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Mingxia Gu
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Capillary cell-type specialization in the alveolus
A Gillich, F Zhang, CG Farmer, KJ Travaglini, SY Tan, M Gu, B Zhou, ...
Nature 586 (7831), 785-789, 2020
2492020
Patient-specific and genome-edited induced pluripotent stem cell–derived cardiomyocytes elucidate single-cell phenotype of Brugada syndrome
P Liang, K Sallam, H Wu, Y Li, I Itzhaki, P Garg, Y Zhang, V Termglichan, ...
Journal of the American College of Cardiology 68 (19), 2086-2096, 2016
2202016
In pulmonary arterial hypertension, reduced BMPR2 promotes endothelial-to-mesenchymal transition via HMGA1 and its target slug
RK Hopper, JRAJ Moonen, I Diebold, A Cao, CJ Rhodes, NF Tojais, ...
Circulation 133 (18), 1783-1794, 2016
2142016
Patient-specific iPSC-derived endothelial cells uncover pathways that protect against pulmonary hypertension in BMPR2 mutation carriers
M Gu, NY Shao, S Sa, D Li, V Termglinchan, M Ameen, I Karakikes, ...
Cell stem cell 20 (4), 490-504. e5, 2017
1982017
Epigenetic regulation of phosphodiesterases 2A and 3A underlies compromised β-adrenergic signaling in an iPSC model of dilated cardiomyopathy
H Wu, J Lee, LG Vincent, Q Wang, M Gu, F Lan, JM Churko, KI Sallam, ...
Cell stem cell 17 (1), 89-100, 2015
1932015
Genome editing of isogenic human induced pluripotent stem cells recapitulates long QT phenotype for drug testing
Y Wang, P Liang, F Lan, H Wu, L Lisowski, M Gu, S Hu, MA Kay, ...
Journal of the American College of Cardiology 64 (5), 451-459, 2014
1752014
Elafin reverses pulmonary hypertension via caveolin-1–dependent bone morphogenetic protein signaling
NP Nickel, E Spiekerkoetter, M Gu, CG Li, H Li, M Kaschwich, I Diebold, ...
American journal of respiratory and critical care medicine 191 (11), 1273-1286, 2015
1402015
Microfluidic single-cell analysis shows that porcine induced pluripotent stem cell–derived endothelial cells improve myocardial function by paracrine activation
M Gu, PK Nguyen, AS Lee, D Xu, S Hu, JR Plews, L Han, BC Huber, ...
Circulation research 111 (7), 882-893, 2012
1272012
Generation of quiescent cardiac fibroblasts from human induced pluripotent stem cells for in vitro modeling of cardiac fibrosis
H Zhang, L Tian, M Shen, C Tu, H Wu, M Gu, DT Paik, JC Wu
Circulation research 125 (5), 552-566, 2019
1212019
Intrinsic endocardial defects contribute to hypoplastic left heart syndrome
Y Miao, L Tian, M Martin, SL Paige, FX Galdos, J Li, A Klein, H Zhang, ...
Cell stem cell 27 (4), 574-589. e8, 2020
1112020
Activation of integrin α5 mediated by flow requires its translocation to membrane lipid rafts in vascular endothelial cells
X Sun, Y Fu, M Gu, L Zhang, D Li, H Li, S Chien, JYJ Shyy, Y Zhu
Proceedings of the National Academy of Sciences 113 (3), 769-774, 2016
1092016
RNA sequencing analysis detection of a novel pathway of endothelial dysfunction in pulmonary arterial hypertension
CJ Rhodes, H Im, A Cao, JK Hennigs, L Wang, S Sa, PI Chen, NP Nickel, ...
American journal of respiratory and critical care medicine 192 (3), 356-366, 2015
892015
Induced pluripotent stem cell model of pulmonary arterial hypertension reveals novel gene expression and patient specificity
S Sa, M Gu, J Chappell, NY Shao, M Ameen, KAT Elliott, D Li, F Grubert, ...
American journal of respiratory and critical care medicine 195 (7), 930-941, 2017
852017
Remodeling of active endothelial enhancers is associated with aberrant gene-regulatory networks in pulmonary arterial hypertension
A Reyes-Palomares, M Gu, F Grubert, I Berest, S Sa, M Kasowski, ...
Nature communications 11 (1), 1673, 2020
622020
A novel mechanism of γ/δ T-lymphocyte and endothelial activation by shear stress: the role of ecto-ATP synthase β chain
Y Fu, Y Hou, C Fu, M Gu, C Li, W Kong, X Wang, JYJ Shyy, Y Zhu
Circulation research 108 (4), 410-417, 2011
582011
Upregulation of human endogenous retrovirus-K is linked to immunity and inflammation in pulmonary arterial hypertension
T Saito, K Miyagawa, SY Chen, R Tamosiuniene, L Wang, O Sharpe, ...
Circulation 136 (20), 1920-1935, 2017
542017
BMP10 signaling promotes the development of endocardial cells from human pluripotent stem cell-derived cardiovascular progenitors
AA Mikryukov, A Mazine, B Wei, D Yang, Y Miao, M Gu, GM Keller
Cell Stem Cell 28 (1), 96-111. e7, 2021
532021
Pravastatin reverses obesity-induced dysfunction of induced pluripotent stem cell-derived endothelial cells via a nitric oxide-dependent mechanism
M Gu, NM Mordwinkin, NG Kooreman, J Lee, H Wu, S Hu, JM Churko, ...
European heart journal 36 (13), 806-816, 2015
512015
Efficient differentiation of human pluripotent stem cells to endothelial cells
M Gu
Current protocols in human genetics 98 (1), e64, 2018
482018
Endogenous retrovirus-derived lncRNA BANCR promotes cardiomyocyte migration in humans and non-human primates
KD Wilson, M Ameen, H Guo, OJ Abilez, L Tian, MR Mumbach, S Diecke, ...
Developmental cell 54 (6), 694-709. e9, 2020
432020
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