| Flavonoids induce apoptosis in human leukemia U937 cells through caspase-and caspase-calpain-dependent pathways A Monasterio, MC Urdaci, IV Pinchuk, N Lopez-Moratalla, ... Nutrition and cancer 50 (1), 90-100, 2004 | 172 | 2004 |
| Flavonoids inhibit hypoxia-induced vascular endothelial growth factor expression by a HIF-1 independent mechanism E Ansó, A Zuazo, M Irigoyen, MC Urdaci, A Rouzaut, JJ Martínez-Irujo Biochemical pharmacology 79 (11), 1600-1609, 2010 | 107 | 2010 |
| A checkerboard method to evaluate interactions between drugs JJ Martinez-Irujo, ML Villahermosa, E Alberdi, E Santiago Biochemical pharmacology 51 (5), 635-644, 1996 | 95 | 1996 |
| Endoplasmic reticulum stress-inducing drugs sensitize glioma cells to temozolomide through downregulation of MGMT, MPG, and Rad51 E Xipell, T Aragón, N Martínez-Velez, B Vera, MA Idoate, JJ Martínez-Irujo, ... Neuro-oncology 18 (8), 1109-1119, 2016 | 67 | 2016 |
| Hypoxia alters the adhesive properties of lymphatic endothelial cells. A transcriptional and functional study M Irigoyen, E Ansó, E Martinez, M Garayoa, JJ Martinez-Irujo, A Rouzaut Biochimica et Biophysica Acta (BBA)-Molecular Cell Research 1773 (6), 880-890, 2007 | 66 | 2007 |
| Salinomycin induced ROS results in abortive autophagy and leads to regulated necrosis in glioblastoma E Xipell, M Gonzalez-Huarriz, JJM de Irujo, A García-Garzón, FF Lang, ... Oncotarget 7 (21), 30626, 2016 | 60 | 2016 |
| Indoles and pyridazino [4, 5-b] indoles as nonnucleoside analog inhibitors of HIV-1 reverse transcriptase M Font, A Monge, A Cuartero, A Elorriaga, JJ Martínez-Irujo, E Alberdi, ... European journal of medicinal chemistry 30 (12), 963-971, 1995 | 59 | 1995 |
| Analysis of the combined effect of two linear inhibitors on a single enzyme JJ MARTINEZ-IRUJO, ML VILLAHERMOSA, J MERCAPIDE, ... Biochemical Journal 329 (3), 689-698, 1998 | 46 | 1998 |
| Two ellagitannins from the leaves of Terminalia triflora with inhibitory activity on HIV‐1 reverse transcriptase V Martino, J Morales, JJ Martínez‐Irujo, M Font, A Monge, J Coussio Phytotherapy Research: An International Journal Devoted to Pharmacological …, 2004 | 45 | 2004 |
| Unfolded protein response induced by Brefeldin A increases collagen type I levels in hepatic stellate cells through an IRE1α, p38 MAPK and Smad-dependent pathway MR de Galarreta, A Navarro, E Ansorena, AG Garzón, T Mòdol, ... Biochimica et Biophysica Acta (BBA)-Molecular Cell Research 1863 (8), 2115-2123, 2016 | 41 | 2016 |
| TGFβ-induced protein mediates lymphatic endothelial cell adhesion to the extracellular matrix under low oxygen conditions M Irigoyen, E Ansó, E Salvo, JD De Las Herrerias, JJ Martinez-Irujo, ... Cellular and Molecular Life Sciences 65, 2244-2255, 2008 | 41 | 2008 |
| Fibronectin peptides as potential regulators of hepatic fibrosis through apoptosis of hepatic stellate cells T Mòdol, N Brice, M Ruiz de Galarreta, A Garcia Garzon, MJ Iraburu, ... Journal of cellular physiology 230 (3), 546-553, 2015 | 39 | 2015 |
| NADPH oxidase 5 promotes proliferation and fibrosis in human hepatic stellate cells A Andueza, N Garde, A García-Garzón, E Ansorena, MJ López-Zabalza, ... Free Radical Biology and Medicine 126, 15-26, 2018 | 38 | 2018 |
| Non-nucleoside inhibitors of HIV-1 reverse transcriptase inhibit phosphorolysis and resensitize the 3′-azido-3′-deoxythymidine (AZT)-resistant polymerase to AZT-5′-triphosphate L Odriozola, C Cruchaga, M Andréola, V Dollé, CH Nguyen, ... Journal of Biological Chemistry 278 (43), 42710-42716, 2003 | 38 | 2003 |
| Contribution of phosphodiesterase isoenzymes and cyclic nucleotide efflux to the regulation of cyclic GMP levels in aortic smooth muscle cells J Mercapide, E Santiago, E Alberdi, JJ Martinez–Irujo Biochemical pharmacology 58 (10), 1675-1683, 1999 | 37 | 1999 |
| Recurrent exposure to nicotine differentiates human bronchial epithelial cells via epidermal growth factor receptor activation E Martínez-García, M Irigoyen, E Ansó, JJ Martínez-Irujo, A Rouzaut Toxicology and applied pharmacology 228 (3), 334-342, 2008 | 34 | 2008 |
| Factors affecting the dimerization of the p66 form of HIV‐1 reverse transcriptase JF Cabodevilla, L Odriozola, E Santiago, JJ Martínez‐Irujo European Journal of Biochemistry 268 (5), 1163-1172, 2001 | 32 | 2001 |
| Argentine plant extracts active against polymerase and ribonuclease H activities of HIV‐1 reverse transcriptase O Hnatyszyn, A Broussalis, G Herrera, L Muschietti, J Coussio, V Martino, ... Phytotherapy Research 13 (3), 206-209, 1999 | 32 | 1999 |
| Synergistic inhibition of HIV-1 reverse transcriptase by combinations of chain-terminating nucleotides ML Villahermosa, JJ Martinez-Irujo, F Cabodevilla, E Santiago Biochemistry 36 (43), 13223-13231, 1997 | 32 | 1997 |
| Inhibition of phosphorolysis catalyzed by HIV-1 reverse transcriptase is responsible for the synergy found in combinations of 3 ‘-azido-3 ‘-deoxythymidine with nonnucleoside … C Cruchaga, L Odriozola, M Andréola, L Tarrago-Litvak, JJ Martínez-Irujo Biochemistry 44 (9), 3535-3546, 2005 | 30 | 2005 |
Ana RouzautProfessor of Biochemistry, ResearcherVerified email at unav.es
