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Ivo Pieter van de Peppel
Ivo Pieter van de Peppel
Post-doc Laboratory of Pediatrics, University Medical Center Groningen
Dirección de correo verificada de umcg.nl
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Abnormal liver function tests in patients with COVID‐19: relevance and potential pathogenesis
A Bertolini, IP van De Peppel, FAJA Bodewes, H Moshage, A Fantin, ...
Hepatology 72 (5), 1864-1872, 2020
3082020
The role of lipophagy in the development and treatment of non-alcoholic fatty liver disease
A Grefhorst, IP van de Peppel, LE Larsen, JW Jonker, AG Holleboom
Frontiers in endocrinology 11, 601627, 2021
712021
Pegbelfermin (BMS-986036): an investigational PEGylated fibroblast growth factor 21 analogue for the treatment of nonalcoholic steatohepatitis
CRC Verzijl, IP Van De Peppel, D Struik, JW Jonker
Expert opinion on investigational drugs 29 (2), 125-133, 2020
532020
IVACAFTOR restores FGF19 regulated bile acid homeostasis in cystic fibrosis patients with an S1251N or a G551D gating mutation
IP van de Peppel, M Doktorova, G Berkers, HR de Jonge, RHJ Houwen, ...
Journal of Cystic Fibrosis 18 (2), 286-293, 2019
332019
Efficient reabsorption of transintestinally excreted cholesterol is a strong determinant for cholesterol disposal in mice [S]
IP van de Peppel, A Bertolini, TH van Dijk, AK Groen, JW Jonker, ...
Journal of Lipid Research 60 (9), 1562-1572, 2019
292019
Metabolic consequences of ileal interruption of the enterohepatic circulation of bile acids
IP van de Peppel, HJ Verkade, JW Jonker
American Journal of Physiology-Gastrointestinal and Liver Physiology 319 (5 …, 2020
282020
Diagnosis, follow-up and treatment of cystic fibrosis-related liver disease
IP van de Peppel, A Bertolini, JW Jonker, FAJA Bodewes, HJ Verkade
Current Opinion in Pulmonary Medicine 23 (6), 562-569, 2017
262017
Translational model of melphalan-induced gut toxicity reveals drug-host-microbe interactions that drive tissue injury and fever
HR Wardill, CEM de Mooij, AR da Silva Ferreira, IP van de Peppel, ...
Cancer Chemotherapy and Pharmacology 88, 173-188, 2021
212021
Bile acid homeostasis in gastrointestinal and metabolic complications of cystic fibrosis
IP van de Peppel, FAJA Bodewes, HJ Verkade, JW Jonker
Journal of Cystic Fibrosis 18 (3), 313-320, 2019
212019
Attenuation of the hepatoprotective effects of ileal apical sodium dependent bile acid transporter (ASBT) inhibition in choline-deficient L-amino acid-defined (CDAA) diet-fed mice
A Rao, IP Peppel, S Gumber, SJ Karpen, PA Dawson
Frontiers in Medicine 7, 60, 2020
172020
Defective FXR-FGF15 signaling and bile acid homeostasis in cystic fibrosis mice can be restored by the laxative polyethylene glycol
A Bertolini, IP van de Peppel, M Doktorova-Demmin, FAJA Bodewes, ...
American Journal of Physiology-Gastrointestinal and Liver Physiology 316 (3 …, 2019
152019
The Beneficial Effects of Apical Sodium‐Dependent Bile Acid Transporter Inactivation Depend on Dietary Fat Composition
IP van de Peppel, A Rao, MB Dommerholt, L Bongiovanni, R Thomas, ...
Molecular Nutrition & Food Research 64 (24), 2000750, 2020
142020
Inactivation of the Intestinal Apical Sodium Bile Acid Transporter Profoundly Inhibits Cholesterol Absorption.
IP Van De Peppel, A Bertolini, TH Van Dijk, ABK Groen, JW Jonker, ...
Hepatology 68, 823A-824A, 2018
32018
Ivacaftor restores the enterohepatic feedback regulation of the bile acid homeostasis in patients with a Cftr G551D mutation
F Bodewes, M Doktorova, I van de Peppel, C Ley, J Jonker, H Verkade
Pediatric Pulmonology 50, 297-297, 2015
32015
Pharmacological inhibition of MEK1/2 signaling disrupts bile acid metabolism through loss of Shp and enhanced Cyp7a1 expression
CRC Verzijl, IP van de Peppel, RE Eilers, VW Bloks, JC Wolters, ...
Biomedicine & Pharmacotherapy 159, 114270, 2023
12023
Induction of fecal cholesterol excretion is not effective for the treatment of hyperbilirubinemia in Gunn rats
M Blankestijn, IP van de Peppel, A Dvorak, N Capkova, L Vitek, ...
Pediatric Research 89 (3), 510-517, 2021
12021
Intestinal bile acid reabsorption in health and disease
IP van de Peppel
12019
Treatment of intestinal and liver features in cystic fibrosis mice by the osmotic laxative polyethylene glycol
A Bertolini, VW Bloks, M Wilmink, E Bos, IP van de Peppel, R Eilers, ...
Journal of Cystic Fibrosis, 2023
2023
Commentary: The mutations and clinical variability in maternally inherited diabetes and deafness: an analysis of 161 patients
IP van de Peppel, S Demirdas, B Özcan
Frontiers in Endocrinology 14, 1205862, 2023
2023
The Apical Sodium-Dependent Bile Acid Transporter in Cholangiocytes Is Not Required for the Generation of Bile Flow in Mice
A Bertolini, IP van de Peppel, R Havinga, JW Jonker, HJ Verkade
Gastro Hep Advances 1 (3), 375-377, 2022
2022
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