Lucy Colwell
Lucy Colwell
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Protein 3D structure computed from evolutionary sequence variation
DS Marks, LJ Colwell, R Sheridan, TA Hopf, A Pagnani, R Zecchina, ...
PloS one 6 (12), e28766, 2011
Three-dimensional structures of membrane proteins from genomic sequencing
TA Hopf, LJ Colwell, R Sheridan, B Rost, C Sander, DS Marks
Cell 149 (7), 1607-1621, 2012
The interface of protein structure, protein biophysics, and molecular evolution
DA Liberles, SA Teichmann, I Bahar, U Bastolla, J Bloom, ...
Protein Science 21 (6), 769-785, 2012
A core subunit of Polycomb repressive complex 1 is broadly conserved in function but not primary sequence
LY Beh, LJ Colwell, NJ Francis
Proceedings of the National Academy of Sciences 109 (18), E1063-E1071, 2012
Charge as a selection criterion for translocation through the nuclear pore complex
LJ Colwell, MP Brenner, K Ribbeck
PLoS Comput Biol 6 (4), e1000747, 2010
The emergence of protein complexes: quaternary structure, dynamics and allostery
T Perica, JA Marsh, FL Sousa, E Natan, LJ Colwell, SE Ahnert, ...
Biochemical Society Transactions 40 (3), 475-491, 2012
Inferring interaction partners from protein sequences
AF Bitbol, RS Dwyer, LJ Colwell, NS Wingreen
Proceedings of the National Academy of Sciences 113 (43), 12180-12185, 2016
Protein sectors: statistical coupling analysis versus conservation
T Teşileanu, LJ Colwell, S Leibler
PLoS Comput Biol 11 (2), e1004091, 2015
Action potential initiation in the Hodgkin-Huxley model
LJ Colwell, MP Brenner
PLoS Comput Biol 5 (1), e1000265, 2009
Comparative analysis of nanobody sequence and structure data
LS Mitchell, LJ Colwell
Proteins: Structure, Function, and Bioinformatics 86 (7), 697-706, 2018
Statistical and machine learning approaches to predicting protein–ligand interactions
LJ Colwell
Current opinion in structural biology 49, 123-128, 2018
Predicting functionally informative mutations in Escherichia coli BamA using evolutionary covariance analysis
RS Dwyer, DP Ricci, LJ Colwell, TJ Silhavy, NS Wingreen
Genetics 195 (2), 443-455, 2013
Power law tails in phylogenetic systems
C Qin, LJ Colwell
Proceedings of the National Academy of Sciences 115 (4), 690-695, 2018
Predicting protein–ligand affinity with a random matrix framework
AA Lee, MP Brenner, LJ Colwell
Proceedings of the National Academy of Sciences 113 (48), 13564-13569, 2016
Analysis of nanobody paratopes reveals greater diversity than classical antibodies
LS Mitchell, LJ Colwell
Protein Engineering, Design and Selection 31 (7-8), 267-275, 2018
The role of protein-ligand contacts in allosteric regulation of the Escherichia coli catabolite activator protein
PD Townsend, TL Rodgers, LC Glover, HJ Korhonen, SA Richards, ...
Journal of Biological Chemistry 290 (36), 22225-22235, 2015
Computational approaches to therapeutic antibody design: established methods and emerging trends
RA Norman, F Ambrosetti, AMJJ Bonvin, LJ Colwell, S Kelm, S Kumar, ...
Briefings in Bioinformatics, 2019
Proline provides site-specific flexibility for in vivo collagen
WY Chow, CJ Forman, D Bihan, AM Puszkarska, R Rajan, DG Reid, ...
Scientific reports 8 (1), 1-13, 2018
Conservation weighting functions enable covariance analyses to detect functionally important amino acids
LJ Colwell, MP Brenner, AW Murray
PloS one 9 (11), e107723, 2014
Using attribution to decode binding mechanism in neural network models for chemistry
K McCloskey, A Taly, F Monti, MP Brenner, LJ Colwell
Proceedings of the National Academy of Sciences 116 (24), 11624-11629, 2019
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