| Organoid cultures recapitulate esophageal adenocarcinoma heterogeneity providing a model for clonality studies and precision therapeutics X Li, HE Francies, M Secrier, J Perner, A Miremadi, N Galeano-Dalmau, ... Nature communications 9 (1), 2983, 2018 | 279 | 2018 |
| The landscape of selection in 551 esophageal adenocarcinomas defines genomic biomarkers for the clinic AM Frankell, S Jammula, X Li, G Contino, S Killcoyne, S Abbas, J Perner, ... Nature genetics 51 (3), 506-516, 2019 | 189 | 2019 |
| Prediction of human population responses to toxic compounds by a collaborative competition F Eduati, LM Mangravite, T Wang, H Tang, JC Bare, R Huang, T Norman, ... Nature biotechnology 33 (9), 933, 2015 | 119 | 2015 |
| Dynamics of Transcription Regulation in Human Bone Marrow Myeloid Differentiation to Mature Blood Neutrophils L Grassi, F Pourfarzad, S Ullrich, A Merkel, F Were, ... Cell reports 24 (10), 2784-2794, 2018 | 112 | 2018 |
| Identification of Prognostic Phenotypes of Esophageal Adenocarcinoma in 2 Independent Cohorts T Sawas, S Killcoyne, PG Iyer, KK Wang, TC Smyrk, JB Kisiel, Y Qin, ... Gastroenterology 155 (6), 1720-1728. e4, 2018 | 82 | 2018 |
| Identification of subtypes of Barrett’s Esophagus and esophageal adenocarcinoma based on DNA methylation profiles and integration of transcriptome and Genome Data SG Jammula, AC Katz-Summercorn, X Li, C Linossi, E Smyth, S Killcoyne, ... Gastroenterology 158 (6), 1682-1697. e1, 2020 | 79 | 2020 |
| Epigenomic co-localization and co-evolution reveal a key role for 5hmC as a communication hub in the chromatin network of ESCs D Juan, J Perner, EC de Santa Pau, S Marsili, D Ochoa, HR Chung, ... Cell reports 14 (5), 1246-1257, 2016 | 56 | 2016 |
| Selection and Application of Tissue microRNAs for Nonendoscopic Diagnosis of Barrett’s Esophagus X Li, S Kleeman, SB Coburn, C Fumagalli, J Perner, S Jammula, ... Gastroenterology 155 (3), 771-783. e3, 2018 | 41 | 2018 |
| Patient-specific cancer genes contribute to recurrently perturbed pathways and establish therapeutic vulnerabilities in esophageal adenocarcinoma TP Mourikis, L Benedetti, E Foxall, D Temelkovski, J Nulsen, J Perner, ... Nature Communications 10 (1), 3101, 2019 | 39 | 2019 |
| Inference of interactions between chromatin modifiers and histone modifications: from ChIP-Seq data to chromatin-signaling J Perner, J Lasserre, S Kinkley, M Vingron, HR Chung Nucleic acids research 42 (22), 13689-13695, 2014 | 32 | 2014 |
| Impact of mutations in Toll-like receptor pathway genes on esophageal carcinogenesis DR Fels Elliott, J Perner, X Li, MF Symmons, B Verstak, M Eldridge, ... PLoS genetics 13 (5), e1006808, 2017 | 31 | 2017 |
| Transcriptomic profiling reveals three molecular phenotypes of adenocarcinoma at the gastroesophageal junction J Bornschein, L Wernisch, M Secrier, A Miremadi, J Perner, S MacRae, ... International journal of cancer 145 (12), 3389-3401, 2019 | 26 | 2019 |
| Immune activation by DNA damage predicts response to chemotherapy and survival in oesophageal adenocarcinoma RC Turkington, LA Knight, JK Blayney, M Secrier, R Douglas, EE Parkes, ... Gut 68 (11), 1918-1927, 2019 | 25 | 2019 |
| Epigenetic regulation of Amphiregulin and Epiregulin in colorectal cancer F Bormann, S Stinzing, S Tierling, M Morkel, MR Markelova, J Walter, ... International journal of cancer 144 (3), 569-581, 2019 | 20 | 2019 |
| Oesophageal Cancer Clinical and Molecular Stratification (OCCAMS) Consortium The landscape of selection in 551 esophageal adenocarcinomas defines genomic biomarkers for the clinic AM Frankell, S Jammula, X Li, G Contino, S Killcoyne, S Abbas, J Perner, ... Nature Genetics 51, 506-516, 2019 | 16* | 2019 |
| The mutREAD method detects mutational signatures from low quantities of cancer DNA J Perner, S Abbas, K Nowicki-Osuch, G Devonshire, MD Eldridge, ... Nature Communications 11 (1), 3166, 2020 | 11 | 2020 |
| Drug-induced chromatin accessibility changes associate with sensitivity to liver tumor promotion A Vitobello, J Perner, J Beil, J Zhu, A Del Río-Espínola, L Morawiec, ... Life science alliance 2 (5), 2019 | 8 | 2019 |
| Identification of marker genes to monitor residual iPSCs in iPSC-derived products M Lemmens, J Perner, L Potgeter, M Zogg, S Thiruchelvam, M Müller, ... Cytotherapy 25 (1), 59-67, 2023 | 7 | 2023 |
| Chromatin signaling and transcription initiation J Perner, HR Chung Frontiers in Life Science 7 (1-2), 22-30, 2013 | 7 | 2013 |
| Characterizing cell types through differentially expressed gene clusters using a model-based approach J Perner, E Zotenko Industrial Conference on Data Mining, 106-120, 2011 | 6 | 2011 |
Rebecca FitzgeraldProfessor of Cancer Prevention, Cambridge UniversityDirección de correo verificada de cam.ac.uk
