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Giovanni Lentini
Giovanni Lentini
Professore di Chimica Farmaceutica
Dirección de correo verificada de uniba.it
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Citado por
Citado por
Año
The chemistry and pharmacology of citrus limonoids
R Gualdani, MM Cavalluzzi, G Lentini, S Habtemariam
Molecules 21 (11), 1530, 2016
1632016
Plant-derived anticancer agents: Lessons from the pharmacology of geniposide and its aglycone, genipin
S Habtemariam, G Lentini
Biomedicines 6 (2), 39, 2018
922018
Ligand efficiency metrics in drug discovery: The pros and cons from a practical perspective
MM Cavalluzzi, GF Mangiatordi, O Nicolotti, G Lentini
Expert opinion on drug discovery 12 (11), 1087-1104, 2017
802017
A mini-review on thalidomide: chemistry, mechanisms of action, therapeutic potential and anti-angiogenic properties in multiple myeloma
A Mercurio, G Adriani, A Catalano, A Carocci, L Rao, G Lentini, ...
Current medicinal chemistry 24 (25), 2736-2744, 2017
802017
Molecular determinants of mexiletine structure for potent and use-dependent block of skeletal muscle sodium channels
A De Luca, F Natuzzi, JF Desaphy, G Loni, G Lentini, C Franchini, ...
Molecular Pharmacology 57 (2), 268-277, 2000
672000
The therapeutic potential of rutin for diabetes: an update
S Habtemariam, G Lentini
Mini Reviews in Medicinal Chemistry 15 (7), 524-528, 2015
662015
Optically active mexiletine analogues as stereoselective blockers of voltage-gated Na+ channels
C Franchini, A Carocci, A Catalano, MM Cavalluzzi, F Corbo, G Lentini, ...
Journal of medicinal chemistry 46 (24), 5238-5248, 2003
662003
Phytochemical, Antioxidant and Anti‐α‐glucosidase Activity Evaluations of Bergenia cordifolia
M Roselli, G Lentini, S Habtemariam
Phytotherapy Research 26 (6), 908-914, 2012
642012
New N-(phenoxydecyl) phthalimide derivatives displaying potent inhibition activity towards α-glucosidase
R Pascale, A Carocci, A Catalano, G Lentini, A Spagnoletta, ...
Bioorganic & medicinal chemistry 18 (16), 5903-5914, 2010
592010
Stereospecific synthesis of mexiletine and related compounds: Mitsunobu versus Williamson reaction
A Carocci, A Catalano, F Corbo, A Duranti, R Amoroso, C Franchini, ...
Tetrahedron: Asymmetry 11 (17), 3619-3634, 2000
592000
Targeting the pregnane X receptor using microbial metabolite mimicry
Z Dvořák, F Kopp, CM Costello, JS Kemp, H Li, A Vrzalová, M Štěpánková, ...
EMBO molecular medicine 12 (4), e11621, 2020
552020
Old drug scaffold, new activity: thalidomide‐correlated compounds exert different effects on breast cancer cell growth and progression
D Iacopetta, A Carocci, MS Sinicropi, A Catalano, G Lentini, J Ceramella, ...
ChemMedChem 12 (5), 381-389, 2017
542017
Stereoselective effects of mexiletine enantiomers on sodium currents and excitability characteristics of adult skeletal muscle fibers
A De Luca, F Natuzzi, G Lentini, C Franchini, V Tortorella, ...
Naunyn-Schmiedeberg's archives of pharmacology 352, 653-661, 1995
531995
Evaluation of the antimyotonic activity of mexiletine and some new analogs on sodium currents of single muscle fibers and on the abnormal excitability of the myotonic ADR mouse
A De Luca, S Pierno, F Natuzzi, C Franchini, A Duranti, G Lentini, ...
Journal of Pharmacology and Experimental Therapeutics 282 (1), 93-100, 1997
481997
COVID-19, chloroquine repurposing, and cardiac safety concern: chirality might help
G Lentini, MM Cavalluzzi, S Habtemariam
Molecules 25 (8), 1834, 2020
472020
Inhibition of frog skeletal muscle sodium channels by newly synthesized chiral derivatives of mexiletine and tocainide
A De Luca, F Natuzzi, G Falcone, A Duranti, G Lentini, C Franchini, ...
Naunyn-Schmiedeberg's archives of pharmacology 356, 777-787, 1997
451997
Human ether-à-go-go-related potassium channel: Exploring SAR to improve drug design
MM Cavalluzzi, P Imbrici, R Gualdani, A Stefanachi, GF Mangiatordi, ...
Drug Discovery Today 25 (2), 344-366, 2020
412020
Design, synthesis, and pharmacological effects of structurally simple ligands for MT1 and MT2 melatonin receptors
A Carocci, A Catalano, A Lovece, G Lentini, A Duranti, V Lucini, ...
Bioorganic & medicinal chemistry 18 (17), 6496-6511, 2010
412010
Synthesis of (R)-,(S)-, and (RS)-hydroxymethylmexiletine, one of the major metabolites of mexiletine
MM Cavalluzzi, A Catalano, C Bruno, A Lovece, A Carocci, F Corbo, ...
Tetrahedron: Asymmetry 18 (20), 2409-2417, 2007
412007
Structure-based prediction of hERG-related cardiotoxicity: A benchmark study
TM Creanza, P Delre, N Ancona, G Lentini, M Saviano, GF Mangiatordi
Journal of Chemical Information and Modeling 61 (9), 4758-4770, 2021
392021
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Artículos 1–20