| Prolonged oral cannabinoid administration prevents neuroinflammation, lowers β-amyloid levels and improves cognitive performance in Tg APP 2576 mice AM Martín-Moreno, B Brera, C Spuch, E Carro, L García-García, ... Journal of neuroinflammation 9, 1-15, 2012 | 260 | 2012 |
| Choroid plexus megalin is involved in neuroprotection by serum insulin-like growth factor I E Carro, C Spuch, JL Trejo, D Antequera, I Torres-Aleman Journal of Neuroscience 25 (47), 10884-10893, 2005 | 252 | 2005 |
| Megalin mediates the transport of leptin across the blood-CSF barrier MO Dietrich, C Spuch, D Antequera, I Rodal, JG de Yébenes, JA Molina, ... Neurobiology of aging 29 (6), 902-912, 2008 | 233 | 2008 |
| Liposomes for targeted delivery of active agents against neurodegenerative diseases (Alzheimer's disease and Parkinson's disease) C Spuch, C Navarro Journal of drug delivery 2011, 2011 | 199 | 2011 |
| Blockade of the insulin-like growth factor I receptor in the choroid plexus originates Alzheimer's-like neuropathology in rodents: new cues into the human disease? E Carro, JL Trejo, C Spuch, D Bohl, JM Heard, I Torres-Aleman Neurobiology of aging 27 (11), 1618-1631, 2006 | 168 | 2006 |
| The effect of encapsulated VEGF-secreting cells on brain amyloid load and behavioral impairment in a mouse model of Alzheimer’s disease C Spuch, D Antequera, A Portero, G Orive, RM Hernández, JA Molina, ... Biomaterials 31 (21), 5608-5618, 2010 | 145 | 2010 |
| New insights in the amyloid-Beta interaction with mitochondria C Spuch, S Ortolano, C Navarro Journal of aging research 2012, 2012 | 127 | 2012 |
| Leptin induces proliferation of neuronal progenitors and neuroprotection in a mouse model of Alzheimer's disease R Perez-Gonzalez, D Antequera, T Vargas, C Spuch, M Bolós, E Carro Journal of Alzheimer's Disease 24 (s2), 17-25, 2011 | 126 | 2011 |
| Cytokines dysregulation in schizophrenia: a systematic review of psychoneuroimmune relationship D Rodrigues-Amorim, T Rivera-Baltanas, C Spuch, HJ Caruncho, ... Schizophrenia research 197, 19-33, 2018 | 117 | 2018 |
| LRP-1 and LRP-2 receptors function in the membrane neuron. Trafficking mechanisms and proteolytic processing in Alzheimer's disease C Spuch, S Ortolano, C Navarro Frontiers in physiology 3, 269, 2012 | 117 | 2012 |
| Advances in the treatment of neurodegenerative disorders employing nanoparticles C Spuch, O Saida, C Navarro Recent patents on drug delivery & formulation 6 (1), 2-18, 2012 | 107 | 2012 |
| Aβ accumulation in choroid plexus is associated with mitochondrial-induced apoptosis T Vargas, C Ugalde, C Spuch, D Antequera, MJ Morán, MA Martín, ... Neurobiology of aging 31 (9), 1569-1581, 2010 | 95 | 2010 |
| Cytoplasmic gelsolin increases mitochondrial activity and reduces Aβ burden in a mouse model of Alzheimer's disease D Antequera, T Vargas, C Ugalde, C Spuch, JA Molina, I Ferrer, ... Neurobiology of disease 36 (1), 42-50, 2009 | 92 | 2009 |
| Hyperphagia and central mechanisms for leptin resistance during pregnancy ML Trujillo, C Spuch, E Carro, R Senaris Endocrinology 152 (4), 1355-1365, 2011 | 87 | 2011 |
| Megalin interacts with APP and the intracellular adapter protein FE65 in neurons X Alvira-Botero, R Pérez-Gonzalez, C Spuch, T Vargas, D Antequera, ... Molecular and Cellular Neuroscience 45 (3), 306-315, 2010 | 79 | 2010 |
| Ligand-independent signaling by disulfide-crosslinked dimers of the p75 neurotrophin receptor M Vilar, I Charalampopoulos, RS Kenchappa, A Reversi, ... Journal of cell science 122 (18), 3351-3357, 2009 | 78 | 2009 |
| A new tacrine–melatonin hybrid reduces amyloid burden and behavioral deficits in a mouse model of Alzheimer’s disease C Spuch, D Antequera, M Isabel Fernandez-Bachiller, ... Neurotoxicity research 17, 421-431, 2010 | 75 | 2010 |
| Important role of microglia in HIV-1 associated neurocognitive disorders and the molecular pathways implicated in its pathogenesis A Borrajo, C Spuch, MA Penedo, JM Olivares, RC Agís-Balboa Annals of Medicine 53 (1), 43-69, 2021 | 73 | 2021 |
| Schizophrenia: a review of potential biomarkers D Rodrigues-Amorim, T Rivera-Baltanás, M López, C Spuch, JM Olivares, ... Journal of psychiatric research 93, 37-49, 2017 | 68 | 2017 |
| Treatment of lysosomal storage diseases: recent patents and future strategies S Ortolano, I Vieitez, C Navarro, C Spuch Recent patents on endocrine, metabolic & immune drug discovery 8 (1), 9-25, 2014 | 68 | 2014 |
Daniela Rodrigues AmorimMSc, PhD, Picower Institute for Learning and Memory, Massachusetts Institute of Technology, USAVerified email at sapo.pt
