Doc2b Is a High-Affinity Ca2+ Sensor for Spontaneous Neurotransmitter Release AJ Groffen, S Martens, RD Arazola, LN Cornelisse, N Lozovaya, ... Science 327 (5973), 1614-1618, 2010 | 351 | 2010 |
Agrin is a major heparan sulfate proteoglycan in the human glomerular basement membrane AJ Groffen, MA Ruegg, H Dijkman, TJ Van De Velden, CA Buskens, ... Journal of Histochemistry & Cytochemistry 46 (1), 19-27, 1998 | 237 | 1998 |
Exonic deletions in AUTS2 cause a syndromic form of intellectual disability and suggest a critical role for the C terminus G Beunders, E Voorhoeve, C Golzio, LM Pardo, JA Rosenfeld, ... The American Journal of Human Genetics 92 (2), 210-220, 2013 | 176 | 2013 |
DOC2A and DOC2B are sensors for neuronal activity with unique calcium‐dependent and kinetic properties AJA Groffen, R Friedrich, EC Brian, U Ashery, M Verhage Journal of neurochemistry 97 (3), 818-833, 2006 | 123 | 2006 |
Recent insights into the structure and functions of heparan sulfate proteoglycans in the human glomerular basement membrane AJA Groffen, JH Veerkamp, LAH Monnens, LPWJ Van Den Heuvel Nephrology Dialysis Transplantation 14 (9), 2119-2129, 1999 | 118 | 1999 |
Primary structure and high expression of human agrin in basement membranes of adult lung and kidney AJA Groffen, CAF Buskens, TH Van Kuppevelt, JH Veerkamp, ... European journal of biochemistry 254 (1), 123-128, 1998 | 102 | 1998 |
Differential expression of agrin in renal basement membranes as revealed by domain-specific antibodies CJI Raats, MAH Bakker, W Hoch, WPM Tamboer, AJA Groffen, ... Journal of Biological Chemistry 273 (28), 17832-17838, 1998 | 100 | 1998 |
Multiple Ca2+ sensors in secretion: teammates, competitors or autocrats? AM Walter, AJ Groffen, JB Sørensen, M Verhage Trends in neurosciences 34 (9), 487-497, 2011 | 81 | 2011 |
DOC2B acts as a calcium switch and enhances vesicle fusion R Friedrich, AJ Groffen, E Connell, JRT Van Weering, O Gutman, YI Henis, ... Journal of Neuroscience 28 (27), 6794-6806, 2008 | 71 | 2008 |
Two distinct genes drive expression of seven tomosyn isoforms in the mammalian brain, sharing a conserved structure with a unique variable domain AJA Groffen, L Jacobsen, D Schut, M Verhage Journal of neurochemistry 92 (3), 554-568, 2005 | 69 | 2005 |
Decreased glomerular expression of agrin in diabetic nephropathy and podocytes, cultured in high glucose medium BA Yard, S Kahlert, R Engelleiter, S Resch, R Waldherr, AJ Groffen, ... Experimental nephrology 9 (3), 214-222, 2001 | 66 | 2001 |
Ca2+-induced recruitment of the secretory vesicle protein DOC2B to the target membrane AJA Groffen, EC Brian, JJ Dudok, J Kampmeijer, RF Toonen, M Verhage Journal of Biological Chemistry 279 (22), 23740-23747, 2004 | 63 | 2004 |
Genetic and phenotypic heterogeneity in sporadic and familial forms of paroxysmal dyskinesia AJA Groffen, T Klapwijk, AF van Rootselaar, JL Groen, MAJ Tijssen Journal of neurology 260, 93-99, 2013 | 60 | 2013 |
Doc2b is a key effector of insulin secretion and skeletal muscle insulin sensitivity L Ramalingam, E Oh, SM Yoder, JT Brozinick, MA Kalwat, AJ Groffen, ... Diabetes 61 (10), 2424-2432, 2012 | 51 | 2012 |
Characterization of baculovirus insecticides expressing tailored Bacillus thuringiensis CryIA (b) crystal proteins JWM Martens, M Knoester, F Weijts, SJA Groffen, Z Hu, D Bosch, JM Vlak Journal of Invertebrate Pathology 66 (3), 249-257, 1995 | 51 | 1995 |
Identification of a Dutch founder mutation in MUSK causing fetal akinesia deformation sequence MB Tan-Sindhunata, IB Mathijssen, M Smit, F Baas, JI De Vries, ... European Journal of Human Genetics 23 (9), 1151-1157, 2015 | 49 | 2015 |
DOC2 isoforms play dual roles in insulin secretion and insulin-stimulated glucose uptake J Li, J Cantley, JG Burchfield, CC Meoli, J Stöckli, PT Whitworth, H Pant, ... Diabetologia 57, 2173-2182, 2014 | 46 | 2014 |
TRIM3 regulates the motility of the kinesin motor protein KIF21B D Labonté, E Thies, Y Pechmann, AJ Groffen, M Verhage, AB Smit, ... PloS one 8 (9), e75603, 2013 | 42 | 2013 |
Evidence for the existence of multiple heparan sulfate proteoglycans in the human glomerular basement membrane and mesangial matrix AJA Groffen, FWH Hop, K Trygovason, H Dijkman, KJM Assmann, ... European journal of biochemistry 247 (1), 175-182, 1997 | 39 | 1997 |
Direct quantitative detection of Doc2b-induced hemifusion in optically trapped membranes I Brouwer, A Giniatullina, N Laurens, JRT Van Weering, D Bald, ... Nature Communications 6 (1), 8387, 2015 | 38 | 2015 |