| ACC/AHA 2005 guideline update for the diagnosis and management of chronic heart failure in the adult: a report of the American College of Cardiology/American Heart Association … SA Hunt Journal of the American College of Cardiology 46 (6), e1-e82, 2005 | 8906* | 2005 |
| Effect of captopril on mortality and morbidity in patients with left ventricular dysfunction after myocardial infarction: results of the Survival and Ventricular Enlargement Trial MA Pfeffer, E Braunwald, LA Moyé, L Basta, EJ Brown Jr, TE Cuddy, ... New England journal of medicine 327 (10), 669-677, 1992 | 6881 | 1992 |
| The effect of carvedilol on morbidity and mortality in patients with chronic heart failure M Packer, MR Bristow, JN Cohn, WS Colucci, MB Fowler, EM Gilbert, ... New England Journal of Medicine 334 (21), 1349-1355, 1996 | 5633 | 1996 |
| Cardiac resynchronization in chronic heart failure WT Abraham, WG Fisher, AL Smith, DB Delurgio, AR Leon, E Loh, ... New England Journal of Medicine 346 (24), 1845-1853, 2002 | 5007 | 2002 |
| Effect of carvedilol on survival in severe chronic heart failure M Packer, AJS Coats, MB Fowler, HA Katus, H Krum, P Mohacsi, ... New England Journal of Medicine 344 (22), 1651-1658, 2001 | 4218 | 2001 |
| Angiotensin–neprilysin inhibition versus enalapril in heart failure JJV McMurray, M Packer, AS Desai, J Gong, MP Lefkowitz, AR Rizkala, ... N Engl J Med 371, 993-1004, 2014 | 4003 | 2014 |
| Bcl-2 antiapoptotic proteins inhibit Beclin 1-dependent autophagy S Pattingre, A Tassa, X Qu, R Garuti, XH Liang, N Mizushima, M Packer, ... Cell 122 (6), 927-939, 2005 | 3513 | 2005 |
| Elevated circulating levels of tumor necrosis factor in severe chronic heart failure B Levine, J Kalman, L Mayer, HM Fillit, M Packer New England Journal of Medicine 323 (4), 236-241, 1990 | 3106 | 1990 |
| Effect of oral milrinone on mortality in severe chronic heart failure M Packer, JR Carver, RJ Rodeheffer, RJ Ivanhoe, R DiBianco, SM Zeldis, ... New England Journal of Medicine 325 (21), 1468-1475, 1991 | 2478 | 1991 |
| The Seattle heart failure model WC Levy, D Mozaffarian, DT Linker, SC Sutradhar, SD Anker, AB Cropp, ... Circulation 113 (11), 1424-1433, 2006 | 1863 | 2006 |
| Spironolactone for heart failure with preserved ejection fraction et al Pitt B, Pfeffer MA, Assmann SF N Engl J Med 370 (15), 1383-92, 2014 | 1585 | 2014 |
| Comparative effects of low and high doses of the angiotensin-converting enzyme inhibitor, lisinopril, on morbidity and mortality in chronic heart failure M Packer, PA Poole-Wilson, PW Armstrong, JGF Cleland, JD Horowitz, ... Circulation 100 (23), 2312-2318, 1999 | 1487 | 1999 |
| Effect of amlodipine on morbidity and mortality in severe chronic heart failure M Packer, CM O'Connor, JK Ghali, ML Pressler, PE Carson, RN Belkin, ... New England Journal of Medicine 335 (15), 1107-1114, 1996 | 1462 | 1996 |
| Effect of amlodipine on morbidity and mortality in severe chronic heart failure M Packer, CM O'Connor, JK Ghali, ML Pressler, PE Carson, RN Belkin, ... New England Journal of Medicine 335 (15), 1107-1114, 1996 | 1462 | 1996 |
| Randomized, double-blind, placebo-controlled, pilot trial of infliximab, a chimeric monoclonal antibody to tumor necrosis factor-α, in patients with moderate-to-severe heart … ES Chung, M Packer, KH Lo, AA Fasanmade, JT Willerson Circulation 107 (25), 3133-3140, 2003 | 1427 | 2003 |
| Effect of carvedilol on the morbidity of patients with severe chronic heart failure: results of the carvedilol prospective randomized cumulative survival (COPERNICUS) study M Packer, MB Fowler, EB Roecker, AJS Coats, HA Katus, H Krum, ... Circulation 106 (17), 2194-2199, 2002 | 1394 | 2002 |
| The neurohormonal hypothesis: a theory to explain the mechanism of disease progression in heart failure M Packer Journal of the American College of Cardiology 20 (1), 248-254, 1992 | 1336 | 1992 |
| Targeted anticytokine therapy in patients with chronic heart failure: results of the Randomized Etanercept Worldwide Evaluation (RENEWAL) DL Mann, JJV McMurray, M Packer, K Swedberg, JS Borer, WS Colucci, ... Circulation 109 (13), 1594-1602, 2004 | 1192 | 2004 |
| Levosimendan vs dobutamine for patients with acute decompensated heart failure: the SURVIVE Randomized Trial A Mebazaa, MS Nieminen, M Packer, A Cohen-Solal, FX Kleber, ... Jama 297 (17), 1883-1891, 2007 | 1105 | 2007 |
| Sex differences in the management of coronary artery disease RM Steingart, M Packer, P Hamm, ME Coglianese, B Gersh, EM Geltman, ... New England Journal of Medicine 325 (4), 226-230, 1991 | 1092 | 1991 |
