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Simon Koplev
Simon Koplev
Teichmann lab, Sanger Institute, Cambridge PhD
Verified email at cruk.cam.ac.uk
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Cited by
Year
Enrichr: a comprehensive gene set enrichment analysis web server 2016 update
MV Kuleshov, MR Jones, AD Rouillard, NF Fernandez, Q Duan, Z Wang, ...
Nucleic acids research 44 (W1), W90-W97, 2016
76832016
Multiancestry genome-wide association study of 520,000 subjects identifies 32 loci associated with stroke and stroke subtypes
R Malik, G Chauhan, M Traylor, M Sargurupremraj, Y Okada, A Mishra, ...
Nature genetics 50 (4), 524-537, 2018
11962018
The library of integrated network-based cellular signatures NIH program: system-level cataloging of human cells response to perturbations
AB Keenan, SL Jenkins, KM Jagodnik, S Koplev, E He, D Torre, Z Wang, ...
Cell systems 6 (1), 13-24, 2018
3882018
Macrophage Trafficking, Inflammatory Resolution, and Genomics in Atherosclerosis: JACC Macrophage in CVD Series (Part 2)
KJ Moore, S Koplev, EA Fisher, I Tabas, JLM Björkegren, AC Doran, ...
Journal of the American College of Cardiology 72 (18), 2181-2197, 2018
1662018
Unraveling tumor–immune heterogeneity in advanced ovarian cancer uncovers immunogenic effect of chemotherapy
A Jiménez-Sánchez, P Cybulska, KLV Mager, S Koplev, O Cast, ...
Nature Genetics 52 (6), 582-593, 2020
1512020
GWAS and colocalization analyses implicate carotid intima-media thickness and carotid plaque loci in cardiovascular outcomes
N Franceschini, C Giambartolomei, PS De Vries, C Finan, JC Bis, ...
Nature communications 9 (1), 5141, 2018
1382018
Clonally expanding smooth muscle cells promote atherosclerosis by escaping efferocytosis and activating the complement cascade
Y Wang, V Nanda, D Direnzo, J Ye, S Xiao, Y Kojima, KL Howe, KU Jarr, ...
Proceedings of the National Academy of Sciences 117 (27), 15818-15826, 2020
942020
Sex-stratified gene regulatory networks reveal female key driver genes of atherosclerosis involved in smooth muscle cell phenotype switching
RJG Hartman, K Owsiany, L Ma, S Koplev, K Hao, L Slenders, M Civelek, ...
Circulation 143 (7), 713-726, 2021
672021
A strategy for discovery of endocrine interactions with application to whole-body metabolism
MM Seldin, S Koplev, P Rajbhandari, L Vergnes, GM Rosenberg, Y Meng, ...
Cell metabolism 27 (5), 1138-1155. e6, 2018
662018
Contribution of gene regulatory networks to heritability of coronary artery disease
L Zeng, HA Talukdar, S Koplev, C Giannarelli, T Ivert, LM Gan, ...
Journal of the American College of Cardiology 73 (23), 2946-2957, 2019
492019
JCAD, a Gene at the 10p11 Coronary Artery Disease Locus, Regulates Hippo Signaling in Endothelial Cells
PD Jones, MA Kaiser, M Ghaderi Najafabadi, S Koplev, Y Zhao, ...
Arteriosclerosis, thrombosis, and vascular biology 38 (8), 1711-1722, 2018
462018
Histone deacetylase 9 promotes endothelial-mesenchymal transition and an unfavorable atherosclerotic plaque phenotype
L Lecce, Y Xu, B V’Gangula, N Chandel, V Pothula, A Caudrillier, ...
The Journal of clinical investigation 131 (15), 2021
452021
A mechanistic framework for cardiometabolic and coronary artery diseases
S Koplev, M Seldin, K Sukhavasi, R Ermel, S Pang, L Zeng, S Bankier, ...
Nature Cardiovascular Research 1 (1), 85-100, 2022
442022
An integrative multiomic network model links lipid metabolism to glucose regulation in coronary artery disease
AT Cohain, WT Barrington, DM Jordan, ND Beckmann, CA Argmann, ...
Nature communications 12 (1), 547, 2021
402021
Functional regulatory mechanism of smooth muscle cell-restricted LMOD1 coronary artery disease locus
V Nanda, T Wang, M Pjanic, B Liu, T Nguyen, LP Matic, U Hedin, ...
PLoS genetics 14 (11), e1007755, 2018
362018
Integration of pan-cancer transcriptomics with RPPA proteomics reveals mechanisms of epithelial-mesenchymal transition
S Koplev, K Lin, AB Dohlman, A Ma’ayan
PLoS computational biology 14 (1), e1005911, 2018
352018
CD90 identifies adventitial mesenchymal progenitor cells in adult human medium-and large-sized arteries
KC Michelis, A Nomura-Kitabayashi, L Lecce, O Franzén, S Koplev, Y Xu, ...
Stem Cell Reports 11 (1), 242-257, 2018
312018
MicroRNA-210, MicroRNA-331, and MicroRNA-7 Are Differentially Regulated in Treated HIV-1–Infected Individuals and Are Associated With Markers of Systemic Inflammation
V Ballegaard, U Ralfkiaer, KK Pedersen, M Hove, S Koplev, P Brćndstrup, ...
JAIDS Journal of Acquired Immune Deficiency Syndromes 74 (4), e104-e113, 2017
292017
Developing a framework for digital objects in the Big Data to Knowledge (BD2K) commons: Report from the Commons Framework Pilots workshop
KM Jagodnik, S Koplev, SL Jenkins, L Ohno-Machado, B Paten, ...
Journal of biomedical informatics 71, 49-57, 2017
282017
Functional and transcriptomic insights into pathogenesis of R9C phospholamban mutation using human induced pluripotent stem cell-derived cardiomyocytes
DK Ceholski, IC Turnbull, CW Kong, S Koplev, J Mayourian, PA Gorski, ...
Journal of molecular and cellular cardiology 119, 147-154, 2018
272018
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