Jesus Angulo
Jesus Angulo
CSIC-Research Scientist (Investigador Científico-CSIC). Group Leader
Verified email at - Homepage
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Ligand–Receptor Binding Affinities from Saturation Transfer Difference (STD) NMR Spectroscopy: The Binding Isotherm of STD Initial Growth Rates
J Angulo, PM Enríquez‐Navas, PM Nieto
Chemistry-A European Journal 16 (26), 7803-7812, 2010
STD-NMR: application to transient interactions between biomolecules—a quantitative approach
J Angulo, PM Nieto
European biophysics journal 40 (12), 1357-1369, 2011
The activation of fibroblast growth factors by heparin: Synthesis, structure, and biological activity of heparin‐like oligosaccharides
JL de Paz, J Angulo, JM Lassaletta, PM Nieto, M Redondo‐Horcajo, ...
ChemBioChem 2 (9), 673-685, 2001
Elucidation of a sialic acid metabolism pathway in mucus-foraging Ruminococcus gnavus unravels mechanisms of bacterial adaptation to the gut
A Bell, J Brunt, E Crost, L Vaux, R Nepravishta, CD Owen, D Latousakis, ...
Nature microbiology 4 (12), 2393-2404, 2019
Conformational flexibility of a synthetic glycosylaminoglycan bound to a fibroblast growth factor. FGF-1 recognizes both the 1 C 4 and 2 So conformations of a bioactive heparin …
A Canales, J Angulo, R Ojeda, M Bruix, R Fayos, R Lozano, ...
Journal of the American Chemical Society 127 (16), 5778-5779, 2005
Structure of a glycomimetic ligand in the carbohydrate recognition domain of C-type lectin DC-SIGN. Structural requirements for selectivity and ligand design
M Thépaut, C Guzzi, I Sutkeviciute, S Sattin, R Ribeiro-Viana, N Varga, ...
Journal of the American Chemical Society 135 (7), 2518-2529, 2013
Blood group B galactosyltransferase: Insights into substrate binding from NMR experiments
J Angulo, B Langpap, A Blume, T Biet, B Meyer, NR Krishna, H Peters, ...
Journal of the American Chemical Society 128 (41), 13529-13538, 2006
Gold nanoparticles coated with oligomannosides of HIV-1 glycoprotein gp120 mimic the carbohydrate epitope of antibody 2G12
M Marradi, P Di Gianvincenzo, PM Enríquez-Navas, OM Martínez-Ávila, ...
Journal of molecular biology 410 (5), 798-810, 2011
Differential epitope mapping by STD NMR spectroscopy to reveal the nature of protein–ligand contacts
S Monaco, LE Tailford, N Juge, J Angulo
Angewandte Chemie International Edition 56 (48), 15289-15293, 2017
The Activation of Fibroblast Growth Factors (FGFs) by Glycosaminoglycans: Influence of the Sulfation Pattern on the Biological Activity of FGF‐1
J Angulo, R Ojeda, JL de Paz, R Lucas, PM Nieto, RM Lozano, ...
ChemBioChem 5 (1), 55-61, 2004
Saturation Transfer Difference (STD) NMR Spectroscopy Characterization of Dual Binding Mode of a Mannose Disaccharide to DC‐SIGN
J Angulo, I Díaz, JJ Reina, G Tabarani, F Fieschi, J Rojo, PM Nieto
ChemBioChem 9 (14), 2225-2227, 2008
Solution NMR structure of a human FGF‐1 monomer, activated by a hexasaccharide heparin‐analogue
A Canales, R Lozano, B López‐Méndez, J Angulo, R Ojeda, PM Nieto, ...
FEBS Journal 273 (20), 4716-4727, 2006
Unravelling the specificity and mechanism of sialic acid recognition by the gut symbiont Ruminococcus gnavus
CD Owen, LE Tailford, S Monaco, T Šuligoj, L Vaux, R Lallement, ...
Nature communications 8 (1), 2196, 2017
Langerin–heparin interaction: Two binding sites for small and large ligands as revealed by a combination of nmr spectroscopy and cross-linking mapping experiments
JC Muñoz-García, E Chabrol, RR Vives, A Thomas, JL de Paz, J Rojo, ...
Journal of the American Chemical Society 137 (12), 4100-4110, 2015
Selective targeting of dendritic cell‐specific intercellular adhesion molecule‐3‐grabbing nonintegrin (DC‐SIGN) with mannose‐based glycomimetics: synthesis and interaction …
N Varga, I Sutkeviciute, C Guzzi, J McGeagh, I Petit‐Haertlein, S Gugliotta, ...
Chemistry–A European Journal 19 (15), 4786-4797, 2013
sp2‐Iminosugar O‐, S‐, and N‐Glycosides as Conformational Mimics of α‐Linked Disaccharides; Implications for Glycosidase Inhibition
EM Sánchez‐Fernández, R Rísquez‐Cuadro, C Ortiz Mellet, ...
Chemistry–A European Journal 18 (27), 8527-8539, 2012
Supramolecular amino acid based hydrogels: probing the contribution of additive molecules using NMR spectroscopy
SM Ramalhete, KP Nartowski, N Sarathchandra, JS Foster, AN Round, ...
Chemistry–A European Journal 23 (33), 8014-8024, 2017
Cytotoxicity of Pyrazine-Based Cyclometalated (C^Npz^C)Au(III) Carbene Complexes: Impact of the Nature of the Ancillary Ligand on the Biological Properties
B Bertrand, J Fernandez-Cestau, J Angulo, MMD Cominetti, ZAE Waller, ...
Inorganic Chemistry 56 (10), 5728-5740, 2017
Structural basis for arginine glycosylation of host substrates by bacterial effector proteins
JB Park, YH Kim, Y Yoo, J Kim, SH Jun, JW Cho, S El Qaidi, S Walpole, ...
Nature communications 9 (1), 4283, 2018
A Solution NMR Study of the Interactions of Oligomannosides and the Anti‐HIV‐1 2G12 Antibody Reveals Distinct Binding Modes for Branched Ligands
PM Enríquez‐Navas, M Marradi, D Padro, J Angulo, S Penadés
Chemistry–A European Journal 17 (5), 1547-1560, 2011
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