Samy Meroueh
Samy Meroueh
Associate Professor of Biochemistry, Indiana University School of Medicine
Verified email at
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Bacterial resistance to β-lactam antibiotics: compelling opportunism, compelling opportunity
JF Fisher, SO Meroueh, S Mobashery
Chemical reviews 105 (2), 395-424, 2005
Three-dimensional structure of the bacterial cell wall peptidoglycan
SO Meroueh, KZ Bencze, D Hesek, M Lee, JF Fisher, TL Stemmler, ...
Proceedings of the National Academy of Sciences 103 (12), 4404-4409, 2006
A new genetic subgroup of chronic granulomatous disease with autosomal recessive mutations in p40phox and selective defects in neutrophil NADPH oxidase activity
JD Matute, AA Arias, NAM Wright, I Wrobel, C Waterhouse, XJ Li, ...
Blood 114 (15), 3309-3315, 2009
Suppression of inflammatory and neuropathic pain by uncoupling CRMP-2 from the presynaptic Ca 2+ channel complex
JM Brittain, DB Duarte, SM Wilson, W Zhu, C Ballard, PL Johnson, N Liu, ...
Nature medicine 17 (7), 822-829, 2011
Cell surface association of matrix metalloproteinase-9 (gelatinase B)
R Fridman, M Toth, I Chvyrkova, SO Meroueh, S Mobashery
Cancer and Metastasis Reviews 22 (2), 153-166, 2003
Ab initio QM/MM study of class A β-lactamase acylation: dual participation of Glu166 and Lys73 in a concerted base promotion of Ser70
SO Meroueh, JF Fisher, HB Schlegel, S Mobashery
Journal of the American Chemical Society 127 (44), 15397-15407, 2005
Direct dynamics simulations of collision-and surface-induced dissociation of N-protonated glycine. Shattering fragmentation
SO Meroueh, Y Wang, WL Hase
The Journal of Physical Chemistry A 106 (42), 9983-9992, 2002
Discovery and characterization of small molecules that target the GTPase Ral
C Yan, D Liu, L Li, MF Wempe, S Guin, M Khanna, J Meier, B Hoffman, ...
Nature 515 (7527), 443-447, 2014
Resistance to β-lactam antibiotics and its mediation by the sensor domain of the transmembrane BlaR signaling pathway in Staphylococcus aureus
D Golemi-Kotra, JY Cha, SO Meroueh, SB Vakulenko, S Mobashery
Journal of Biological Chemistry 278 (20), 18419-18425, 2003
Structural aspects for evolution of β-lactamases from penicillin-binding proteins
SO Meroueh, G Minasov, W Lee, BK Shoichet, S Mobashery
Journal of the American Chemical Society 125 (32), 9612-9618, 2003
A computational investigation of allostery in the catabolite activator protein
L Li, VN Uversky, AK Dunker, SO Meroueh
Journal of the American Chemical Society 129 (50), 15668-15676, 2007
Molecular structures and dynamics of the stepwise activation mechanism of a matrix metalloproteinase zymogen: challenging the cysteine switch dogma
G Rosenblum, S Meroueh, M Toth, JF Fisher, R Fridman, S Mobashery, ...
Journal of the American Chemical Society 129 (44), 13566-13574, 2007
The importance of a critical protonation state and the fate of the catalytic steps in class A β-lactamases and penicillin-binding proteins
D Golemi-Kotra, SO Meroueh, C Kim, SB Vakulenko, A Bulychev, ...
Journal of Biological Chemistry 279 (33), 34665-34673, 2004
A small molecule Inauhzin inhibits SIRT1 activity and suppresses tumour growth through activation of p53
Q Zhang, SX Zeng, Y Zhang, Y Zhang, D Ding, Q Ye, SO Meroueh, H Lu
EMBO molecular medicine 4 (4), 298-312, 2012
In silico docking and electrophysiological characterization of lacosamide binding sites on collapsin response mediator protein-2 identifies a pocket important in modulating …
Y Wang, JM Brittain, BW Jarecki, KD Park, SM Wilson, B Wang, R Hale, ...
Journal of Biological Chemistry 285 (33), 25296-25307, 2010
PDBcal: a comprehensive dataset for receptor–ligand interactions with three‐dimensional structures and binding thermodynamics from isothermal titration calorimetry
L Li, JJ Dantzer, J Nowacki, BJ O’Callaghan, SO Meroueh
Chemical biology & drug design 71 (6), 529-532, 2008
Support vector regression scoring of receptor–ligand complexes for rank-ordering and virtual screening of chemical libraries
L Li, B Wang, SO Meroueh
Journal of chemical information and modeling 51 (9), 2132-2138, 2011
Quest for selectivity in inhibition of matrix metalloproteinases
S Brown, SO Meroueh, R Fridman, S Mobashery
Current topics in medicinal chemistry 4 (12), 1227-1238, 2004
Neural mobilization reverses behavioral and cellular changes that characterize neuropathic pain in rats
FM Santos, JT Silva, AC Giardini, PA Rocha, APP Achermann, AS Alves, ...
Molecular pain 8, 1744-8069-8-57, 2012
X-ray crystal structure of the acylated β-lactam sensor domain of BlaR1 from Staphylococcus aureus and the mechanism of receptor activation for signal transduction
C Birck, JY Cha, J Cross, C Schulze-Briese, SO Meroueh, HB Schlegel, ...
Journal of the American Chemical Society 126 (43), 13945-13947, 2004
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