| IFI16 is an innate immune sensor for intracellular DNA L Unterholzner, SE Keating, M Baran, KA Horan, SB Jensen, S Sharma, ... Nature immunology 11 (11), 997-1004, 2010 | 1807 | 2010 |
| Recognition of herpesviruses by the innate immune system SR Paludan, AG Bowie, KA Horan, KA Fitzgerald Nature Reviews Immunology 11 (2), 143-154, 2011 | 414 | 2011 |
| Single sample scoring of molecular phenotypes M Foroutan, DD Bhuva, R Lyu, K Horan, J Cursons, MJ Davis BMC bioinformatics 19, 1-10, 2018 | 316 | 2018 |
| The role of the inositol polyphosphate 5-phosphatases in cellular function and human disease LM Ooms, KA Horan, P Rahman, G Seaton, R Gurung, DS Kethesparan, ... Biochemical Journal 419 (1), 29-49, 2009 | 268 | 2009 |
| Listeria monocytogenes induces IFNβ expression through an IFI16‐, cGAS‐ and STING‐dependent pathway K Hansen, T Prabakaran, A Laustsen, SE Jørgensen, SH Rahbæk, ... The EMBO journal 33 (15), 1654-1666, 2014 | 264 | 2014 |
| Virus-cell fusion as a trigger of innate immunity dependent on the adaptor STING CK Holm, SB Jensen, MR Jakobsen, N Cheshenko, KA Horan, ... Nature immunology 13 (8), 737-743, 2012 | 255 | 2012 |
| Proteasomal degradation of herpes simplex virus capsids in macrophages releases DNA to the cytosol for recognition by DNA sensors KA Horan, K Hansen, MR Jakobsen, CK Holm, S Søby, L Unterholzner, ... The Journal of Immunology 190 (5), 2311-2319, 2013 | 223 | 2013 |
| Tracking the COVID-19 pandemic in Australia using genomics T Seemann, CR Lane, NL Sherry, S Duchene, A Gonçalves da Silva, ... Nature communications 11 (1), 1-9, 2020 | 185 | 2020 |
| TLR3 deficiency renders astrocytes permissive to herpes simplex virus infection and facilitates establishment of CNS infection in mice LS Reinert, L Harder, CK Holm, MB Iversen, KA Horan, ... The Journal of clinical investigation 122 (4), 1368-1376, 2012 | 184 | 2012 |
| Genomic HIV RNA induces innate immune responses through RIG-I-dependent sensing of secondary-structured RNA RK Berg, J Melchjorsen, J Rintahaka, E Diget, S Søby, KA Horan, ... PloS one 7 (1), e29291, 2012 | 164 | 2012 |
| Early innate recognition of herpes simplex virus in human primary macrophages is mediated via the MDA5/MAVS-dependent and MDA5/MAVS/RNA polymerase III-independent pathways J Melchjorsen, J Rintahaka, S Søby, KA Horan, A Poltajainen, ... Journal of virology 84 (21), 11350-11358, 2010 | 160 | 2010 |
| HSV infection induces production of ROS, which potentiate signaling from pattern recognition receptors: role for S-glutathionylation of TRAF3 and 6 R Gonzalez-Dosal, KA Horan, SH Rahbek, H Ichijo, ZJ Chen, JJ Mieyal, ... PLoS pathogens 7 (9), e1002250, 2011 | 133 | 2011 |
| Activation of autophagy by α-herpesviruses in myeloid cells is mediated by cytoplasmic viral DNA through a mechanism dependent on stimulator of IFN genes SB Rasmussen, KA Horan, CK Holm, AJ Stranks, TC Mettenleiter, ... The journal of immunology 187 (10), 5268-5276, 2011 | 127 | 2011 |
| Extracellular 2′-5′ oligoadenylate synthetase stimulates RNase L-independent antiviral activity: a novel mechanism of virus-induced innate immunity H Kristiansen, CA Scherer, M McVean, SP Iadonato, S Vends, ... Journal of virology 84 (22), 11898-11904, 2010 | 122 | 2010 |
| Evasion of innate cytosolic DNA sensing by a gammaherpesvirus facilitates establishment of latent infection C Sun, SA Schattgen, P Pisitkun, JP Jorgensen, AT Hilterbrand, LJ Wang, ... The Journal of Immunology 194 (4), 1819-1831, 2015 | 109 | 2015 |
| INPP5E regulates phosphoinositide-dependent cilia transition zone function JM Dyson, SE Conduit, SJ Feeney, S Hakim, T DiTommaso, AJ Fulcher, ... Journal of Cell Biology 216 (1), 247-263, 2017 | 105 | 2017 |
| Regulation of PI (3) K/Akt signalling and cellular transformation by inositol polyphosphate 4‐phosphatase‐1 I Ivetac, R Gurung, S Hakim, KA Horan, DA Sheffield, LC Binge, ... EMBO reports 10 (5), 487-493, 2009 | 84 | 2009 |
| Phosphatidylinositol 3-phosphate [PtdIns (3) P] is generated at thePlasma membrane by an inositol polyphosphate 5-phosphatase: endogenous PtdIns (3) P can promote GLUT4 … AM Kong, KA Horan, A Sriratana, CG Bailey, LJ Collyer, HH Nandurkar, ... Molecular and cellular biology 26 (16), 6065-6081, 2006 | 71 | 2006 |
| The inositol polyphosphate 5-phosphatases: traffic controllers, waistline watchers and tumour suppressors? MV Astle, KA Horan, LM Ooms, CA Mitchell Biochemical Society Symposia 74, 161-181, 2007 | 70 | 2007 |
| Structure guided prediction of Pyrazinamide resistance mutations in pncA M Karmakar, CHM Rodrigues, K Horan, JT Denholm, DB Ascher Scientific reports 10 (1), 1875, 2020 | 59 | 2020 |
