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Alexis Kaushansky
Alexis Kaushansky
Center for Infectious Disease Research
Verified email at seattlechildrens.org - Homepage
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Cited by
Year
Complete Plasmodium falciparum liver-stage development in liver-chimeric mice
AM Vaughan, SA Mikolajczak, EM Wilson, M Grompe, A Kaushansky, ...
The Journal of clinical investigation 122 (10), 3618-3628, 2012
2392012
Plasmodium vivax liver stage development and hypnozoite persistence in human liver-chimeric mice
SA Mikolajczak, AM Vaughan, N Kangwanrangsan, W Roobsoong, ...
Cell host & microbe 17 (4), 526-535, 2015
2202015
Malaria parasites target the hepatocyte receptor EphA2 for successful host infection
A Kaushansky, AN Douglass, N Arang, V Vigdorovich, N Dambrauskas, ...
Science 350 (6264), 1089-1092, 2015
1352015
Suppression of host p53 is critical for Plasmodium liver-stage infection
A Kaushansky, SY Albert, LS Austin, SA Mikolajczak, AM Vaughan, ...
Cell reports 3 (3), 630-637, 2013
1092013
A next-generation genetically attenuated Plasmodium falciparum parasite created by triple gene deletion
SA Mikolajczak, V Lakshmanan, M Fishbaugher, N Camargo, A Harupa, ...
Molecular therapy 22 (9), 1707-1715, 2014
1042014
Model for In Vivo Assessment of Humoral Protection against Malaria Sporozoite Challenge by Passive Transfer of Monoclonal Antibodies and Immune Serum
BK Sack, JL Miller, AM Vaughan, A Douglass, A Kaushansky, ...
Infection and immunity 82 (2), 808-817, 2014
952014
Tarp regulates early Chlamydia-induced host cell survival through interactions with the human adaptor protein SHC1
A Mehlitz, S Banhart, AP Mäurer, A Kaushansky, AG Gordus, J Zielecki, ...
Journal of cell biology 190 (1), 143-157, 2010
912010
System-wide investigation of ErbB4 reveals 19 sites of Tyr phosphorylation that are unusually selective in their recruitment properties
A Kaushansky, A Gordus, BA Budnik, WS Lane, J Rush, G MacBeath
Chemistry & biology 15 (8), 808-817, 2008
912008
Quantifying protein–protein interactions in high throughput using protein domain microarrays
A Kaushansky, JE Allen, A Gordus, MA Stiffler, ES Karp, BH Chang, ...
Nature protocols 5 (4), 773-790, 2010
842010
Malaria parasite liver stages render host hepatocytes susceptible to mitochondria-initiated apoptosis
A Kaushansky, PG Metzger, AN Douglass, SA Mikolajczak, ...
Cell death & disease 4 (8), e762-e762, 2013
782013
Liver stage malaria infection is controlled by host regulators of lipid peroxidation
HS Kain, EKK Glennon, K Vijayan, N Arang, AN Douglass, CL Fortin, ...
Cell Death & Differentiation 27 (1), 44-54, 2020
692020
A molecular signature in blood reveals a role for p53 in regulating malaria-induced inflammation
TM Tran, R Guha, S Portugal, J Skinner, A Ongoiba, J Bhardwaj, M Jones, ...
Immunity 51 (4), 750-765. e10, 2019
692019
Linear combinations of docking affinities explain quantitative differences in RTK signaling
A Gordus, JA Krall, EM Beyer, A Kaushansky, A Wolf‐Yadlin, M Sevecka, ...
Molecular systems biology 5 (1), 235, 2009
672009
A quantitative study of the recruitment potential of all intracellular tyrosine residues on EGFR, FGFR1 and IGF1R
A Kaushansky, A Gordus, B Chang, J Rush, G MacBeath
Molecular Biosystems 4 (6), 643-653, 2008
672008
Next generation histology-directed imaging mass spectrometry driven by autofluorescence microscopy
NH Patterson, M Tuck, A Lewis, A Kaushansky, JL Norris, R Van de Plas, ...
Analytical chemistry 90 (21), 12404-12413, 2018
572018
Of men in mice: the success and promise of humanized mouse models for human malaria parasite infections
A Kaushansky, SA Mikolajczak, M Vignali, SHI Kappe
Cellular microbiology 16 (5), 602-611, 2014
552014
Opportunities for host-targeted therapies for malaria
EKK Glennon, S Dankwa, JD Smith, A Kaushansky
Trends in parasitology 34 (10), 843-860, 2018
542018
Phosphotyrosine signaling proteins that drive oncogenesis tend to be highly interconnected
G Koytiger, A Kaushansky, A Gordus, J Rush, PK Sorger, G MacBeath
Molecular & Cellular Proteomics 12 (5), 1204-1213, 2013
492013
Tyrosine-phosphorylated caveolin-1 blocks bacterial uptake by inducing Vav2-RhoA-mediated cytoskeletal rearrangements
JP Boettcher, M Kirchner, Y Churin, A Kaushansky, M Pompaiah, H Thorn, ...
PLoS biology 8 (8), e1000457, 2010
462010
Immunization with genetically attenuated P. falciparum parasites induces long-lived antibodies that efficiently block hepatocyte invasion by sporozoites
OC Finney, GJ Keitany, H Smithers, A Kaushansky, S Kappe, R Wang
Vaccine 32 (19), 2135-2138, 2014
432014
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