Joey Orpilla
TítuloCitado porAño
Neoadjuvant anti-PD-1 immunotherapy promotes a survival benefit with intratumoral and systemic immune responses in recurrent glioblastoma
TF Cloughesy, AY Mochizuki, JR Orpilla, W Hugo, AH Lee, TB Davidson, ...
Nature medicine 25 (3), 477, 2019
592019
PD-1 blockade enhances the vaccination-induced immune response in glioma
JP Antonios, H Soto, RG Everson, J Orpilla, D Moughon, N Shin, ...
JCI insight 1 (10), 2016
562016
Immunosuppressive tumor-infiltrating myeloid cells mediate adaptive immune resistance via a PD-1/PD-L1 mechanism in glioblastoma
JP Antonios, H Soto, RG Everson, D Moughon, JR Orpilla, NP Shin, ...
Neuro-oncology 19 (6), 796-807, 2017
552017
Detection of immune responses after immunotherapy in glioblastoma using PET and MRI
JP Antonios, H Soto, RG Everson, DL Moughon, AC Wang, J Orpilla, ...
Proceedings of the National Academy of Sciences 114 (38), 10220-10225, 2017
232017
Expression of PD-1 by T cells in malignant glioma patients reflects exhaustion and activation
TB Davidson, A Lee, M Hsu, S Sedighim, J Orpilla, J Treger, M Mastall, ...
Clinical Cancer Research 25 (6), 1913-1922, 2019
42019
Phase IIa clinical trial evaluating dendritic cell vaccine for the treatment of low-grade gliomas
D Moughon, R Everson, S Odesa, H Soto, E Billingslea-Yoon, S Sedighim, ...
NEURO-ONCOLOGY 18, 25-25, 2016
42016
ATIM-12. NEOADJUVANT ANTI-PD-1 IMMUNOTHERAPY PROMOTES INTRATUMORAL AND SYSTEMIC IMMUNE RESPONSES IN RECURRENT GLIOBLASTOMA: AN IVY CONSORTIUM TRIAL
R Prins, A Mochizuki, J Orpilla, A Lee, T Davidson, S Gaffey, C Sanders, ...
Neuro-Oncology 20 (suppl_6), vi3-vi3, 2018
22018
ATIM-25. neoadjuvant PD-1 antibody blockade is associated with focal upregulation of PD-L1 and CD8 T cell infiltrate in recurrent glioblastoma
J Orpilla, A Mochizuki, J Reynoso, N Akkad, A Lee, T Davidson, L Liau, ...
Neuro-Oncology 20 (Suppl 6), vi6, 2018
22018
PROTEIN MICROARRAY ANALYSIS OF GLIOBLASTOMA PATIENT SERA BEFORE AND AFTER DENDRITIC CELL VACCINATION
A Tucker, R Everson, J Orpilla, H Soto, F Yuan, L Liau, R Prins
NEURO-ONCOLOGY 18, 25-25, 2016
12016
TMIC-06. MYELOID POPULATIONS AND THE EFFECT OF NEOADJUVANT PD-1 INHIBITION IN THE GLIOBLASTOMA MICROENVIRONMENT: A SURFACEOMIC AND TRANSCRIPTOMIC DISSECTION AT THE SINGLE-CELL …
A Mochizuki, A Lee, J Orpilla, J Kienzler, M Galvez, F Chow, T Davidson, ...
Neuro-Oncology 21 (Supplement_6), vi248-vi248, 2019
2019
IMMU-33. IMMUNE PROFILING REVEALS INHIBITORY MACROPHAGES AND A DISTINCT SPATIAL DISTRIBUTION OF IMMUNE CELLS IN DIFFERENT TYPES OF BRAIN METASTASES
J Kienzler, J Reynoso, G Owens, J Orpilla, A Lee, A Mochizuki, WH Yong, ...
Neuro-Oncology 21 (Supplement_6), vi126-vi126, 2019
2019
IMMU-50. SYSTEMIC ADOPTIVE TRANSFER IMMUNOTHERAPY WITH TCR-TRANSDUCED T-CELLS TARGETING NY-ESO-1 FOR MENINGIOMA
M Sun, J Orpilla, E Contreras, J Treger, D Molaie, J Tsang, J Antonios, ...
Neuro-Oncology 21 (Supplement_6), vi129-vi130, 2019
2019
IMMU-28. HIGH-DIMENSIONAL SINGLE CELL CHARACTERIZATION OF THE SYSTEMIC INFLUENCE OF NEOADJUVANT PD-1 BLOCKADE IN PATIENTS WITH RECURRENT GLIOBLASTOMA
A Mochizuki, J Orpilla, A Lee, A Garcia, L Liau, T Cloughesy, R Prins
Neuro-Oncology 20 (suppl_6), vi127-vi127, 2018
2018
IMMU-37. VEMURAFENIB ENHANCES THE CYTOTOXICITY OF NY-ESO-1 TCR ENGINEERED T-CELLS FOR BRAF MUTANT BRAIN TUMORS
J Bethel, J Aliche, J Orpilla, H Soto, R Everson, T Davidson, A Wang, ...
Neuro-Oncology 20 (Suppl 6), vi129, 2018
2018
Nimg-36. Delineation Of Immune Responses After Immunotherapy In Glioblastoma Using Pet And Mri
H Soto, J Antonios, R Everson, D Moughon, A Wang, J Orpilla, C Radu, ...
Neuro-Oncology 19 (Suppl 6), vi149, 2017
2017
SUBTYPE-SPECIFIC CELLULAR COMPOSITION OF THE GLIOBLASTOMA MICROENVIRONMENT
J Antonios, H Soto, R Everson, J Orpilla, N Shin, D Moughon, S Sedighim, ...
NEURO-ONCOLOGY 18, 203-203, 2016
2016
TUMOR LYSATE-PULSED DC VACCINATION INDUCES NEOANTIGEN-SPECIFIC T CELL RESPONSES
R Everson, N Shin, J Antonios, H Soto, A Tucker, J Zaretsky, J Orpilla, ...
NEURO-ONCOLOGY 18, 99-99, 2016
2016
TMIC-18. ROLE OF MICROGLIA IN THE EARLY STEPS OF THE BRAIN METASTATIC CASCADE
A Berghoff, M Feinauer, G Solecki, J Grosch, M Osswald, B Gil, D Wilhelm, ...
Neuro-Oncology 18 (suppl_6), vi203-vi204, 2016
2016
NON-INVASIVE IMMUNE MONITORING FOLLOWING DC VACCINATION EFFECTIVELY DELINEATES IMMUNE RESPONSES IN GLIOBLASTOMA
J Antonios, H Soto, R Everson, J Orpilla, N Shin, D Nathanson, R Harris, ...
NEURO-ONCOLOGY 18, 92-92, 2016
2016
Glioma-infiltrating iAPCs mediate T cell recruitment to and activation in the tumor microenvironment
JP Antonios, H Soto, J Orpilla, N Shin, R Everson, R Prins, L Liau
JOURNAL OF NEUROSURGERY 124 (4), A1147-A1148, 2016
2016
El sistema no puede realizar la operación en estos momentos. Inténtalo de nuevo más tarde.
Artículos 1–20