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Elaine Ngan
Elaine Ngan
McGill University Goodman Cancer Research Center
Dirección de correo verificada de mail.mcgill.ca
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Signaling through ShcA is required for transforming growth factor β-and Neu/ErbB-2-induced breast cancer cell motility and invasion
JJ Northey, J Chmielecki, E Ngan, C Russo, MG Annis, WJ Muller, ...
Molecular and cellular biology 28 (10), 3162-3176, 2008
992008
Genetic and pharmacologic inhibition of eIF4E reduces breast cancer cell migration, invasion, and metastasis
F Pettersson, SV Del Rincon, A Emond, B Huor, E Ngan, J Ng, ...
Cancer research 75 (6), 1102-1112, 2015
862015
LPP is a Src substrate required for invadopodia formation and efficient breast cancer lung metastasis
E Ngan, K Stoletov, HW Smith, J Common, WJ Muller, JD Lewis, ...
Nature communications 8 (1), 15059, 2017
732017
A complex containing LPP and α-actinin mediates TGFβ-induced migration and invasion of ErbB2-expressing breast cancer cells
E Ngan, JJ Northey, CM Brown, J Ursini-Siegel, PM Siegel
J Cell Sci 126 (9), 1981-1991, 2013
582013
Distinct phosphotyrosine-dependent functions of the ShcA adaptor protein are required for transforming growth factor β (TGFβ)-induced breast cancer cell migration, invasion …
JJ Northey, Z Dong, E Ngan, A Kaplan, WR Hardy, T Pawson, PM Siegel
Journal of Biological Chemistry 288 (7), 5210-5222, 2013
342013
Distinct Phosphotyrosine-dependent Functions of the ShcA Adaptor Protein Are Required for Transforming Growth Factor β (TGFβ)-induced Breast Cancer Cell Migration, Invasion …
JJ Northey, Z Dong, E Ngan, A Kaplan, WR Hardy, T Pawson, PM Siegel
Journal of Biological Chemistry 288 (7), 5210-5222, 2013
342013
Emerging roles for LPP in metastatic cancer progression
E Ngan, A Kiepas, CM Brown, PM Siegel
Journal of cell communication and signaling 12, 143-156, 2018
302018
Real-World Study to Assess Patterns of Treatment Practices and Clinical Outcomes in Metastatic Colorectal Cancer Patients with RAS Wild-Type Left-Sided …
DJ Boyne, E Ngan, C Carbonell, RJ Wani, C Cirone Morris, DJ Martinez, ...
Current Oncology 30 (9), 8220-8232, 2023
12023
Real-World Safety and Effectiveness of a bevacizumab biosimilar (ABP 215) in Metastatic Colorectal Cancer Patients in Canada
WY Cheung, S Samimi, K Ma, G Knight, S Kassam, B Colwell, A Beaudoin, ...
Clinical Colorectal Cancer, 2023
2023
Real-world safety and effectiveness of MVASI in metastatic colorectal cancer patients in Canada.
WY Cheung, S Samimi, K Ma, GJ Knight, SN Kassam, B Colwell, ...
Journal of Clinical Oncology 41 (16_suppl), e15555-e15555, 2023
2023
Real-world use of biologics and its association with outcomes in RAS wild-type (WT) left-sided metastatic colorectal cancer (mCRC) in Canada.
WY Cheung, DJ Boyne, DR Brenner, D Martinez, RJ Wani, E Ngan
Journal of Clinical Oncology 41 (4_suppl), 56-56, 2023
2023
P-28 Real-world observational study of MVASI in metastatic colorectal cancer patients in Canada: Baseline patient characteristics
W Cheung, S Samimi, S Kassam, B Colwell, P Meyer, G Knight, K Ma, ...
Annals of Oncology 33, S257, 2022
2022
LPP Promotes Breast Cancer Metastasis and is Required for Invadopodia formation
E Ngan, K Stoletov, Z Dong, J Common, JD Lewis, PM Siegel
Defining the pro-metastatic functions of LPP in breast cancer, 119, 2016
2016
Src-mediated Phosphorylation of Distinct Tyrosine Residues within LPP is Critical for Breast Cancer Invasion
E Ngan, HW Smith, WJ Muller, PM Siegel
Defining the pro-metastatic functions of LPP in breast cancer, 168, 2016
2016
Defining the pro-metastatic functions of LPP in breast cancer
E Ngan
McGill University (Canada), 2016
2016
LPP promotes ErbB2 overexpressing breast cancer cell migration, invasion and metastasis
E Ngan, PM Siegel
Cancer Research 74 (19_Supplement), 2093-2093, 2014
2014
TGF-beta induced epithelial-to-mesenchymal transition is attenuated when the MNK/eIF4E pathway is functionally impaired.
SV del Rincon, B Huor, E Ngan, L Petruccelli, P Siegel, WH Miller
Cancer Research 73 (8 Supplement), 288-288, 2013
2013
Distinct phospho-tyrosine dependent functions of ShcA are required for TGFβ-induced breast cancer cell migration, invasion and metastasis
JJ Northey, Z Dong, E Ngan, A Kaplan, WR Hardy, T Pawson, PM Siegel
Journal of Biological Chemistry, jbc. M112. 424804, 2012
2012
Breast cancer cells that undergo an Epithelial-to-Mesenchymal transition co-opt LPP, a regulator of mesenchymal cell migration and invasion.
E Ngan, JJ Northey, J Ursini-Siegel, PM Siegel
CANCER RESEARCH 72, 2012
2012
Abstract P1-05-22: Breast cancer cells that undergo an Epithelial-to-Mesenchymal transition co-opt LPP, a regulator of mesenchymal cell migration and invasion.
E Ngan, JJ Northey, J Ursini-Siegel, PM Siegel
Cancer Research 72 (24_Supplement), P1-05-22-P1-05-22, 2012
2012
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