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Ganesh Thakur
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Cannabinergic ligands
SL Palmer, GA Thakur, A Makriyannis
Chemistry and Physics of Lipids 121 (1-2), 3-19, 2002
1982002
The novel cannabinoid CB1 receptor neutral antagonist AM4113 suppresses food intake and food-reinforced behavior but does not induce signs of nausea in rats
KS Sink, PJ McLaughlin, JAT Wood, C Brown, P Fan, VK Vemuri, Y Pang, ...
Neuropsychopharmacology 33 (4), 946-955, 2008
1842008
Selective activation of cannabinoid CB2 receptors suppresses neuropathic nociception induced by treatment with the chemotherapeutic agent paclitaxel in rats
EJ Rahn, AM Zvonok, GA Thakur, AD Khanolkar, A Makriyannis, ...
Journal of Pharmacology and Experimental Therapeutics 327 (2), 584-591, 2008
1372008
CB1 cannabinoid receptor ligands
GA Thakur, SP Nikas, A Makriyannis
Mini reviews in medicinal chemistry 5 (7), 631-640, 2005
1332005
Positive allosteric modulation of cannabinoid receptor type 1 suppresses pathological pain without producing tolerance or dependence
RA Slivicki, Z Xu, PM Kulkarni, RG Pertwee, K Mackie, GA Thakur, ...
Biological psychiatry 84 (10), 722-733, 2018
1272018
Ligand-binding architecture of human CB2 cannabinoid receptor: evidence for receptor subtype-specific binding motif and modeling GPCR activation
Y Pei, RW Mercier, JK Anday, GA Thakur, AM Zvonok, D Hurst, ...
Chemistry & biology 15 (11), 1207-1219, 2008
1182008
Latest advances in cannabinoid receptor agonists
GA Thakur, R Tichkule, S Bajaj, A Makriyannis
Expert opinion on therapeutic patents 19 (12), 1647-1673, 2009
1162009
(-)-7′-Isothiocyanato-11-hydroxy-1′, 1′-dimethylheptylhexahydrocannabinol (AM841), a high-affinity electrophilic ligand, interacts covalently with a cysteine in helix six …
RP Picone, AD Khanolkar, W Xu, LA Ayotte, GA Thakur, DP Hurst, ...
Molecular pharmacology 68 (6), 1623-1635, 2005
1152005
Cannabilactones: a novel class of CB2 selective agonists with peripheral analgesic activity
AD Khanolkar, D Lu, M Ibrahim, RI Duclos, Jr, GA Thakur, TP Malan, Jr, ...
Journal of medicinal chemistry 50 (26), 6493-6500, 2007
1102007
Natural cannabinoids: templates for drug discovery
GA Thakur, RI Duclos Jr, A Makriyannis
Life sciences 78 (5), 454-466, 2005
1082005
Intrathecal cannabilactone CB2R agonist, AM1710, controls pathological pain and restores basal cytokine levels
JL Wilkerson, KR Gentry, EC Dengler, JA Wallace, AA Kerwin, LM Armijo, ...
PAIN® 153 (5), 1091-1106, 2012
1042012
A Novel Example of Metal-Mediated Aromatic Thiolation in a Ruthenium Complex. Crystal Structure of RuII (SC6H4N NC6H4N) 2
BK Santra, GA Thakur, P Ghosh, A Pramanik, GK Lahiri
Inorganic Chemistry 35 (10), 3050-3052, 1996
1041996
Mutation studies of Ser7. 39 and Ser2. 60 in the human CB1 cannabinoid receptor: evidence for a serine-induced bend in CB1 transmembrane helix 7
A Kapur, DP Hurst, D Fleischer, R Whitnell, GA Thakur, A Makriyannis, ...
Molecular pharmacology 71 (6), 1512-1524, 2007
1012007
Enantiospecific allosteric modulation of cannabinoid 1 receptor
RB Laprairie, PM Kulkarni, JR Deschamps, MEM Kelly, DR Janero, ...
ACS chemical neuroscience 8 (6), 1188-1203, 2017
972017
The analgesic-like properties of the alpha7 nAChR silent agonist NS6740 is associated with non-conducting conformations of the receptor
RL Papke, D Bagdas, AR Kulkarni, T Gould, SD AlSharari, GA Thakur, ...
Neuropharmacology 91, 34-42, 2015
962015
The Maintenance of Cisplatin- and Paclitaxel-Induced Mechanical and Cold Allodynia is Suppressed by Cannabinoid CB2 Receptor Activation and Independent of …
L Deng, J Guindon, VK Vemuri, GA Thakur, FA White, A Makriyannis, ...
Molecular pain 8, 1744-8069-8-71, 2012
962012
The Maintenance of Cisplatin- and Paclitaxel-Induced Mechanical and Cold Allodynia is Suppressed by Cannabinoid CB2 Receptor Activation and Independent of …
L Deng, J Guindon, VK Vemuri, GA Thakur, FA White, A Makriyannis, ...
Molecular pain 8, 1744-8069-8-71, 2012
962012
Polyamidoamine dendrimers-based nanomedicine for combination therapy with siRNA and chemotherapeutics to overcome multidrug resistance
J Pan, LP Mendes, M Yao, N Filipczak, S Garai, GA Thakur, C Sarisozen, ...
European Journal of Pharmaceutics and Biopharmaceutics 136, 18-28, 2019
952019
Adamantyl cannabinoids: a novel class of cannabinergic ligands
D Lu, Z Meng, GA Thakur, P Fan, J Steed, CL Tartal, DP Hurst, PH Reggio, ...
Journal of medicinal chemistry 48 (14), 4576-4585, 2005
912005
The α7 nicotinic receptor dual allosteric agonist and positive allosteric modulator GAT107 reverses nociception in mouse models of inflammatory and neuropathic pain
D Bagdas, JL Wilkerson, A Kulkarni, W Toma, S AlSharari, Z Gul, ...
British Journal of Pharmacology 173 (16), 2506-2520, 2016
782016
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