| Insights into the molecular architecture and histone H3-H4 deposition mechanism of yeast Chromatin assembly factor 1 PV Sauer, J Timm, D Liu, D Sitbon, E Boeri-Erba, C Velours, N Mücke, ... Elife 6, e23474, 2017 | 61 | 2017 |
| Drug design strategies to avoid resistance in direct-acting antivirals and beyond AN Matthew, F Leidner, GJ Lockbaum, M Henes, J Zephyr, S Hou, ... Chemical reviews 121 (6), 3238-3270, 2021 | 43 | 2021 |
| Pan-3C protease inhibitor rupintrivir binds SARS-CoV-2 main protease in a unique binding mode GJ Lockbaum, M Henes, JM Lee, J Timm, EA Nalivaika, PR Thompson, ... Biochemistry 60 (39), 2925-2931, 2021 | 23 | 2021 |
| Structural characterization of acidic M17 leucine aminopeptidases from the TriTryps and evaluation of their role in nutrient starvation in Trypanosoma brucei J Timm, M Valente, D García-Caballero, KS Wilson, ... msphere 2 (4), 10.1128/msphere. 00226-17, 2017 | 21 | 2017 |
| Structural and Kinetic Characterization of Thymidine Kinase from Leishmania major J Timm, C Bosch-Navarrete, E Recio, JE Nettleship, H Rada, ... PLoS neglected tropical diseases 9 (5), e0003781, 2015 | 20 | 2015 |
| Revealing the structural plasticity of SARS-CoV-2 nsp7 and nsp8 using structural proteomics VV Courouble, SK Dey, R Yadav, J Timm, JJEK Harrison, FX Ruiz, ... Journal of the American Society for Mass Spectrometry 32 (7), 1618-1630, 2021 | 18 | 2021 |
| The carbon monoxide dehydrogenase accessory protein CooJ is a histidine-rich multidomain dimer containing an unexpected Ni (II)-binding site M Alfano, J Pérard, P Carpentier, C Basset, B Zambelli, J Timm, S Crouzy, ... Journal of Biological Chemistry 294 (19), 7601-7614, 2019 | 18 | 2019 |
| The CO dehydrogenase accessory protein CooT is a novel nickel-binding protein J Timm, C Brochier-Armanet, J Perard, B Zambelli, ... Metallomics 9 (5), 575-583, 2017 | 17 | 2017 |
| Avoiding drug resistance by substrate envelope-guided design: Toward potent and robust HCV NS3/4A protease inhibitors AN Matthew, J Zephyr, D Nageswara Rao, M Henes, W Kamran, ... MBio 11 (2), 10.1128/mbio. 00172-20, 2020 | 16 | 2020 |
| Tying down the arm in Bacillus dUTPase: structure and mechanism J García-Nafría, J Timm, C Harrison, JP Turkenburg, KS Wilson Acta Crystallographica Section D: Biological Crystallography 69 (8), 1367-1380, 2013 | 16 | 2013 |
| Cell cycle regulation and novel structural features of thymidine kinase, an essential enzyme in Trypanosoma brucei M Valente, J Timm, VM Castillo‐Acosta, LM Ruiz‐Pérez, T Balzarini, ... Molecular microbiology 102 (3), 365-385, 2016 | 13 | 2016 |
| Biochemical and structural insights into SARS-CoV-2 polyprotein processing by Mpro R Yadav, VV Courouble, SK Dey, JJEK Harrison, J Timm, JB Hopkins, ... Science Advances 8 (49), eadd2191, 2022 | 10 | 2022 |
| Molecular and structural mechanism of pan-genotypic HCV NS3/4A protease inhibition by glecaprevir J Timm, K Kosovrasti, M Henes, F Leidner, S Hou, A Ali, N Kurt Yilmaz, ... ACS chemical biology 15 (2), 342-352, 2019 | 9 | 2019 |
| Design of a minimal di-nickel hydrogenase peptide J Timm, DH Pike, JA Mancini, AM Tyryshkin, S Poudel, JA Siess, ... Science Advances 9 (10), eabq1990, 2023 | 7 | 2023 |
| Structures of adenosine kinase from Trypanosoma brucei brucei J Timm, D González-Pacanowska, KS Wilson Acta Crystallographica Section F: Structural Biology Communications 70 (1 …, 2014 | 7 | 2014 |
| Deciphering the molecular mechanism of HCV protease inhibitor Fluorination as a general approach to avoid drug resistance J Zephyr, DN Rao, SV Vo, M Henes, K Kosovrasti, AN Matthew, ... Journal of molecular biology 434 (9), 167503, 2022 | 6 | 2022 |
| Resolving the dynamic motions of SARS-CoV-2 nsp7 and nsp8 proteins using structural proteomics VV Courouble, SK Dey, R Yadav, J Timm, JJEK Harrison, FX Ruiz, ... bioRxiv, 2021 | 6 | 2021 |
| Avoiding drug resistance by substrate envelope-guided design: toward potent and robust HCV NS3/4A protease inhibitors. mBio 11 (2): e00172-20 AN Matthew, J Zephyr, D Nageswara Rao, M Henes, W Kamran, ... | 5 | 2020 |
| Expanding our knowledge of the SARS-CoV-2 polyproteins: Structural and biochemical insights into the viral processing R Yadav, VV Courouble, SK Dey, JJEK Harrison, J Timm, JB Hopkins, ... Biophysical Journal 123 (3), 53a-54a, 2024 | | 2024 |
| A minimal catalytic di-nickel peptide capable of sustained hydrogen evolution and methods of use thereof J Timm, PG Falkowski, V Nanda, AM Tyryshkin, S Poudel, JA Mancini, ... US Patent App. 18/047,822, 2023 | | 2023 |
