| p62/SQSTM1 is required for Parkin-induced mitochondrial clustering but not mitophagy; VDAC1 is dispensable for both D Narendra, LA Kane, DN Hauser, IM Fearnley, RJ Youle Autophagy 6 (8), 1090-1106, 2010 | 842 | 2010 |
| Dopamine: functions, signaling, and association with neurological diseases MO Klein, DS Battagello, AR Cardoso, DN Hauser, JC Bittencourt, ... Cellular and molecular neurobiology 39 (1), 31-59, 2019 | 813 | 2019 |
| Mitochondrial dysfunction and oxidative stress in Parkinson's disease and monogenic parkinsonism DN Hauser, TG Hastings Neurobiology of disease 51, 35-42, 2013 | 519 | 2013 |
| Unbiased screen for interactors of leucine-rich repeat kinase 2 supports a common pathway for sporadic and familial Parkinson disease A Beilina, IN Rudenko, A Kaganovich, L Civiero, H Chau, SK Kalia, ... Proceedings of the National Academy of Sciences 111 (7), 2626-2631, 2014 | 380 | 2014 |
| mRNA expression, splicing and editing in the embryonic and adult mouse cerebral cortex AA Dillman, DN Hauser, JR Gibbs, MA Nalls, MK McCoy, IN Rudenko, ... Nature neuroscience 16 (4), 499-506, 2013 | 150 | 2013 |
| The G2385R variant of leucine-rich repeat kinase 2 associated with Parkinson's disease is a partial loss-of-function mutation IN Rudenko, A Kaganovich, DN Hauser, A Beylina, R Chia, J Ding, ... Biochemical Journal 446 (1), 99-111, 2012 | 131 | 2012 |
| The road ahead for health and lifespan interventions M Gonzalez-Freire, A Diaz-Ruiz, D Hauser, J Martinez-Romero, L Ferrucci, ... Ageing research reviews 59, 101037, 2020 | 92 | 2020 |
| Dopamine quinone modifies and decreases the abundance of the mitochondrial selenoprotein glutathione peroxidase 4 DN Hauser, AA Dukes, AD Mortimer, TG Hastings Free Radical Biology and Medicine 65, 419-427, 2013 | 88 | 2013 |
| Proteomic analysis reveals co-ordinated alterations in protein synthesis and degradation pathways in LRRK2 knockout mice L Pellegrini, DN Hauser, Y Li, A Mamais, A Beilina, R Kumaran, A Wetzel, ... Human molecular genetics 27 (18), 3257-3271, 2018 | 61 | 2018 |
| Arsenite stress down-regulates phosphorylation and 14-3-3 binding of leucine-rich repeat kinase 2 (LRRK2), promoting self-association and cellular redistribution A Mamais, R Chia, A Beilina, DN Hauser, C Hall, PA Lewis, MR Cookson, ... Journal of Biological Chemistry 289 (31), 21386-21400, 2014 | 54 | 2014 |
| Hexokinases link DJ-1 to the PINK1/parkin pathway DN Hauser, A Mamais, MM Conti, CT Primiani, R Kumaran, AA Dillman, ... Molecular neurodegeneration 12, 1-17, 2017 | 53 | 2017 |
| The Effects of Variants in the Parkin, PINK1, and DJ-1 Genes along with Evidence for their Pathogenicity D N Hauser, C T Primiani, M R Cookson Current Protein and Peptide Science 18 (7), 702-714, 2017 | 25 | 2017 |
| Astrocytes in Parkinson’s disease and DJ-1 D Hauser, MR Cookson Journal of neurochemistry 117 (3), 357, 2011 | 22 | 2011 |
| The Polg mutator phenotype does not cause dopaminergic neurodegeneration in DJ-1-deficient mice DN Hauser, CT Primiani, RG Langston, R Kumaran, MR Cookson Eneuro 2 (1), 2015 | 20 | 2015 |
| Use of cysteine‐reactive cross‐linkers to probe conformational flexibility of human DJ‐1 demonstrates that Glu18 mutations are dimers J Prahlad, DN Hauser, NM Milkovic, MR Cookson, MA Wilson Journal of neurochemistry 130 (6), 839-853, 2014 | 19 | 2014 |
| Post-translational decrease in respiratory chain proteins in the Polg mutator mouse brain DN Hauser, AA Dillman, J Ding, Y Li, MR Cookson PLoS One 9 (4), e94646, 2014 | 17 | 2014 |
| Differences in stability, activity and mutation effects between human and mouse leucine-rich repeat kinase 2 RG Langston, IN Rudenko, R Kumaran, DN Hauser, A Kaganovich, ... Neurochemical research 44, 1446-1459, 2019 | 10 | 2019 |
| Generation of iPSC line from a Parkinson patient with PARK7 mutation and CRISPR-edited Gibco human episomal iPSC line to mimic PARK7 mutation MC Mazza, A Beilina, DA Roosen, D Hauser, MR Cookson Stem cell research 55, 102506, 2021 | 4 | 2021 |
| Longitudinal characterization of transcriptomic, functional, and morphological features in human iPSC-derived neurons and their application to investigate translational … G Robin, JC Evans, DN Hauser, P Wren, A Zembrzycki Frontiers in Aging Neuroscience 12, 576678, 2020 | 3 | 2020 |
| Dopamine Oxidation and Quinone Modification of Proteins: Mechanisms of Toxicity and Implications for Parkinson’s Disease TG Hastings, A Mortimer, D Hauser Catecholamine Research in the 21st Century, 122, 2014 | | 2014 |
Mark CooksonLaboratory of Neurogenetics, National Institute on Aging, National Institutes of HealthVerified email at mail.nih.gov
