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Gregory E. Crawford
Gregory E. Crawford
Associate Professor, Duke University
Dirección de correo verificada de duke.edu
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Distinct and predictive chromatin signatures of transcriptional promoters and enhancers in the human genome
ND Heintzman, RK Stuart, G Hon, Y Fu, CW Ching, RD Hawkins, ...
Nature genetics 39 (3), 311, 2007
39142007
The accessible chromatin landscape of the human genome
RE Thurman, E Rynes, R Humbert, J Vierstra, MT Maurano, E Haugen, ...
Nature 489 (7414), 75, 2012
30552012
Histone modifications at human enhancers reflect global cell-type-specific gene expression
ND Heintzman, GC Hon, RD Hawkins, P Kheradpour, A Stark, LF Harp, ...
Nature 459 (7243), 108, 2009
28592009
Genome-wide association analyses identify 44 risk variants and refine the genetic architecture of major depression
NR Wray, S Ripke, M Mattheisen, M Trzaskowski, EM Byrne, A Abdellaoui, ...
Nature genetics 50 (5), 668, 2018
25262018
Epigenome editing by a CRISPR-Cas9-based acetyltransferase activates genes from promoters and enhancers
IB Hilton, AM D'ippolito, CM Vockley, PI Thakore, GE Crawford, TE Reddy, ...
Nature biotechnology 33 (5), 510, 2015
20482015
High-resolution mapping and characterization of open chromatin across the genome
AP Boyle, S Davis, HP Shulha, P Meltzer, EH Margulies, Z Weng, ...
Cell 132 (2), 311-322, 2008
17062008
RNA-guided gene activation by CRISPR-Cas9–based transcription factors
P Perez-Pinera, DD Kocak, CM Vockley, AF Adler, AM Kabadi, ...
Nature methods 10 (10), 973, 2013
16212013
Highly specific epigenome editing by CRISPR-Cas9 repressors for silencing of distal regulatory elements
PI Thakore, AM D'ippolito, L Song, A Safi, NK Shivakumar, AM Kabadi, ...
Nature methods 12 (12), 1143, 2015
9822015
Defining functional DNA elements in the human genome
M Kellis, B Wold, MP Snyder, BE Bernstein, A Kundaje, GK Marinov, ...
Proceedings of the National Academy of Sciences 111 (17), 6131-6138, 2014
8642014
DNase-seq: a high-resolution technique for mapping active gene regulatory elements across the genome from mammalian cells
L Song, GE Crawford
Cold Spring Harbor Protocols 2010 (2), pdb. prot5384, 2010
8102010
Comprehensive functional genomic resource and integrative model for the human brain
D Wang, S Liu, J Warrell, H Won, X Shi, FCP Navarro, D Clarke, M Gu, ...
Science 362 (6420), eaat8464, 2018
8052018
DNase I sensitivity QTLs are a major determinant of human expression variation
JF Degner, AA Pai, R Pique-Regi, JB Veyrieras, DJ Gaffney, JK Pickrell, ...
Nature 482 (7385), 390, 2012
7932012
Dynamic DNA methylation across diverse human cell lines and tissues
KE Varley, J Gertz, KM Bowling, SL Parker, TE Reddy, F Pauli-Behn, ...
Genome research, 2013
7902013
Open chromatin defined by DNaseI and FAIRE identifies regulatory elements that shape cell-type identity
L Song, Z Zhang, LL Grasfeder, AP Boyle, PG Giresi, BK Lee, ...
Genome research, 2011
6232011
Genome-wide mapping of DNase hypersensitive sites using massively parallel signature sequencing (MPSS)
GE Crawford, IE Holt, J Whittle, BD Webb, D Tai, S Davis, EH Margulies, ...
Genome research 16 (1), 123-131, 2006
6062006
Retroviral DNA integration: viral and cellular determinants of target-site selection
MK Lewinski, M Yamashita, M Emerman, A Ciuffi, H Marshall, G Crawford, ...
PLoS pathogens 2 (6), e60, 2006
4772006
CRISPR–Cas9 epigenome editing enables high-throughput screening for functional regulatory elements in the human genome
TS Klann, JB Black, M Chellappan, A Safi, L Song, IB Hilton, GE Crawford, ...
Nature biotechnology 35 (6), 561, 2017
4512017
F-Seq: a feature density estimator for high-throughput sequence tags
AP Boyle, J Guinney, GE Crawford, TS Furey
Bioinformatics 24 (21), 2537-2538, 2008
4382008
Transcriptome-wide association study of schizophrenia and chromatin activity yields mechanistic disease insights
A Gusev, N Mancuso, H Won, M Kousi, HK Finucane, Y Reshef, L Song, ...
Nature genetics 50 (4), 538, 2018
4272018
High-resolution genome-wide in vivo footprinting of diverse transcription factors in human cells
AP Boyle, L Song, BK Lee, D London, D Keefe, E Birney, VR Iyer, ...
Genome research, gr. 112656.110, 2010
4112010
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Artículos 1–20