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Robert B Rawson
Robert B Rawson
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ER stress induces cleavage of membrane-bound ATF6 by the same proteases that process SREBPs
J Ye, RB Rawson, R Komuro, X Chen, UP Davé, R Prywes, MS Brown, ...
Molecular cell 6 (6), 1355-1364, 2000
21552000
Regulated intramembrane proteolysis: a control mechanism conserved from bacteria to humans
MS Brown, J Ye, RB Rawson, JL Goldstein
Cell 100 (4), 391-398, 2000
17002000
Sterol-regulated release of SREBP-2 from cell membranes requires two sequential cleavages, one within a transmembrane segment
J Sakai, EA Duncan, RB Rawson, X Hua, MS Brown, JL Goldstein
Cell 85 (7), 1037-1046, 1996
6731996
Complementation cloning of S2P, a gene encoding a putative metalloprotease required for intramembrane cleavage of SREBPs
RB Rawson, NG Zelenski, D Nijhawan, J Ye, J Sakai, MT Hasan, ...
Molecular cell 1 (1), 47-57, 1997
5881997
Molecular identification of the sterol-regulated luminal protease that cleaves SREBPs and controls lipid composition of animal cells
J Sakai, RB Rawson, PJ Espenshade, D Cheng, AC Seegmiller, ...
Molecular cell 2 (4), 505-514, 1998
5271998
Toward a molecular genetic analysis of spermatogenesis in Drosophila melanogaster: characterization of male-sterile mutants generated by single P element mutagenesis.
DH Castrillon, P Gönczy, S Alexander, R Rawson, CG Eberhart, ...
Genetics 135 (2), 489-505, 1993
4391993
The SREBP pathway—insights from Insigs and insects
RB Rawson
Nature reviews Molecular cell biology 4 (8), 631-640, 2003
4112003
Regulation of SREBP processing and membrane lipid production by phospholipids in Drosophila
IY Dobrosotskaya, AC Seegmiller, MS Brown, JL Goldstein, RB Rawson
Science 296 (5569), 879-883, 2002
3662002
Mutant mammalian cells as tools to delineate the sterol regulatory element-binding protein pathway for feedback regulation of lipid synthesis
JL Goldstein, RB Rawson, MS Brown
Archives of biochemistry and biophysics 397 (2), 139-148, 2002
3292002
The SREBP pathway in Drosophila: regulation by palmitate, not sterols
AC Seegmiller, I Dobrosotskaya, JL Goldstein, YK Ho, MS Brown, ...
Developmental cell 2 (2), 229-238, 2002
2192002
Failure to cleave sterol regulatory element-binding proteins (SREBPs) causes cholesterol auxotrophy in Chinese hamster ovary cells with genetic absence of SREBP cleavage …
RB Rawson, R DeBose-Boyd, JL Goldstein, MS Brown
Journal of Biological Chemistry 274 (40), 28549-28556, 1999
2011999
UbcD1, a Drosophila ubiquitin-conjugating enzyme required for proper telomere behavior.
G Cenci, RB Rawson, G Belloni, DH Castrillon, M Tudor, R Petrucci, ...
Genes & development 11 (7), 863-875, 1997
1621997
Dual roles for cholesterol in mammalian cells
F Xu, SD Rychnovsky, JD Belani, HH Hobbs, JC Cohen, RB Rawson
Proceedings of the National Academy of Sciences 102 (41), 14551-14556, 2005
1612005
Dual roles for cholesterol in mammalian cells
F Xu, SD Rychnovsky, JD Belani, HH Hobbs, JC Cohen, RB Rawson
Proceedings of the National Academy of Sciences 102 (41), 14551-14556, 2005
1612005
Membrane topology of S2P, a protein required for intramembranous cleavage of sterol regulatory element-binding proteins
NG Zelenski, RB Rawson, MS Brown, JL Goldstein
Journal of Biological Chemistry 274 (31), 21973-21980, 1999
1431999
COPI activity coupled with fatty acid biosynthesis is required for viral replication
S Cherry, A Kunte, H Wang, C Coyne, RB Rawson, N Perrimon
PLoS pathogens 2 (10), e102, 2006
1402006
Fatty acid auxotrophy in Drosophila larvae lacking SREBP
AS Kunte, KA Matthews, RB Rawson
Cell metabolism 3 (6), 439-448, 2006
1372006
Three mutations in sterol-sensing domain of SCAP block interaction with insig and render SREBP cleavage insensitive to sterols
D Yabe, ZP Xia, CM Adams, RB Rawson
Proceedings of the National Academy of Sciences 99 (26), 16672-16677, 2002
1272002
Isolation of cholesterol-requiring mutant Chinese hamster ovary cells with defects in cleavage of sterol regulatory element-binding proteins at site 1
RB Rawson, D Cheng, MS Brown, JL Goldstein
Journal of Biological Chemistry 273 (43), 28261-28269, 1998
1231998
The sterol regulatory element-binding protein pathway: control of lipid homeostasis through regulated intracellular transport
J Sakai, RB Rawson
Current opinion in lipidology 12 (3), 261-266, 2001
942001
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