christopher sassetti
christopher sassetti
university of massachusetts
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Genes required for mycobacterial growth defined by high density mutagenesis
CM Sassetti, DH Boyd, EJ Rubin
Molecular microbiology 48 (1), 77-84, 2003
Genetic requirements for mycobacterial survival during infection
CM Sassetti, EJ Rubin
Proceedings of the National Academy of Sciences 100 (22), 12989-12994, 2003
High-resolution phenotypic profiling defines genes essential for mycobacterial growth and cholesterol catabolism
JE Griffin, JD Gawronski, MA DeJesus, TR Ioerger, BJ Akerley, ...
PLoS Pathog 7 (9), e1002251, 2011
Mycobacterial persistence requires the utilization of host cholesterol
AK Pandey, CM Sassetti
Proceedings of the National Academy of Sciences 105 (11), 4376-4380, 2008
Comprehensive identification of conditionally essential genes in mycobacteria
CM Sassetti, DH Boyd, EJ Rubin
Proceedings of the National Academy of Sciences 98 (22), 12712-12717, 2001
Nitric oxide controls the immunopathology of tuberculosis by inhibiting NLRP3 inflammasome–dependent processing of IL-1β
BB Mishra, VAK Rathinam, GW Martens, AJ Martinot, H Kornfeld, ...
Nature immunology 14 (1), 52-60, 2013
Mutually dependent secretion of proteins required for mycobacterial virulence
SM Fortune, A Jaeger, DA Sarracino, MR Chase, CM Sassetti, ...
Proceedings of the National Academy of Sciences 102 (30), 10676-10681, 2005
RNA secondary structure and binding sites for gag gene products in the 5'packaging signal of human immunodeficiency virus type 1.
J Clever, C Sassetti, TG Parslow
Journal of virology 69 (4), 2101-2109, 1995
Identification of podocalyxin-like protein as a high endothelial venule ligand for L-selectin: parallels to CD34
C Sassetti, K Tangemann, MS Singer, DB Kershaw, SD Rosen
The Journal of experimental medicine 187 (12), 1965-1975, 1998
NOD2, RIP2 and IRF5 play a critical role in the type I interferon response to Mycobacterium tuberculosis
AK Pandey, Y Yang, Z Jiang, SM Fortune, F Coulombe, MA Behr, ...
PLoS Pathog 5 (7), e1000500, 2009
NOD2 pathway activation by MDP or Mycobacterium tuberculosis infection involves the stable polyubiquitination of Rip2
Y Yang, C Yin, A Pandey, D Abbott, C Sassetti, MA Kelliher
Journal of Biological Chemistry 282 (50), 36223-36229, 2007
Increased NOD2-mediated recognition of N-glycolyl muramyl dipeptide
F Coulombe, M Divangahi, F Veyrier, L de Léséleuc, JL Gleason, Y Yang, ...
Journal of Experimental Medicine 206 (8), 1709-1716, 2009
The folate pathway is a target for resistance to the drug para‐aminosalicylic acid (PAS) in mycobacteria
J Rengarajan, CM Sassetti, V Naroditskaya, A Sloutsky, BR Bloom, ...
Molecular microbiology 53 (1), 275-282, 2004
Metabolic regulation of mycobacterial growth and antibiotic sensitivity
SH Baek, AH Li, CM Sassetti
PLoS Biol 9 (5), e1001065, 2011
Comprehensive essentiality analysis of the Mycobacterium tuberculosis genome via saturating transposon mutagenesis
MA DeJesus, ER Gerrick, W Xu, SW Park, JE Long, CC Boutte, EJ Rubin, ...
MBio 8 (1), 2017
Global assessment of genomic regions required for growth in Mycobacterium tuberculosis
YJ Zhang, TR Ioerger, C Huttenhower, JE Long, CM Sassetti, ...
PLoS Pathog 8 (9), e1002946, 2012
Cholesterol catabolism by Mycobacterium tuberculosis requires transcriptional and metabolic adaptations
JE Griffin, AK Pandey, SA Gilmore, V Mizrahi, JD Mckinney, CR Bertozzi, ...
Chemistry & biology 19 (2), 218-227, 2012
The normalcy of dormancy: common themes in microbial quiescence
ESC Rittershaus, SH Baek, CM Sassetti
Cell host & microbe 13 (6), 643-651, 2013
Characterization of mycobacterial virulence genes through genetic interaction mapping
SM Joshi, AK Pandey, N Capite, SM Fortune, EJ Rubin, CM Sassetti
Proceedings of the National Academy of Sciences 103 (31), 11760-11765, 2006
Identification of new drug targets and resistance mechanisms in Mycobacterium tuberculosis
TR Ioerger, T O’Malley, R Liao, KM Guinn, MJ Hickey, N Mohaideen, ...
PloS one 8 (9), e75245, 2013
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