NMR analysis demonstrates immunoglobulin G N-glycans are accessible and dynamic AW Barb, JH Prestegard Nature chemical biology 7 (3), 147-153, 2011 | 220 | 2011 |
C-terminal domain phosphatase-like family members (AtCPLs) differentially regulate Arabidopsis thaliana abiotic stress signaling, growth, and development H Koiwa, AW Barb, L Xiong, F Li, MG McCully, B Lee, I Sokolchik, J Zhu, ... Proceedings of the National Academy of Sciences 99 (16), 10893-10898, 2002 | 190 | 2002 |
The structural role of antibody N-glycosylation in receptor interactions GP Subedi, AW Barb Structure 23 (9), 1573-1583, 2015 | 185 | 2015 |
The immunoglobulin G1 N-glycan composition affects binding to each low affinity Fc γ receptor GP Subedi, AW Barb MAbs 8 (8), 1512-1524, 2016 | 175 | 2016 |
Mechanism and inhibition of LpxC: an essential zinc-dependent deacetylase of bacterial lipid A synthesis P Zhou, AW Barb Current pharmaceutical biotechnology 9 (1), 9-15, 2008 | 173 | 2008 |
NMR characterization of immunoglobulin G Fc glycan motion on enzymatic sialylation AW Barb, L Meng, Z Gao, RW Johnson, KW Moremen, JH Prestegard Biochemistry 51 (22), 4618-4626, 2012 | 130 | 2012 |
Inhibition of Lipid A Biosynthesis as the Primary Mechanism of CHIR-090 Antibiotic Activity in Escherichia coli AW Barb, AL McClerren, K Snehelatha, CM Reynolds, P Zhou, ... Biochemistry 46 (12), 3793-3802, 2007 | 128 | 2007 |
Structure of the deacetylase LpxC bound to the antibiotic CHIR-090: time-dependent inhibition and specificity in ligand binding AW Barb, L Jiang, CRH Raetz, P Zhou Proceedings of the National Academy of Sciences 104 (47), 18433-18438, 2007 | 120 | 2007 |
Species-specific and inhibitor-dependent conformations of LpxC: implications for antibiotic design CJ Lee, X Liang, X Chen, D Zeng, SH Joo, HS Chung, AW Barb, ... Chemistry & biology 18 (1), 38-47, 2011 | 107 | 2011 |
Molecular Validation of LpxC as an Antibacterial Drug Target in Pseudomonas aeruginosa KE Mdluli, PR Witte, T Kline, AW Barb, AL Erwin, BE Mansfield, ... Antimicrobial agents and Chemotherapy 50 (6), 2178-2184, 2006 | 100 | 2006 |
Branch-specific sialylation of IgG-Fc glycans by ST6Gal-I AW Barb, EK Brady, JH Prestegard Biochemistry 48 (41), 9705-9707, 2009 | 97 | 2009 |
High yield expression of recombinant human proteins with the transient transfection of HEK293 cells in suspension GP Subedi, RW Johnson, HA Moniz, KW Moremen, AW Barb JoVE (Journal of Visualized Experiments), e53568, 2015 | 93 | 2015 |
Antibody fucosylation lowers the FcγRIIIa/CD16a affinity by limiting the conformations sampled by the N162-glycan DJ Falconer, GP Subedi, AM Marcella, AW Barb ACS chemical biology 13 (8), 2179-2189, 2018 | 85 | 2018 |
Restricted motion of the conserved immunoglobulin G1 N-glycan is essential for efficient FcγRIIIa binding GP Subedi, QM Hanson, AW Barb Structure 22 (10), 1478-1488, 2014 | 84 | 2014 |
Immunoglobulin G1 Fc domain motions: implications for Fc engineering M Frank, RC Walker, WN Lanzilotta, JH Prestegard, AW Barb Journal of molecular biology 426 (8), 1799-1811, 2014 | 78 | 2014 |
Restricted processing of CD16a/Fc γ receptor IIIa N-glycans from primary human NK cells impacts structure and function KR Patel, JT Roberts, GP Subedi, AW Barb Journal of Biological Chemistry 293 (10), 3477-3489, 2018 | 75 | 2018 |
Multiple variables at the leukocyte cell surface impact Fc γ receptor-dependent mechanisms KR Patel, JT Roberts, AW Barb Frontiers in immunology 10, 440290, 2019 | 73 | 2019 |
A perspective on the structure and receptor binding properties of immunoglobulin G Fc QM Hanson, AW Barb Biochemistry 54 (19), 2931-2942, 2015 | 63 | 2015 |
A synopsis of recent developments defining how N-glycosylation impacts immunoglobulin G structure and function Y Yamaguchi, AW Barb Glycobiology 30 (4), 214-225, 2020 | 44 | 2020 |
CD16a with oligomannose-type N-glycans is the only “low-affinity” Fc γ receptor that binds the IgG crystallizable fragment with high affinity in vitro GP Subedi, AW Barb Journal of Biological Chemistry 293 (43), 16842-16850, 2018 | 44 | 2018 |