| Poly (ADP-ribose) polymerases: homology, structural domains and functions. Novel therapeutical applications PA Nguewa, MA Fuertes, B Valladares, C Alonso, JM Pérez Progress in biophysics and molecular biology 88 (1), 143-172, 2005 | 200 | 2005 |
| Antitumor and antiangiogenic effect of the dual EGFR and HER-2 tyrosine kinase inhibitor lapatinib in a lung cancer model R Diaz, PA Nguewa, R Parrondo, C Perez-Stable, I Manrique, M Redrado, ... BMC cancer 10, 1-10, 2010 | 102 | 2010 |
| Programmed cell death in trypanosomatids: a way to maximize their biological fitness? PA Nguewa, MA Fuertes, B Valladares, C Alonso, JM Pérez Trends in parasitology 20 (8), 375-380, 2004 | 95 | 2004 |
| Thermosensitive hydrogels of poly (methyl vinyl ether-co-maleic anhydride)–Pluronic® F127 copolymers for controlled protein release E Moreno, J Schwartz, E Larrañeta, PA Nguewa, C Sanmartín, M Agüeros, ... International Journal of Pharmaceutics 459 (1-2), 1-9, 2014 | 87 | 2014 |
| Anticancer compounds as leishmanicidal drugs: challenges in chemotherapy and future perspectives JM Perez, MA Fuertes, PA Nguewa, J Castilla, C Alonso Current medicinal chemistry 15 (5), 433-439, 2008 | 83 | 2008 |
| Overexpression of TMPRSS4 in non-small cell lung cancer is associated with poor prognosis in patients with squamous histology L Larzabal, PA Nguewa, R Pio, D Blanco, B Sanchez, MJ Rodríguez, ... British journal of cancer 105 (10), 1608-1614, 2011 | 78 | 2011 |
| Novel heteroaryl selenocyanates and diselenides as potent antileishmanial agents Y Baquedano, V Alcolea, MÁ Toro, KJ Gutiérrez, P Nguewa, M Font, ... Antimicrobial agents and chemotherapy 60 (6), 3802-3812, 2016 | 77 | 2016 |
| Poly (ADP-ribose) polymerase-1 inhibitor 3-aminobenzamide enhances apoptosis induction by platinum complexes in cisplatin-resistant tumor cells PA Nguewa, MA Fuertes, V Cepeda, C Alonso, C Quevedo, M Soto, ... Medicinal Chemistry 2 (1), 47-53, 2006 | 75 | 2006 |
| Pentamidine is an antiparasitic and apoptotic drug that selectively modifies ubiquitin PA Nguewa, MA Fuertes, V Cepeda, S Iborra, J Carrión, B Valladares, ... Chemistry & biodiversity 2 (10), 1387-1400, 2005 | 72 | 2005 |
| The novel Akt inhibitor Palomid 529 (P529) enhances the effect of radiotherapy in prostate cancer R Diaz, PA Nguewa, JA Diaz-Gonzalez, E Hamel, O Gonzalez-Moreno, ... British journal of cancer 100 (6), 932-940, 2009 | 66 | 2009 |
| Identification of importin 8 (IPO8) as the most accurate reference gene for the clinicopathological analysis of lung specimens PA Nguewa, J Agorreta, D Blanco, MD Lozano, J Gomez-Roman, ... BMC Molecular Biology 9, 1-11, 2008 | 66 | 2008 |
| Inhibitor of differentiation-1 as a novel prognostic factor in NSCLC patients with adenocarcinoma histology and its potential contribution to therapy resistance M Ponz-Sarvisé, PA Nguewa, MJ Pajares, J Agorreta, MD Lozano, ... Clinical Cancer Research 17 (12), 4155-4166, 2011 | 61 | 2011 |
| Nanoparticles as multifunctional devices for the topical treatment of cutaneous leishmaniasis E Moreno, J Schwartz, C Fernandez, C Sanmartin, P Nguewa, JM Irache, ... Expert Opinion on Drug Delivery 11 (4), 579-597, 2014 | 58 | 2014 |
| Novel hybrid selenosulfonamides as potent antileishmanial agents Y Baquedano, E Moreno, S Espuelas, P Nguewa, M Font, KJ Gutierrez, ... European Journal of Medicinal Chemistry 74, 116-123, 2014 | 55 | 2014 |
| Innovative lead compounds and formulation strategies as newer kinetoplastid therapies S Espuelas, D Plano, P Nguewa, M Font, JA Palop, JM Irache, ... Current medicinal chemistry 19 (25), 4259-4288, 2012 | 54 | 2012 |
| The quinoline imidoselenocarbamate EI201 blocks the AKT/mTOR pathway and targets cancer stem cells leading to a strong antitumor activity E Ibanez, A Agliano, C Prior, P Nguewa, M Redrado, I Gonzalez-Zubeldia, ... Current medicinal chemistry 19 (18), 3031-3043, 2012 | 54 | 2012 |
| Pharmacological modulation of poly (ADP-ribose) polymerase-mediated cell death: exploitation in cancer chemotherapy PA Nguewa, MA Fuertes, C Alonso, JM Peréz Molecular pharmacology 64 (5), 1007-1014, 2003 | 53 | 2003 |
| Water soluble cationic trans-platinum complexes which induce programmed cell death in the protozoan parasite Leishmania infantum PA Nguewa, MA Fuertes, S Iborra, Y Najajreh, D Gibson, E Martínez, ... Journal of inorganic biochemistry 99 (3), 727-736, 2005 | 45 | 2005 |
| Topical treatment of L. major infected BALB/c mice with a novel diselenide chitosan hydrogel formulation J Schwartz, E Moreno, C Fernández, I Navarro-Blasco, PA Nguewa, ... European Journal of Pharmaceutical Sciences 62, 309-316, 2014 | 41 | 2014 |
| Sunitinib reduces tumor hypoxia and angiogenesis, and radiosensitizes prostate cancer stem‐like cells R Diaz, PA Nguewa, M Redrado, I Manrique, A Calvo The Prostate 75 (11), 1137-1149, 2015 | 40 | 2015 |
