| A diarylquinoline drug active on the ATP synthase of Mycobacterium tuberculosis K Andries, P Verhasselt, J Guillemont, HWH Göhlmann, JM Neefs, ... Science 307 (5707), 223-227, 2005 | 2062 | 2005 |
| Diarylquinolines are bactericidal for dormant mycobacteria as a result of disturbed ATP homeostasis A Koul, L Vranckx, N Dendouga, W Balemans, I Van den Wyngaert, ... Journal of Biological Chemistry 283 (37), 25273-25280, 2008 | 341 | 2008 |
| FABIA: factor analysis for bicluster acquisition S Hochreiter, U Bodenhofer, M Heusel, A Mayr, A Mitterecker, A Kasim, ... Bioinformatics 26 (12), 1520-1527, 2010 | 294 | 2010 |
| p53-independent regulation of p21Waf1/Cip1 expression and senescence by Chk2 CM Aliouat-Denis, N Dendouga, I Van den Wyngaert, H Goehlmann, ... Molecular cancer research 3 (11), 627-634, 2005 | 185 | 2005 |
| Delayed bactericidal response of Mycobacterium tuberculosis to bedaquiline involves remodelling of bacterial metabolism A Koul, L Vranckx, N Dhar, HWH Göhlmann, E Özdemir, JM Neefs, ... Nature communications 5 (1), 1-10, 2014 | 162 | 2014 |
| Alterations in mucosal immunity identified in the colon of patients with irritable bowel syndrome J Aerssens, M Camilleri, W Talloen, L Thielemans, HWH Göhlmann, ... Clinical Gastroenterology and Hepatology 6 (2), 194-205, 2008 | 145 | 2008 |
| I/NI-calls for the exclusion of non-informative genes: a highly effective filtering tool for microarray data W Talloen, DA Clevert, S Hochreiter, D Amaratunga, L Bijnens, S Kass, ... Bioinformatics 23 (21), 2897-2902, 2007 | 139 | 2007 |
| Alterations in expression of p11 and SERT in mucosal biopsy specimens of patients with irritable bowel syndrome M Camilleri, CN Andrews, AE Bharucha, PJ Carlson, I Ferber, D Stephens, ... Gastroenterology 132 (1), 17-25, 2007 | 132 | 2007 |
| Graphical exploration of gene expression data: a comparative study of three multivariate methods L Wouters, HW Göhlmann, L Bijnens, SU Kass, G Molenberghs, PJ Lewi Biometrics 59 (4), 1131-1139, 2003 | 99 | 2003 |
| Transcription profiles of the bacterium Mycoplasma pneumoniae grown at different temperatures J Weiner III, CU Zimmerman, HWH Göhlmann, R Herrmann Nucleic acids research 31 (21), 6306-6320, 2003 | 99 | 2003 |
| Gene expression studies using Affymetrix microarrays H Gohlmann, W Talloen CRC Press, 2009 | 97 | 2009 |
| Cloning of a second gene encoding 6-phosphofructo-2-kinase in yeast, and characterization of mutant strains without fructose-2, 6-bisphosphate E Boles, HWH Göhlmann, FK Zimmermann Molecular microbiology 20, 65-76, 1996 | 90 | 1996 |
| Using transcriptomics to guide lead optimization in drug discovery projects: Lessons learned from the QSTAR project B Verbist, G Klambauer, L Vervoort, W Talloen, Z Shkedy, O Thas, ... Drug discovery today 20 (5), 505-513, 2015 | 66 | 2015 |
| Genome‐wide copy number alterations detection in fresh frozen and matched FFPE samples using SNP 6.0 arrays M Tuefferd, A De Bondt, I Van Den Wyngaert, W Talloen, T Verbeke, ... Genes, Chromosomes and Cancer 47 (11), 957-964, 2008 | 64 | 2008 |
| Response prediction to a multitargeted kinase inhibitor in cancer cell lines and xenograft tumors using high-content tyrosine peptide arrays with a kinetic readout M Versele, W Talloen, C Rockx, T Geerts, B Janssen, T Lavrijssen, P King, ... Molecular cancer therapeutics 8 (7), 1846-1855, 2009 | 53 | 2009 |
| Identification and Complementation of Frameshift Mutations Associated with Loss of Cytadherence inMycoplasma pneumoniae M Fisseha, HWH Göhlmann, R Herrmann, DC Krause Journal of bacteriology 181 (14), 4404-4410, 1999 | 53 | 1999 |
| Molecular profiling of murine sensory neurons in the nodose and dorsal root ganglia labeled from the peritoneal cavity PJ Peeters, J Aerssens, R de Hoogt, A Stanisz, HW Gohlmann, K Hillsley, ... Physiological genomics 24 (3), 252-263, 2006 | 49 | 2006 |
| Testing for trends in dose-response microarray experiments: a comparison of several testing procedures, multiplicity and resampling-based inference D Lin, Z Shkedy, D Yekutieli, T Burzykowski, HWH Göhlmann, A De Bondt, ... Statistical applications in genetics and molecular biology 6 (1), 2007 | 44 | 2007 |
| A genetics-led approach defines the drug target landscape of 30 immune-related traits H Fang, H De Wolf, B Knezevic, KL Burnham, J Osgood, A Sanniti, ... Nature genetics 51 (7), 1082-1091, 2019 | 41 | 2019 |
| Alterations in the brain–gut axis underlying visceral chemosensitivity in Nippostrongylus brasiliensis-infected mice J Aerssens, K Hillsley, PJ Peeters, R De Hoogt, A Stanisz, JH Lin, ... Gastroenterology 132 (4), 1375-1387, 2007 | 41 | 2007 |
Willem TalloenAssociate Director, Janssen Pharmaceutcials groupVerified email at its.jnj.com
