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Fang Bai
Fang Bai
Other namesBai, Fang
Assistant Professor/Research Professor (PI)/Shanghaitech University
Verified email at shanghaitech.edu.cn - Homepage
Title
Cited by
Cited by
Year
Structure of Mpro from SARS-CoV-2 and discovery of its inhibitors
Z Jin, X Du, Y Xu, Y Deng, M Liu, Y Zhao, B Zhang, X Li, L Zhang, C Peng, ...
Nature 582 (7811), 289-293, 2020
38582020
Structure-based design of antiviral drug candidates targeting the SARS-CoV-2 main protease
W Dai, B Zhang, XM Jiang, H Su, J Li, Y Zhao, X Xie, Z Jin, J Peng, F Liu, ...
Science 368 (6497), 1331-1335, 2020
13452020
Structural basis for molecular recognition at serotonin receptors
C Wang, Y Jiang, J Ma, H Wu, D Wacker, V Katritch, GW Han, W Liu, ...
Science 340 (6132), 610-614, 2013
5972013
Anti-SARS-CoV-2 activities in vitro of Shuanghuanglian preparations and bioactive ingredients
H Su, S Yao, W Zhao, M Li, J Liu, W Shang, H Xie, C Ke, H Hu, M Gao, ...
Acta Pharmacologica Sinica 41 (9), 1167-1177, 2020
3502020
Targeting CPT1A-mediated fatty acid oxidation sensitizes nasopharyngeal carcinoma to radiation therapy
Z Tan, L Xiao, M Tang, F Bai, J Li, L Li, F Shi, N Li, Y Li, Q Du, J Lu, ...
Theranostics 8 (9), 2329, 2018
1652018
Discovery of baicalin and baicalein as novel, natural product inhibitors of SARS-CoV-2 3CL protease in vitro
H Su, S Yao, W Zhao, M Li, J Liu, WJ Shang, H Xie, C Ke, M Gao, K Yu, ...
BioRxiv, 2020.04. 13.038687, 2020
1442020
NEET proteins: a new link between iron metabolism, reactive oxygen species, and cancer
R Mittler, M Darash-Yahana, YS Sohn, F Bai, L Song, IZ Cabantchik, ...
Antioxidants & redox signaling 30 (8), 1083-1095, 2019
1412019
Enhancing intracellular accumulation and target engagement of PROTACs with reversible covalent chemistry
WH Guo, X Qi, X Yu, Y Liu, CI Chung, F Bai, X Lin, D Lu, L Wang, J Chen, ...
Nature communications 11 (1), 4268, 2020
1272020
Free energy landscape for the binding process of Huperzine A to acetylcholinesterase
F Bai, Y Xu, J Chen, Q Liu, J Gu, X Wang, J Ma, H Li, JN Onuchic, H Jiang
Proceedings of the National Academy of Sciences 110 (11), 4273-4278, 2013
952013
Redox-dependent gating of VDAC by mitoNEET
CH Lipper, JT Stofleth, F Bai, YS Sohn, S Roy, R Mittler, R Nechushtai, ...
Proceedings of the National Academy of Sciences 116 (40), 19924-19929, 2019
922019
The Fe-S cluster-containing NEET proteins mitoNEET and NAF-1 as chemotherapeutic targets in breast cancer
F Bai, F Morcos, YS Sohn, M Darash-Yahana, CO Rezende, CH Lipper, ...
Proceedings of the National Academy of Sciences 112 (12), 3698-3703, 2015
842015
Elucidating the druggable interface of protein− protein interactions using fragment docking and coevolutionary analysis
F Bai, F Morcos, RR Cheng, H Jiang, JN Onuchic
Proceedings of the National Academy of Sciences 113 (50), E8051-E8058, 2016
782016
Breast cancer tumorigenicity is dependent on high expression levels of NAF-1 and the lability of its Fe-S clusters
M Darash-Yahana, Y Pozniak, M Lu, YS Sohn, O Karmi, S Tamir, F Bai, ...
Proceedings of the National Academy of Sciences 113 (39), 10890-10895, 2016
732016
Structure-based drug design, virtual screening and high-throughput screening rapidly identify antiviral leads targeting COVID-19
Z Jin, X Du, Y Xu, Y Deng, M Liu, Y Zhao, B Zhang, X Li, L Zhang, C Peng, ...
702020
Identification of matrine as a promising novel drug for hepatic steatosis and glucose intolerance with HSP 72 as an upstream target
XY Zeng, H Wang, F Bai, X Zhou, SP Li, LP Ren, RQ Sun, CCL Xue, ...
British journal of pharmacology 172 (17), 4303-4318, 2015
662015
Cyndi: a multi-objective evolution algorithm based method for bioactive molecular conformational generation
X Liu, F Bai, S Ouyang, X Wang, H Li, H Jiang
BMC bioinformatics 10, 1-14, 2009
622009
Discovery of Pteridin-7(8H)-one-Based Irreversible Inhibitors Targeting the Epidermal Growth Factor Receptor (EGFR) Kinase T790M/L858R Mutant
W Zhou, X Liu, Z Tu, L Zhang, X Ku, F Bai, Z Zhao, Y Xu, K Ding, H Li
Journal of medicinal chemistry 56 (20), 7821-7837, 2013
602013
Gambogic acid identifies an isoform-specific druggable pocket in the middle domain of Hsp90β
KH Yim, TL Prince, S Qu, F Bai, PA Jennings, JN Onuchic, ...
Proceedings of the National Academy of Sciences 113 (33), E4801-E4809, 2016
572016
A multi-targeting drug design strategy for identifying potent anti-SARS-CoV-2 inhibitors
P Ren, W Shang, W Yin, H Ge, L Wang, X Zhang, B Li, H Li, Y Xu, EH Xu, ...
Acta Pharmacologica Sinica 43 (2), 483-493, 2022
482022
Interactions between mitoNEET and NAF-1 in cells
O Karmi, SH Holt, L Song, S Tamir, Y Luo, F Bai, A Adenwalla, ...
PloS one 12 (4), e0175796, 2017
442017
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