levels of monocyte chemoattractant protein‐1 as a potential measure of biological age in mice and frailty in humans MJ Yousefzadeh, MJ Schafer, N Noren Hooten, EJ Atkinson, MK Evans, ... Aging cell 17 (2), e12706, 2018 | 101 | 2018 |
| ATM is a key driver of NF-κB-dependent DNA-damage-induced senescence, stem cell dysfunction and aging J Zhao, L Zhang, A Lu, Y Han, D Colangelo, C Bukata, A Scibetta, ... Aging (Albany NY) 12 (6), 4688, 2020 | 70 | 2020 |
| REV7 is essential for DNA damage tolerance via two REV3L binding sites in mammalian DNA polymerase ζ J Tomida, K Takata, SS Lange, AC Schibler, MJ Yousefzadeh, S Bhetawal, ... Nucleic acids research 43 (2), 1000-1011, 2015 | 66 | 2015 |
| Exercise reduces circulating biomarkers of cellular senescence in humans DA Englund, AE Sakamoto, CM Fritsche, AA Heeren, X Zhang, ... Aging Cell 20 (7), e13415, 2021 | 53 | 2021 |
| Heterochronic parabiosis regulates the extent of cellular senescence in multiple tissues MJ Yousefzadeh, JE Wilkinson, B Hughes, N Gadela, WC Ladiges, N Vo, ... Geroscience 42, 951-961, 2020 | 52 | 2020 |
| The expression ratio of Map7/B2M is prognostic for survival in patients with stage II colon cancer C Blum, A Graham, M Yousefzadeh, J Shrout, K Benjamin, M Krishna, ... International journal of oncology 33 (3), 579-584, 2008 | 46 | 2008 |
| β2microglobulin mRNA expression levels are prognostic for lymph node metastasis in colorectal cancer patients J Shrout, M Yousefzadeh, A Dodd, K Kirven, C Blum, A Graham, ... British journal of cancer 98 (12), 1999-2005, 2008 | 45 | 2008 |
| Mouse models of accelerated cellular senescence MJ Yousefzadeh, KI Melos, L Angelini, CE Burd, PD Robbins, ... Cellular Senescence: Methods and Protocols, 203-230, 2019 | 39 | 2019 |
| Novel small molecule inhibition of IKK/NF‐κB activation reduces markers of senescence and improves healthspan in mouse models of aging L Zhang, J Zhao, X Mu, SJ McGowan, L Angelini, RD O'Kelly, ... Aging Cell 20 (12), e13486, 2021 | 37 | 2021 |
