Leo van Grunsven
Leo van Grunsven
Professor @ Vrije Universiteit Brussel
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Guidelines for the use and interpretation of assays for monitoring autophagy
DJ Klionsky, FC Abdalla, H Abeliovich, RT Abraham, A Acevedo-Arozena, ...
Autophagy 8 (4), 445-544, 2012
The two-handed E box binding zinc finger protein SIP1 downregulates E-cadherin and induces invasion
J Comijn, G Berx, P Vermassen, K Verschueren, L van Grunsven, ...
Molecular cell 7 (6), 1267-1278, 2001
Withdrawal of differentiation inhibitory activity/leukemia inhibitory factor up-regulates D-type cyclins and cyclin-dependent kinase inhibitors in mouse embryonic stem cells
P Savatier, H Lapillonne, LA Van Grunsven, BB Rudkin, J Samarut
Oncogene 12 (2), 309-322, 1996
A role for autophagy during hepatic stellate cell activation
LFR Thoen, ELM Guimarães, L Dollé, I Mannaerts, M Najimi, E Sokal, ...
Journal of hepatology 55 (6), 1353-1360, 2011
The Hippo pathway effector YAP controls mouse hepatic stellate cell activation
I Mannaerts, SB Leite, S Verhulst, S Claerhout, N Eysackers, LFR Thoen, ...
Journal of hepatology 63 (3), 679-688, 2015
Keratin 19: a key role player in the invasion of human hepatocellular carcinomas
O Govaere, M Komuta, J Berkers, B Spee, C Janssen, F de Luca, ...
Gut 63 (4), 674-685, 2014
Advanced glycation end products induce production of reactive oxygen species via the activation of NADPH oxidase in murine hepatic stellate cells
ELM Guimarães, C Empsen, A Geerts, LA van Grunsven
Journal of hepatology 52 (3), 389-397, 2010
Stellate cells, hepatocytes, and endothelial cells imprint the kupffer cell identity on monocytes colonizing the liver macrophage niche
J Bonnardel, W T’Jonck, D Gaublomme, R Browaeys, CL Scott, L Martens, ...
Immunity 51 (4), 638-654. e9, 2019
Liposome based systems for systemic siRNA delivery: stability in blood sets the requirements for optimal carrier design
K Buyens, SC De Smedt, K Braeckmans, J Demeester, L Peeters, ...
Journal of controlled release 158 (3), 362-370, 2012
Cooperation of Sp1 and p300 in the induction of the CDK inhibitor p21 WAF1/CIP1 during NGF-mediated neuronal differentiation
N Billon, D Carlisi, MB Datto, LA van Grunsven, A Watt, XF Wang, ...
Oncogene 18 (18), 2872-2882, 1999
Novel human hepatic organoid model enables testing of drug-induced liver fibrosis in vitro
SB Leite, T Roosens, A El Taghdouini, I Mannaerts, AJ Smout, M Najimi, ...
Biomaterials 78, 1-10, 2016
The biliary epithelium gives rise to liver progenitor cells
D Rodrigo‐Torres, S Affò, M Coll, O Morales‐Ibanez, C Millán, D Blaya, ...
Hepatology 60 (4), 1367-1377, 2014
FXR agonist obeticholic acid reduces hepatic inflammation and fibrosis in a rat model of toxic cirrhosis
L Verbeke, I Mannaerts, R Schierwagen, O Govaere, S Klein, ...
Scientific reports 6 (1), 1-12, 2016
Chronic administration of valproic acid inhibits activation of mouse hepatic stellate cells in vitro and in vivo
I Mannaerts, NR Nuytten, V Rogiers, K Vanderkerken, LA van Grunsven, ...
Hepatology 51 (2), 603-614, 2010
Interaction between Smad-interacting protein-1 and the corepressor C-terminal binding protein is dispensable for transcriptional repression of E-cadherin
LA van Grunsven, C Michiels, T Van de Putte, L Nelles, G Wuytens, ...
Journal of Biological Chemistry 278 (28), 26135-26145, 2003
Valproic acid attenuates proteinuria and kidney injury
K Van Beneden, C Geers, M Pauwels, I Mannaerts, D Verbeelen, ...
Journal of the American Society of Nephrology 22 (10), 1863-1875, 2011
Generation of hepatic stellate cells from human pluripotent stem cells enables in vitro modeling of liver fibrosis
M Coll, L Perea, R Boon, SB Leite, J Vallverdú, I Mannaerts, A Smout, ...
Cell stem cell 23 (1), 101-113. e7, 2018
Cdyl: a new transcriptional co‐repressor
C Caron, C Pivot‐Pajot, LA van Grunsven, E Col, C Lestrat, S Rousseaux, ...
EMBO reports 4 (9), 877-882, 2003
EpCAM and the biology of hepatic stem/progenitor cells
L Dollé, ND Theise, E Schmelzer, L Boulter, O Gires, LA van Grunsven
American Journal of Physiology-Gastrointestinal and Liver Physiology, 2015
Distinct biological properties of two RET isoforms activated by MEN 2A and MEN 2B mutations
M Rossel, A Pasini, S Chappius, O Geneste, L Fournier, I Schuffenecker, ...
Oncogene 14 (3), 265-275, 1997
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