| Neoadjuvant anti-PD-1 immunotherapy promotes a survival benefit with intratumoral and systemic immune responses in recurrent glioblastoma TF Cloughesy, AY Mochizuki, JR Orpilla, W Hugo, AH Lee, TB Davidson, ... Nature medicine 25 (3), 477-486, 2019 | 1092 | 2019 |
| Immunosuppressive tumor-infiltrating myeloid cells mediate adaptive immune resistance via a PD-1/PD-L1 mechanism in glioblastoma JP Antonios, H Soto, RG Everson, D Moughon, JR Orpilla, NP Shin, ... Neuro-oncology 19 (6), 796-807, 2017 | 188 | 2017 |
| PD-1 blockade enhances the vaccination-induced immune response in glioma JP Antonios, H Soto, RG Everson, J Orpilla, D Moughon, N Shin, ... JCI insight 1 (10), 2016 | 141 | 2016 |
| Neoadjuvant PD-1 blockade induces T cell and cDC1 activation but fails to overcome the immunosuppressive tumor associated macrophages in recurrent glioblastoma AH Lee, L Sun, AY Mochizuki, JG Reynoso, J Orpilla, F Chow, JC Kienzler, ... Nature communications 12 (1), 6938, 2021 | 106 | 2021 |
| Detection of immune responses after immunotherapy in glioblastoma using PET and MRI JP Antonios, H Soto, RG Everson, DL Moughon, AC Wang, J Orpilla, ... Proceedings of the National Academy of Sciences 114 (38), 10220-10225, 2017 | 94 | 2017 |
| Expression of PD-1 by T cells in malignant glioma patients reflects exhaustion and activation TB Davidson, A Lee, M Hsu, S Sedighim, J Orpilla, J Treger, M Mastall, ... Clinical Cancer Research 25 (6), 1913-1922, 2019 | 64 | 2019 |
| Simultaneous quantification of perfusion, permeability, and leakage effects in brain gliomas using dynamic spin-and-gradient-echo echoplanar imaging MRI F Sanvito, C Raymond, NS Cho, J Yao, A Hagiwara, J Orpilla, LM Liau, ... European Radiology, 1-15, 2023 | 4 | 2023 |
| ATIM-12. NEOADJUVANT ANTI-PD-1 IMMUNOTHERAPY PROMOTES INTRATUMORAL AND SYSTEMIC IMMUNE RESPONSES IN RECURRENT GLIOBLASTOMA: AN IVY CONSORTIUM TRIAL R Prins, A Mochizuki, J Orpilla, A Lee, T Davidson, S Gaffey, C Sanders, ... Neuro-oncology 20 (suppl_6), vi3-vi3, 2018 | 3 | 2018 |
| ATIM-25. neoadjuvant PD-1 antibody blockade is associated with focal upregulation of PD-L1 and CD8 T cell infiltrate in recurrent glioblastoma J Orpilla, A Mochizuki, J Reynoso, N Akkad, A Lee, T Davidson, L Liau, ... Neuro-oncology 20 (Suppl 6), vi6, 2018 | 2 | 2018 |
| Dendritic cell vaccination is effective against H3. 3G34R mutant glioblastoma in a novel syngeneic genetically engineered mouse model S Peeters, G Owens, MZ Sun, A Lee, JC Kienzler, J Orpilla, E Contreras, ... Neurosurgery 67, 2020 | 1 | 2020 |
| TMIC-06. MYELOID POPULATIONS AND THE EFFECT OF NEOADJUVANT PD-1 INHIBITION IN THE GLIOBLASTOMA MICROENVIRONMENT: A SURFACEOMIC AND TRANSCRIPTOMIC DISSECTION AT THE SINGLE-CELL … A Mochizuki, A Lee, J Orpilla, J Kienzler, M Galvez, F Chow, T Davidson, ... Neuro-oncology 21 (Supplement_6), vi248-vi248, 2019 | 1 | 2019 |
| IMMU-50. SYSTEMIC ADOPTIVE TRANSFER IMMUNOTHERAPY WITH TCR-TRANSDUCED T-CELLS TARGETING NY-ESO-1 FOR MENINGIOMA M Sun, J Orpilla, E Contreras, J Treger, D Molaie, J Tsang, J Antonios, ... Neuro-Oncology 21 (Supplement_6), vi129-vi130, 2019 | 1 | 2019 |
| ATIM-16. VALIDATION OF RESPONSE TO NEOADJUVANT ANTI-PD-1 IMMUNOTHERAPY IN RECURRENT GLIOBLASTOMA F Chow, A Mochizuki, A Lee, M Galvez, J Orpilla, R Everson, L Liau, ... Neuro-oncology 21 (Suppl 6), vi4, 2019 | 1 | 2019 |
| PROTEIN MICROARRAY ANALYSIS OF GLIOBLASTOMA PATIENT SERA BEFORE AND AFTER DENDRITIC CELL VACCINATION A Tucker, R Everson, J Orpilla, H Soto, F Yuan, L Liau, R Prins NEURO-ONCOLOGY 18, 25-25, 2016 | 1 | 2016 |
| P15. 04. A BIOLOGICAL CORRELATES OF LEAKAGE EFFECT METRICS COMPUTED FROM DYNAMIC SAGE-EPI MRI IN ENHANCING AND NON-ENHANCING HUMAN GLIOMAS F Sanvito, C Raymond, NS Cho, J Yao, A Hagiwara, J Orpilla, LL Liau, ... Neuro-Oncology 25 (Supplement_2), ii110-ii110, 2023 | | 2023 |
| MULTI-ECHO SPIN-AND-GRADIENT ECHO (SAGE) PERFUSION MRI TO EVALUATE BRAIN TUMOR MICROSTRUCTURE AND MICROVASCULATURE F Sanvito, C Raymond, NS Cho, A Hagiwara, J Orpilla, N Salamon, ... NEURO-ONCOLOGY 24, 174-174, 2022 | | 2022 |
| EXTH-87. DECITABINE POTENTIATES MENINGIOMA IMMUNOTHERAPY TARGETING NY-ESO-1 M Sun, J Orpilla, E Contreras, M Imbroane, J Treger, A Wang, MJ Ko, ... Neuro-Oncology 24 (Supplement_7), vii229-vii229, 2022 | | 2022 |
| Engineering T Cell Receptors to Target H3. 3G34 Mutant Glioblastoma AC Wang, G Owens, A Lee, MZ Sun, S Peeters, JC Kienzler, J Orpilla, ... Neurosurgery 67, 2020 | | 2020 |
| CTIM-18. DENDRITIC CELL VACCINATION IN CONJUNCTION WITH ADJUVANT TLR-3 AGONIST ADMINISTRATION ENHANCES PRO-INFLAMMATORY IMMUNE RESPONSES AND IS ASSOCIATED WITH EXTENDED … C Chavez, R Everson, J Orpilla, A Lee, S Khattab, J Antonios, A Salazar, ... Neuro-Oncology, ii36, 2020 | | 2020 |
| IMMU-20. SINGLE-CELL RNASEQ OF TUMOR INFILTRATING IMMUNE CELLS FROM NEOADJUVANT ANTI-PD1 TREATED GBM PATIENTS REVEALS GLOBAL TRANSCRIPTIONAL CHANGES AND IMMUNOSUPPRESSIVE … A Lee, A Mochizuki, F Chow, J Reynoso, J Orpilla, L Sun, C Chavez, ... Neuro-Oncology 22 (Supplement_2), ii108-ii109, 2020 | | 2020 |
