Cellular senescence mediates fibrotic pulmonary disease MJ Schafer, TA White, K Iijima, AJ Haak, G Ligresti, EJ Atkinson, AL Oberg, ... Nature communications 8 (1), 14532, 2017 | 1352 | 2017 |
PIK3CA mutations in human solid tumors: role in sensitivity to various therapeutic approaches G Ligresti, L Militello, LS Steelman, A Cavallaro, F Basile, F Nicoletti, ... Cell cycle 8 (9), 1352-1358, 2009 | 255 | 2009 |
Mechanosensing and fibrosis DJ Tschumperlin, G Ligresti, MB Hilscher, VH Shah The Journal of clinical investigation 128 (1), 74-84, 2018 | 252 | 2018 |
Targeting the leukemic stem cell: the Holy Grail of leukemia therapy N Misaghian, G Ligresti, LS Steelman, FE Bertrand, J Bäsecke, M Libra, ... Leukemia 23 (1), 25-42, 2009 | 251 | 2009 |
Cellular mechanisms of tissue fibrosis. 3. Novel mechanisms of kidney fibrosis G Campanholle, G Ligresti, SA Gharib, JS Duffield American Journal of Physiology-Cell Physiology 304 (7), C591-C603, 2013 | 241 | 2013 |
Extracellular matrix: a matter of life and death S Marastoni, G Ligresti, E Lorenzon, A Colombatti, M Mongiat Connective tissue research 49 (3-4), 203-206, 2008 | 221 | 2008 |
Gene alterations in the PI3K/PTEN/AKT pathway as a mechanism of drug-resistance S Hafsi, FM Pezzino, S Candido, G Ligresti, DA Spandidos, Z Soua, ... International journal of oncology 40 (3), 639-644, 2012 | 193 | 2012 |
Selective YAP/TAZ inhibition in fibroblasts via dopamine receptor D1 agonism reverses fibrosis AJ Haak, E Kostallari, D Sicard, G Ligresti, KM Choi, N Caporarello, ... Science translational medicine 11 (516), eaau6296, 2019 | 184 | 2019 |
The involvement of the transcription factor Yin Yang 1 in cancer development and progression G Castellano, E Torrisi, G Ligresti, G Malaponte, L Militello, AE Russo, ... Cell cycle 8 (9), 1367-1372, 2009 | 174 | 2009 |
A novel three–dimensional human peritubular microvascular system G Ligresti, RJ Nagao, J Xue, YJ Choi, J Xu, S Ren, T Aburatani, ... Journal of the American Society of Nephrology 27 (8), 2370-2381, 2016 | 106 | 2016 |
MULTIMERIN2 impairs tumor angiogenesis and growth by interfering with VEGF-A/VEGFR2 pathway E Lorenzon, R Colladel, E Andreuzzi, S Marastoni, F Todaro, ... Oncogene 31 (26), 3136-3147, 2012 | 102 | 2012 |
Regulation of the extrinsic apoptotic pathway by the extracellular matrix glycoprotein EMILIN2 M Mongiat, G Ligresti, S Marastoni, E Lorenzon, R Doliana, A Colombatti Molecular and cellular biology 27 (20), 7176-7187, 2007 | 100 | 2007 |
COVID-19 vasculopathy: mounting evidence for an indirect mechanism of endothelial injury RF Nicosia, G Ligresti, N Caporarello, S Akilesh, D Ribatti The American journal of pathology 191 (8), 1374-1384, 2021 | 99 | 2021 |
Involvement of p53 and Raf/MEK/ERK pathways in hematopoietic drug resistance JA McCubrey, SL Abrams, G Ligresti, N Misaghian, EWT Wong, ... Leukemia 22 (11), 2080-2090, 2008 | 95 | 2008 |
PGC1α repression in IPF fibroblasts drives a pathologic metabolic, secretory and fibrogenic state N Caporarello, JA Meridew, DL Jones, Q Tan, AJ Haak, KM Choi, ... Thorax 74 (8), 749-760, 2019 | 87 | 2019 |
CBX5/G9a/H3K9me-mediated gene repression is essential to fibroblast activation during lung fibrosis G Ligresti, N Caporarello, JA Meridew, DL Jones, Q Tan, KM Choi, ... JCI insight 4 (12), 2019 | 72 | 2019 |
The acute phase reactant orosomucoid-1 is a bimodal regulator of angiogenesis with time-and context-dependent inhibitory and stimulatory properties G Ligresti, AC Aplin, BE Dunn, A Morishita, RF Nicosia Public Library of Science 7 (8), e41387, 2012 | 70 | 2012 |
Yin Yang 1 overexpression in diffuse large B-cell lymphoma is associated with B-cell transformation and tumor progression G Castellano, E Torrisi, G Ligresti, F Nicoletti, G Malaponte, S Travali, ... Cell cycle 9 (3), 557-563, 2010 | 65 | 2010 |
Dicer1 activity in the stromal compartment regulates nephron differentiation and vascular patterning during mammalian kidney organogenesis N Nakagawa, C Xin, AM Roach, N Naiman, SJ Shankland, G Ligresti, ... Kidney international 87 (6), 1125-1140, 2015 | 63 | 2015 |
TGFβ-induced fibroblast activation requires persistent and targeted HDAC-mediated gene repression DL Jones, AJ Haak, N Caporarello, KM Choi, Z Ye, H Yan, X Varelas, ... Journal of cell science 132 (20), jcs233486, 2019 | 62 | 2019 |