| Assessing the carcinogenic potential of low-dose exposures to chemical mixtures in the environment: the challenge ahead WH Goodson III, L Lowe, DO Carpenter, M Gilbertson, A Manaf Ali, ... Carcinogenesis 36 (Suppl_1), S254-S296, 2015 | 332 | 2015 |
| A Novel β Subunit Increases Rate of Inactivation of Specific Voltage-gated Potassium Channel α Subunits (∗) MJ Morales, RC Castellino, AL Crews, RL Rasmusson, HC Strauss Journal of Biological Chemistry 270 (11), 6272-6277, 1995 | 212 | 1995 |
| Medulloblastomas overexpress the p53-inactivating oncogene WIP1/PPM1D RC Castellino, M De Bortoli, X Lu, SH Moon, TA Nguyen, MA Shepard, ... Journal of neuro-oncology 86, 245-256, 2008 | 160 | 2008 |
| Mechanisms of Disease: the PI3K–Akt–PTEN signaling node—an intercept point for the control of angiogenesis in brain tumors RC Castellino, DL Durden Nature Clinical Practice Neurology 3 (12), 682-693, 2007 | 131 | 2007 |
| C‐type inactivation controls recovery in a fast inactivating cardiac K+ channel (Kv1. 4) expressed in Xenopus oocytes. RL Rasmusson, MJ Morales, RC Castellino, Y Zhang, DL Campbell, ... The Journal of Physiology 489 (3), 709-721, 1995 | 126 | 1995 |
| Response to bevacizumab, irinotecan, and temozolomide in children with relapsed medulloblastoma: a multi-institutional experience D Aguilera, C Mazewski, J Fangusaro, TJ MacDonald, RY McNall-Knapp, ... Child's nervous system 29, 589-596, 2013 | 94 | 2013 |
| Medulloblastoma outcome is adversely associated with overexpression of EEF1D, RPL30, and RPS20 on the long arm of chromosome 8 M De Bortoli, RC Castellino, XY Lu, J Deyo, LM Sturla, AM Adesina, ... BMC cancer 6, 1-13, 2006 | 87 | 2006 |
| The rationale for targeted therapies in medulloblastoma TJ MacDonald, D Aguilera, RC Castellino Neuro-oncology 16 (1), 9-20, 2014 | 73 | 2014 |
| Mechanisms of environmental chemicals that enable the cancer hallmark of evasion of growth suppression R Nahta, F Al-Mulla, R Al-Temaimi, A Amedei, R Andrade-Vieira, SN Bay, ... Carcinogenesis 36 (Suppl_1), S2-S18, 2015 | 72 | 2015 |
| Time-and voltage-dependent modulation of a Kv1. 4 channel by a beta-subunit (Kv beta 3) cloned from ferret ventricle RC Castellino, MJ Morales, HC Strauss, RL Rasmusson American Journal of Physiology-Heart and Circulatory Physiology 269 (1 …, 1995 | 66 | 1995 |
| Sunitinib induces PTEN expression and inhibits PDGFR signaling and migration of medulloblastoma cells TJ Abouantoun, RC Castellino, TJ MacDonald Journal of neuro-oncology 101, 215-226, 2011 | 59 | 2011 |
| Heterozygosity for Pten promotes tumorigenesis in a mouse model of medulloblastoma RC Castellino, BG Barwick, M Schniederjan, MC Buss, O Becher, ... PloS one 5 (5), e10849, 2010 | 58 | 2010 |
| Successful retreatment of a child with a refractory brainstem ganglioglioma with vemurafenib D Aguilera, A Janss, C Mazewski, RC Castellino, M Schniederjan, ... Pediatric Blood & Cancer 63 (3), 541-543, 2016 | 56 | 2016 |
| The WIP1 oncogene promotes progression and invasion of aggressive medulloblastoma variants MC Buss, M Remke, J Lee, K Gandhi, MJ Schniederjan, M Kool, ... Oncogene 34 (9), 1126-1140, 2015 | 56 | 2015 |
| Growth differentiation factor 15 mediates epithelial mesenchymal transition and invasion of breast cancers through IGF-1R-FoxM1 signaling BF Peake, SM Eze, L Yang, RC Castellino, R Nahta Oncotarget 8 (55), 94393, 2017 | 53 | 2017 |
| Overexpressed TP73 induces apoptosis in medulloblastoma RC Castellino, M De Bortoli, LL Lin, DG Skapura, JA Rajan, AM Adesina, ... BMC cancer 7, 1-16, 2007 | 53 | 2007 |
| Insulin-like Growth Factor-1 receptor signaling increases the invasive potential of Human Epidermal growth factor Receptor 2–overexpressing breast cancer cells via Src-focal … E Sanabria-Figueroa, SM Donnelly, KC Foy, MC Buss, RC Castellino, ... Molecular pharmacology 87 (2), 150-161, 2015 | 44 | 2015 |
| A novel role for extracellular signal-regulated kinase 5 and myocyte enhancer factor 2 in medulloblastoma cell death LM Sturla, CW Cowan, L Guenther, RC Castellino, JYH Kim, SL Pomeroy Cancer research 65 (13), 5683-5689, 2005 | 44 | 2005 |
| Clinical responses of patients with diffuse leptomeningeal glioneuronal tumors to chemotherapy D Aguilera, RC Castellino, A Janss, M Schniederjan, R McNall, ... Child's Nervous System 34, 329-334, 2018 | 41 | 2018 |
| Schedule-dependent activity of irinotecan plus BCNU against malignant glioma xenografts HS Friedman, RC Castellino, GB Elion, ST Keir, PJ Houghton, ... Cancer chemotherapy and pharmacology 45, 345-349, 2000 | 40 | 2000 |
