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Richard John Ward
Richard John Ward
Dirección de correo verificada de fmrp.usp.br
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Phospholipase A2—a structural review
RK Arni, RJ Ward
Toxicon 34 (8), 827-841, 1996
5311996
Structure of a calcium-independent phospholipase-like myotoxic protein from Bothrops asper venom
RK Arni, RJ Ward, JM Gutiérrez, A Tulinsky
Acta Crystallographica Section D: Biological Crystallography 51 (3), 311-317, 1995
1491995
Structural basis for glucose tolerance in GH1 β-glucosidases
PO de Giuseppe, TACB Souza, FHM Souza, LM Zanphorlin, CB Machado, ...
Acta Crystallographica Section D: Biological Crystallography 70 (6), 1631-1639, 2014
1422014
Active-site mutagenesis of a Lys49-phospholipase A2: biological and membrane-disrupting activities in the absence of catalysis
RJ Ward, L Chioato, AHC de OLIVEIRA, R Ruller, JM Sá
Biochemical Journal 362 (1), 89-96, 2002
1342002
Dissociation of enzymatic and pharmacological properties of piratoxins-I and-III, two myotoxic phospholipases A2 from Bothrops pirajai snake venom
AM Soares, SH Andrião-Escarso, RK Bortoleto, L Rodrigues-Simioni, ...
Archives of Biochemistry and Biophysics 387 (2), 188-196, 2001
1252001
Crystallographic and spectroscopic characterization of a molecular hinge: Conformational changes in bothropstoxin I, a dimeric Lys49‐phospholipase A2 homologue
MT da Silva Giotto, RC Garratt, G Oliva, YP Mascarenhas, JR Giglio, ...
Proteins: Structure, Function, and Bioinformatics 30 (4), 442-454, 1998
1171998
Crystallographic and spectroscopic characterization of a molecular hinge: Conformational changes in bothropstoxin I, a dimeric Lys49‐phospholipase A2 homologue
MT da Silva Giotto, RC Garratt, G Oliva, YP Mascarenhas, JR Giglio, ...
Proteins: Structure, Function, and Bioinformatics 30 (4), 442-454, 1998
1171998
Glucose tolerant and glucose stimulated β-glucosidases–a review
JCS Salgado, LP Meleiro, S Carli, RJ Ward
Bioresource technology 267, 704-713, 2018
1142018
Mapping structural determinants of biological activities in snake venom phospholipases A2 by sequence analysis and site directed mutagenesis
L Chioato, RJ Ward
Toxicon 42 (8), 869-883, 2003
1122003
Isolation, purification, and physicochemical characterization of a D-galactose-binding lectin from seeds of Erythrina speciosa
EHE Konozy, ES Bernardes, C Rosa, V Faca, LJ Greene, RJ Ward
Archives of Biochemistry and Biophysics 410 (2), 222-229, 2003
1052003
Dissecting structure–function–stability relationships of a thermostable GH5-CBM3 cellulase from Bacillus subtilis 168
CR Santos, JH Paiva, ML Sforca, JL Neves, RZ Navarro, J Cota, PK Akao, ...
Biochemical Journal 441 (1), 95-104, 2012
1012012
Distinct sites for myotoxic and membrane-damaging activities in the C-terminal region of a Lys49-phospholipase A2
L Chioato, AHC OLIVEIRA, R Ruller, JM Sá, RJ Ward
Biochemical journal 366 (3), 971-976, 2002
922002
Thermostable variants of the recombinant xylanase a from Bacillus subtilis produced by directed evolution show reduced heat capacity changes
R Ruller, L Deliberto, TL Ferreira, RJ Ward
Proteins: Structure, Function, and Bioinformatics 70 (4), 1280-1293, 2008
912008
A molecular mechanism for Lys49-phospholipase A2 activity based on ligand-induced conformational change
ALB Ambrosio, MC Nonato, HSS de Araújo, R Arni, RJ Ward, CL Ownby, ...
Journal of Biological Chemistry 280 (8), 7326-7335, 2005
882005
Engineering the pattern of protein glycosylation modulates the thermostability of a GH11 xylanase
R Fonseca-Maldonado, DS Vieira, JS Alponti, E Bonneil, P Thibault, ...
Journal of biological chemistry 288 (35), 25522-25534, 2013
872013
Structural and functional analysis of BmjMIP, a phospholipase A2 myotoxin inhibitor protein from Bothrops moojeni snake plasma
AM Soares, S Marcussi, RG Stábeli, SC França, JR Giglio, RJ Ward, ...
Biochemical and biophysical research communications 302 (2), 193-200, 2003
872003
Histidine residues near the N terminus of staphylococcal alpha-toxin as reporters of regions that are critical for oligomerization and pore formation
R Jursch, A Hildebrand, G Hobom, J Tranum-Jensen, R Ward, M Kehoe, ...
Infection and immunity 62 (6), 2249-2256, 1994
871994
Synthetic biology approaches to improve biocatalyst identification in metagenomic library screening
ME Guazzaroni, R Silva‐Rocha, RJ Ward
Microbial Biotechnology 8 (1), 52-64, 2015
802015
Biochemical and structural characterization of a β-1, 3–1, 4-glucanase from Bacillus subtilis 168
GP Furtado, LF Ribeiro, CR Santos, CC Tonoli, AR De Souza, RR Oliveira, ...
Process Biochemistry 46 (5), 1202-1206, 2011
792011
Mapping of the structural determinants of artificial and biological membrane damaging activities of a Lys49 phospholipase A2 by scanning alanine mutagenesis
L Chioato, EA Aragão, TL Ferreira, AI de Medeiros, LH Faccioli, RJ Ward
Biochimica et Biophysica Acta (BBA)-Biomembranes 1768 (5), 1247-1257, 2007
792007
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