|Cooperative binding of transcription factors orchestrates reprogramming|
C Chronis, P Fiziev, B Papp, S Butz, G Bonora, S Sabri, J Ernst, K Plath
Cell 168 (3), 442-459. e20, 2017
|Long-range chromatin contacts in embryonic stem cells reveal a role for pluripotency factors and polycomb proteins in genome organization|
M Denholtz, G Bonora, C Chronis, E Splinter, W De Laat, J Ernst, ...
Cell stem cell 13 (5), 602-616, 2013
|Proteomic and genomic approaches reveal critical functions of H3K9 methylation and heterochromatin protein-1γ in reprogramming to pluripotency|
R Sridharan, M Gonzales-Cope, C Chronis, G Bonora, R McKee, ...
Nature cell biology 15 (7), 872-882, 2013
|CDKN2B methylation status and isolated chromosome 7 abnormalities predict responses to treatment with 5-azacytidine|
K Raj, A John, A Ho, C Chronis, S Khan, J Samuel, S Pomplun, ...
Leukemia 21 (9), 1937-1944, 2007
|Human naive pluripotent stem cells model X chromosome dampening and X inactivation|
A Sahakyan, R Kim, C Chronis, S Sabri, G Bonora, TW Theunissen, ...
Cell stem cell 20 (1), 87-101, 2017
|Human embryonic stem cells do not change their X inactivation status during differentiation|
S Patel, G Bonora, A Sahakyan, R Kim, C Chronis, J Langerman, ...
Cell reports 18 (1), 54-67, 2017
|Mechanistic insights into reprogramming to induced pluripotency|
R Ho, C Chronis, K Plath
Journal of cellular physiology 226 (4), 868-878, 2011
|Reducing MCM levels in human primary T cells during the G 0→ G 1 transition causes genomic instability during the first cell cycle|
SJ Orr, T Gaymes, D Ladon, C Chronis, B Czepulkowski, R Wang, ...
Oncogene 29 (26), 3803-3814, 2010
|Promoter-enhancer communication occurs primarily within insulated neighborhoods|
F Sun, C Chronis, M Kronenberg, XF Chen, T Su, FD Lay, K Plath, ...
Molecular cell 73 (2), 250-263. e5, 2019
|A functional assay for microRNA target identification and validation|
J Gäken, AM Mohamedali, J Jiang, F Malik, D Stangl, AE Smith, C Chronis, ...
Nucleic acids research 40 (10), e75-e75, 2012
|Mot1, Ino80C, and NC2 function coordinately to regulate pervasive transcription in yeast and mammals|
Y Xue, SK Pradhan, F Sun, C Chronis, N Tran, T Su, C Van, A Vashisht, ...
Molecular cell 67 (4), 594-607. e4, 2017
|Proteomic and protein interaction network analysis of human T lymphocytes during cell‐cycle entry|
SJ Orr, DR Boutz, R Wang, C Chronis, NC Lea, T Thayaparan, E Hamilton, ...
Molecular systems biology 8 (1), 573, 2012
|X chromosome dosage influences DNA methylation dynamics during reprogramming to mouse iPSCs|
V Pasque, R Karnik, C Chronis, P Petrella, J Langerman, G Bonora, ...
Stem cell reports 10 (5), 1537-1550, 2018
|Epigenetics of human T cells during the G0→ G1 transition|
AE Smith, C Chronis, M Christodoulakis, SJ Orr, NC Lea, NA Twine, ...
Genome research 19 (8), 1325-1337, 2009
|Loss of MECP2 leads to activation of P53 and neuronal senescence|
M Ohashi, E Korsakova, D Allen, P Lee, K Fu, BS Vargas, J Cinkornpumin, ...
Stem Cell Reports 10 (5), 1453-1463, 2018
|A protein assembly mediates Xist localization and gene silencing|
A Pandya-Jones, Y Markaki, J Serizay, T Chitiashvili, WRM Leon, ...
Nature 587 (7832), 145-151, 2020
|The BAF and PRC2 complex subunits Dpf2 and Eed antagonistically converge on Tbx3 to control ESC differentiation|
W Zhang, C Chronis, X Chen, H Zhang, R Spalinskas, M Pardo, L Chen, ...
Cell stem cell 24 (1), 138-152. e8, 2019
|Comparison of reprogramming factor targets reveals both species-specific and conserved mechanisms in early iPSC reprogramming|
K Fu, C Chronis, A Soufi, G Bonora, M Edwards, ST Smale, KS Zaret, ...
BMC genomics 19 (1), 1-13, 2018
|DNA methylation estimation using methylation-sensitive restriction enzyme bisulfite sequencing (MREBS)|
G Bonora, L Rubbi, M Morselli, F Ma, C Chronis, K Plath, M Pellegrini
PloS one 14 (4), e0214368, 2019
|An Xist-dependent protein assembly mediates Xist localization and gene silencing|
K Plath, DL Black, A Pandya-Jones, Y Markaki, J Serizay, T Chitiashvili, ...