Abnormal liver function tests in patients with COVID‐19: relevance and potential pathogenesis A Bertolini, IP van De Peppel, FAJA Bodewes, H Moshage, A Fantin, ... Hepatology 72 (5), 1864-1872, 2020 | 308 | 2020 |
The role of lipophagy in the development and treatment of non-alcoholic fatty liver disease A Grefhorst, IP van de Peppel, LE Larsen, JW Jonker, AG Holleboom Frontiers in endocrinology 11, 601627, 2021 | 71 | 2021 |
Pegbelfermin (BMS-986036): an investigational PEGylated fibroblast growth factor 21 analogue for the treatment of nonalcoholic steatohepatitis CRC Verzijl, IP Van De Peppel, D Struik, JW Jonker Expert opinion on investigational drugs 29 (2), 125-133, 2020 | 53 | 2020 |
IVACAFTOR restores FGF19 regulated bile acid homeostasis in cystic fibrosis patients with an S1251N or a G551D gating mutation IP van de Peppel, M Doktorova, G Berkers, HR de Jonge, RHJ Houwen, ... Journal of Cystic Fibrosis 18 (2), 286-293, 2019 | 33 | 2019 |
Efficient reabsorption of transintestinally excreted cholesterol is a strong determinant for cholesterol disposal in mice [S] IP van de Peppel, A Bertolini, TH van Dijk, AK Groen, JW Jonker, ... Journal of Lipid Research 60 (9), 1562-1572, 2019 | 29 | 2019 |
Metabolic consequences of ileal interruption of the enterohepatic circulation of bile acids IP van de Peppel, HJ Verkade, JW Jonker American Journal of Physiology-Gastrointestinal and Liver Physiology 319 (5 …, 2020 | 28 | 2020 |
Diagnosis, follow-up and treatment of cystic fibrosis-related liver disease IP van de Peppel, A Bertolini, JW Jonker, FAJA Bodewes, HJ Verkade Current Opinion in Pulmonary Medicine 23 (6), 562-569, 2017 | 26 | 2017 |
Translational model of melphalan-induced gut toxicity reveals drug-host-microbe interactions that drive tissue injury and fever HR Wardill, CEM de Mooij, AR da Silva Ferreira, IP van de Peppel, ... Cancer Chemotherapy and Pharmacology 88, 173-188, 2021 | 21 | 2021 |
Bile acid homeostasis in gastrointestinal and metabolic complications of cystic fibrosis IP van de Peppel, FAJA Bodewes, HJ Verkade, JW Jonker Journal of Cystic Fibrosis 18 (3), 313-320, 2019 | 21 | 2019 |
Attenuation of the hepatoprotective effects of ileal apical sodium dependent bile acid transporter (ASBT) inhibition in choline-deficient L-amino acid-defined (CDAA) diet-fed mice A Rao, IP Peppel, S Gumber, SJ Karpen, PA Dawson Frontiers in Medicine 7, 60, 2020 | 17 | 2020 |
Defective FXR-FGF15 signaling and bile acid homeostasis in cystic fibrosis mice can be restored by the laxative polyethylene glycol A Bertolini, IP van de Peppel, M Doktorova-Demmin, FAJA Bodewes, ... American Journal of Physiology-Gastrointestinal and Liver Physiology 316 (3 …, 2019 | 15 | 2019 |
The Beneficial Effects of Apical Sodium‐Dependent Bile Acid Transporter Inactivation Depend on Dietary Fat Composition IP van de Peppel, A Rao, MB Dommerholt, L Bongiovanni, R Thomas, ... Molecular Nutrition & Food Research 64 (24), 2000750, 2020 | 14 | 2020 |
Inactivation of the Intestinal Apical Sodium Bile Acid Transporter Profoundly Inhibits Cholesterol Absorption. IP Van De Peppel, A Bertolini, TH Van Dijk, ABK Groen, JW Jonker, ... Hepatology 68, 823A-824A, 2018 | 3 | 2018 |
Ivacaftor restores the enterohepatic feedback regulation of the bile acid homeostasis in patients with a Cftr G551D mutation F Bodewes, M Doktorova, I van de Peppel, C Ley, J Jonker, H Verkade Pediatric Pulmonology 50, 297-297, 2015 | 3 | 2015 |
Pharmacological inhibition of MEK1/2 signaling disrupts bile acid metabolism through loss of Shp and enhanced Cyp7a1 expression CRC Verzijl, IP van de Peppel, RE Eilers, VW Bloks, JC Wolters, ... Biomedicine & Pharmacotherapy 159, 114270, 2023 | 1 | 2023 |
Induction of fecal cholesterol excretion is not effective for the treatment of hyperbilirubinemia in Gunn rats M Blankestijn, IP van de Peppel, A Dvorak, N Capkova, L Vitek, ... Pediatric Research 89 (3), 510-517, 2021 | 1 | 2021 |
Intestinal bile acid reabsorption in health and disease IP van de Peppel | 1 | 2019 |
Treatment of intestinal and liver features in cystic fibrosis mice by the osmotic laxative polyethylene glycol A Bertolini, VW Bloks, M Wilmink, E Bos, IP van de Peppel, R Eilers, ... Journal of Cystic Fibrosis, 2023 | | 2023 |
Commentary: The mutations and clinical variability in maternally inherited diabetes and deafness: an analysis of 161 patients IP van de Peppel, S Demirdas, B Özcan Frontiers in Endocrinology 14, 1205862, 2023 | | 2023 |
The Apical Sodium-Dependent Bile Acid Transporter in Cholangiocytes Is Not Required for the Generation of Bile Flow in Mice A Bertolini, IP van de Peppel, R Havinga, JW Jonker, HJ Verkade Gastro Hep Advances 1 (3), 375-377, 2022 | | 2022 |