| TAK1 is a ubiquitin-dependent kinase of MKK and IKK C Wang, L Deng, M Hong, GR Akkaraju, J Inoue, ZJ Chen Nature 412 (6844), 346-351, 2001 | 2668 | 2001 |
| Chemical genetics strategy identifies an HCV NS5A inhibitor with a potent clinical effect M Gao, RE Nettles, M Belema, LB Snyder, VN Nguyen, RA Fridell, ... Nature 465 (7294), 96-100, 2010 | 1130 | 2010 |
| Regulation of interferon regulatory factor-3 by the hepatitis C virus serine protease E Foy, K Li, C Wang, R Sumpter Jr, M Ikeda, SM Lemon, M Gale Jr Science 300 (5622), 1145-1148, 2003 | 1097 | 2003 |
| Control of antiviral defenses through hepatitis C virus disruption of retinoic acid-inducible gene-I signaling E Foy, K Li, R Sumpter Jr, YM Loo, CL Johnson, C Wang, PM Fish, ... Proceedings of the National Academy of Sciences 102 (8), 2986-2991, 2005 | 717 | 2005 |
| Disruption of hepatitis C virus RNA replication through inhibition of host protein geranylgeranylation J Ye, C Wang, R Sumpter Jr, MS Brown, JL Goldstein, M Gale Jr Proceedings of the National Academy of Sciences 100 (26), 15865-15870, 2003 | 448 | 2003 |
| Identification of FBL2 as a geranylgeranylated cellular protein required for hepatitis C virus RNA replication C Wang, M Gale, BC Keller, H Huang, MS Brown, JL Goldstein, J Ye Molecular cell 18 (4), 425-434, 2005 | 363 | 2005 |
| Resistance Analysis of the Hepatitis C Virus NS5A Inhibitor BMS-790052 in an In Vitro Replicon System RA Fridell, D Qiu, C Wang, L Valera, M Gao Antimicrobial agents and chemotherapy 54 (9), 3641-3650, 2010 | 352 | 2010 |
| Alpha interferon induces distinct translational control programs to suppress hepatitis C virus RNA replication C Wang, J Pflugheber, R Sumpter Jr, DL Sodora, D Hui, GC Sen, ... Journal of virology 77 (7), 3898-3912, 2003 | 297 | 2003 |
| Genotypic and phenotypic analysis of variants resistant to hepatitis C virus nonstructural protein 5A replication complex inhibitor BMS‐790052 in humans: in vitro and in vivo … RA Fridell, C Wang, JH Sun, DR O'Boyle, P Nower, L Valera, D Qiu, ... Hepatology 54 (6), 1924-1935, 2011 | 247 | 2011 |
| Regulation of PKR and IRF-1 during hepatitis C virus RNA replication J Pflugheber, B Fredericksen, R Sumpter Jr, C Wang, F Ware, DL Sodora, ... Proceedings of the National Academy of Sciences 99 (7), 4650-4655, 2002 | 234 | 2002 |
| Distinct functions of NS5A in hepatitis C virus RNA replication uncovered by studies with the NS5A inhibitor BMS-790052 RA Fridell, D Qiu, L Valera, C Wang, RE Rose, M Gao Journal of virology 85 (14), 7312-7320, 2011 | 174 | 2011 |
| Resistance analysis of hepatitis C virus genotype 1 prior treatment null responders receiving daclatasvir and asunaprevir F McPhee, D Hernandez, F Yu, J Ueland, A Monikowski, A Carifa, P Falk, ... Hepatology 58 (3), 902-911, 2013 | 152 | 2013 |
| Persistence of resistant variants in hepatitis C virus-infected patients treated with the NS5A replication complex inhibitor daclatasvir C Wang, JH Sun, DR O'Boyle, P Nower, L Valera, S Roberts, RA Fridell, ... Antimicrobial agents and chemotherapy 57 (5), 2054-2065, 2013 | 113 | 2013 |
| Viral evolution and interferon resistance of hepatitis C virus RNA replication in a cell culture model R Sumpter Jr, C Wang, E Foy, YM Loo, M Gale Jr Journal of virology 78 (21), 11591-11604, 2004 | 103 | 2004 |
| Activation of the Interferon-β Promoter During Hepatitis C Virus RNA Replication B Fredericksen, GR Akkaraju, E Foy, C Wang, J Pflugheber, ZJ Chen, ... Viral immunology 15 (1), 29-40, 2002 | 83 | 2002 |
| Discovery and development of hepatitis C virus NS5A replication complex inhibitors M Belema, OD Lopez, JA Bender, JL Romine, DR St. Laurent, ... Journal of medicinal chemistry 57 (5), 1643-1672, 2014 | 78 | 2014 |
| Comparison of daclatasvir resistance barriers on NS5A from hepatitis C virus genotypes 1 to 6: implications for cross-genotype activity C Wang, L Jia, DR O'Boyle, JH Sun, K Rigat, L Valera, P Nower, X Huang, ... Antimicrobial agents and chemotherapy 58 (9), 5155-5163, 2014 | 76 | 2014 |
| Hepatitis C virus RNA elimination and development of resistance in replicon cells treated with BMS-790052 C Wang, H Huang, L Valera, JH Sun, DR O'Boyle, PT Nower, L Jia, D Qiu, ... Antimicrobial agents and chemotherapy 56 (3), 1350-1358, 2012 | 67 | 2012 |
| In Vitro Activity of BMS-790052 on Hepatitis C Virus Genotype 4 NS5A C Wang, L Jia, H Huang, D Qiu, L Valera, X Huang, JH Sun, PT Nower, ... Antimicrobial Agents and Chemotherapy 56 (3), 1588-1590, 2012 | 65 | 2012 |
| In Vitro Activity of Daclatasvir on Hepatitis C Virus Genotype 3 NS5A C Wang, L Valera, L Jia, MJ Kirk, M Gao, RA Fridell Antimicrobial agents and chemotherapy 57 (1), 611-613, 2013 | 64 | 2013 |
