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christopher sassetti
christopher sassetti
university of massachusetts
Dirección de correo verificada de umassmed.edu - Página principal
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Genes required for mycobacterial growth defined by high density mutagenesis
CM Sassetti, DH Boyd, EJ Rubin
Molecular microbiology 48 (1), 77-84, 2003
29742003
Genetic requirements for mycobacterial survival during infection
CM Sassetti, EJ Rubin
Proceedings of the National Academy of Sciences 100 (22), 12989-12994, 2003
15662003
High-resolution phenotypic profiling defines genes essential for mycobacterial growth and cholesterol catabolism
JE Griffin, JD Gawronski, MA DeJesus, TR Ioerger, BJ Akerley, ...
PLoS pathogens 7 (9), e1002251, 2011
11292011
Mycobacterial persistence requires the utilization of host cholesterol
AK Pandey, CM Sassetti
Proceedings of the National Academy of Sciences 105 (11), 4376-4380, 2008
11162008
Comprehensive identification of conditionally essential genes in mycobacteria
CM Sassetti, DH Boyd, EJ Rubin
Proceedings of the National Academy of Sciences 98 (22), 12712-12717, 2001
7372001
Nitric oxide controls the immunopathology of tuberculosis by inhibiting NLRP3 inflammasome–dependent processing of IL-1β
BB Mishra, VAK Rathinam, GW Martens, AJ Martinot, H Kornfeld, ...
Nature immunology 14 (1), 52-60, 2013
6192013
Comprehensive Essentiality Analysis of the Mycobacterium tuberculosis Genome via Saturating Transposon Mutagenesis
MA DeJesus, ER Gerrick, W Xu, SW Park, JE Long, CC Boutte, EJ Rubin, ...
MBio 8 (1), 10.1128/mbio. 02133-16, 2017
5302017
Mutually dependent secretion of proteins required for mycobacterial virulence
SM Fortune, A Jaeger, DA Sarracino, MR Chase, CM Sassetti, ...
Proceedings of the National Academy of Sciences 102 (30), 10676-10681, 2005
4842005
RNA secondary structure and binding sites for gag gene products in the 5'packaging signal of human immunodeficiency virus type 1
J Clever, C Sassetti, TG Parslow
Journal of virology 69 (4), 2101-2109, 1995
4441995
Programmable transcriptional repression in mycobacteria using an orthogonal CRISPR interference platform
JM Rock, FF Hopkins, A Chavez, M Diallo, MR Chase, ER Gerrick, ...
Nature microbiology 2 (4), 1-9, 2017
4382017
The normalcy of dormancy: common themes in microbial quiescence
ESC Rittershaus, SH Baek, CM Sassetti
Cell host & microbe 13 (6), 643-651, 2013
3542013
Identification of podocalyxin-like protein as a high endothelial venule ligand for L-selectin: parallels to CD34
C Sassetti, K Tangemann, MS Singer, DB Kershaw, SD Rosen
The Journal of experimental medicine 187 (12), 1965-1975, 1998
3421998
NOD2, RIP2 and IRF5 Play a Critical Role in the Type I Interferon Response to Mycobacterium tuberculosis
AK Pandey, Y Yang, Z Jiang, SM Fortune, F Coulombe, MA Behr, ...
PLoS pathogens 5 (7), e1000500, 2009
3352009
Metabolic regulation of mycobacterial growth and antibiotic sensitivity
SH Baek, AH Li, CM Sassetti
PLoS biology 9 (5), e1001065, 2011
3272011
Cholesterol catabolism by Mycobacterium tuberculosis requires transcriptional and metabolic adaptations
JE Griffin, AK Pandey, SA Gilmore, V Mizrahi, JD Mckinney, CR Bertozzi, ...
Chemistry & biology 19 (2), 218-227, 2012
2992012
Increased NOD2-mediated recognition of N-glycolyl muramyl dipeptide
F Coulombe, M Divangahi, F Veyrier, L de Léséleuc, JL Gleason, Y Yang, ...
Journal of Experimental Medicine 206 (8), 1709-1716, 2009
2832009
NOD2 pathway activation by MDP or Mycobacterium tuberculosis infection involves the stable polyubiquitination of Rip2
Y Yang, C Yin, A Pandey, D Abbott, C Sassetti, MA Kelliher
Journal of Biological Chemistry 282 (50), 36223-36229, 2007
2822007
Global Assessment of Genomic Regions Required for Growth in Mycobacterium tuberculosis
YJ Zhang, TR Ioerger, C Huttenhower, JE Long, CM Sassetti, ...
Public Library of Science 8 (9), e1002946, 2012
2772012
The folate pathway is a target for resistance to the drug para‐aminosalicylic acid (PAS) in mycobacteria
J Rengarajan, CM Sassetti, V Naroditskaya, A Sloutsky, BR Bloom, ...
Molecular microbiology 53 (1), 275-282, 2004
2682004
Identification of new drug targets and resistance mechanisms in Mycobacterium tuberculosis
TR Ioerger, T O’Malley, R Liao, KM Guinn, MJ Hickey, N Mohaideen, ...
PloS one 8 (9), e75245, 2013
2672013
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