| Application of fundamental organometallic chemistry to the development of a gold‐catalyzed synthesis of sulfinate derivatives MW Johnson, SW Bagley, NP Mankad, RG Bergman, V Mascitti, FD Toste Angewandte Chemie International Edition 53 (17), 4404-4407, 2014 | 245 | 2014 |
| One-pot palladium-catalyzed synthesis of sulfonyl fluorides from aryl bromides AT Davies, JM Curto, SW Bagley, MC Willis Chemical Science 8 (2), 1233-1237, 2017 | 175 | 2017 |
| Decarboxylative cross-nucleophile coupling via ligand-to-metal charge transfer photoexcitation of Cu(ii) carboxylates QY Li, SN Gockel, GA Lutovsky, KS DeGlopper, NJ Baldwin, ... Nature chemistry 14 (1), 94-99, 2022 | 110 | 2022 |
| Decreasing the rate of metabolic ketone reduction in the discovery of a clinical acetyl-CoA carboxylase inhibitor for the treatment of diabetes DA Griffith, DW Kung, WP Esler, PA Amor, SW Bagley, C Beysen, ... Journal of medicinal chemistry 57 (24), 10512-10526, 2014 | 83 | 2014 |
| Six-membered ring fused imidazoles substituted with phenoxyphenylacetic acid derivatives SW Bagley, PK Chakravarty, A Chen, DS Dhanoa, KJ Fitch, WJ Greenlee, ... US Patent 5,334,598, 1994 | 82 | 1994 |
| Cyclic Alkenylsulfonyl Fluorides: Palladium‐Catalyzed Synthesis and Functionalization of Compact Multifunctional Reagents TSB Lou, SW Bagley, MC Willis Angewandte Chemie 131 (52), 19035-19039, 2019 | 81 | 2019 |
| A small-molecule oral agonist of the human glucagon-like peptide-1 receptor DA Griffith, DJ Edmonds, JP Fortin, AS Kalgutkar, JB Kuzmiski, PM Loria, ... Journal of Medicinal Chemistry 65 (12), 8208-8226, 2022 | 70 | 2022 |
| Discovery of 2-(6-(5-Chloro-2-methoxyphenyl)-4-oxo-2-thioxo-3,4-dihydropyrimidin-1(2H)-yl)acetamide (PF-06282999): A Highly Selective Mechanism-Based … RB Ruggeri, L Buckbinder, SW Bagley, PA Carpino, EL Conn, ... Journal of medicinal chemistry 58 (21), 8513-8528, 2015 | 54 | 2015 |
| Phenoxyphenylacetic acid derivatives SW Bagley, TP Broten, PK Chakravarty, DS Dhanoa, KJ Fitch, ... US Patent 5,668,176, 1997 | 48 | 1997 |
| Discovery of an in Vivo Tool to Establish Proof-of-Concept for MAP4K4-Based Antidiabetic Treatment M Ammirati, SW Bagley, SK Bhattacharya, L Buckbinder, AA Carlo, ... ACS medicinal chemistry letters 6 (11), 1128-1133, 2015 | 43 | 2015 |
| Spirolactam-based acetyl-CoA carboxylase inhibitors: toward improved metabolic stability of a chromanone lead structure DA Griffith, RL Dow, K Huard, DJ Edmonds, SW Bagley, J Polivkova, ... Journal of medicinal chemistry 56 (17), 7110-7119, 2013 | 42 | 2013 |
| Non-peptide angiotensin II receptor antagonists. 1. Design, synthesis, and biological activity of N-substituted indoles and dihydroindoles DS Dhanoa, SW Bagley, RSL Chang, VJ Lotti, TB Chen, SD Kivlighn, ... Journal of medicinal chemistry 36 (26), 4230-4238, 1993 | 42 | 1993 |
| Identification of novel series of pyrazole and indole-urea based DFG-out PYK2 inhibitors SK Bhattacharya, GE Aspnes, SW Bagley, M Boehm, AD Brosius, ... Bioorganic & medicinal chemistry letters 22 (24), 7523-7529, 2012 | 35 | 2012 |
| A critical role for peroxisomal proliferator-activated receptor-α nuclear receptors in the development of cardiomyocyte degeneration and necrosis I Pruimboom-Brees, M Haghpassand, L Royer, D Brees, C Aldinger, ... The American journal of pathology 169 (3), 750-760, 2006 | 34 | 2006 |
| Synthesis of spiropiperidine lactam acetyl-CoA carboxylase inhibitors K Huard, SW Bagley, E Menhaji-Klotz, C Préville, JA Southers Jr, ... The Journal of organic chemistry 77 (22), 10050-10057, 2012 | 31 | 2012 |
| N1-pyrazolospiroketone acetyl-CoA carboxylase inhibitors SW Bagley, DA Griffith, DWS Kung US Patent 8,288,405, 2012 | 29 | 2012 |
| (Dipropylphenoxy) phenylacetic acids: a new generation of nonpeptide angiotensin II receptor antagonists DS Dhanoa, SW Bagley, RSL Chang, VJ Lotti, TB Chen, SD Kivlighn, ... Journal of medicinal chemistry 36 (23), 3738-3742, 1993 | 29 | 1993 |
| Short-acting 5-(trifluoromethyl) pyrido [4, 3-d] pyrimidin-4 (3H)-one derivatives as orally-active calcium-sensing receptor antagonists MT Didiuk, DA Griffith, JW Benbow, KKC Liu, DP Walker, FC Bi, J Morris, ... Bioorganic & medicinal chemistry letters 19 (16), 4555-4559, 2009 | 28 | 2009 |
| Discovery Tactics To Mitigate Toxicity Risks Due to Reactive Metabolite Formation with 2-(2-Hydroxyaryl)-5-(trifluoromethyl)pyrido[4,3-d]pyrimidin-4(3H)-one … AS Kalgutkar, DA Griffith, T Ryder, H Sun, Z Miao, JN Bauman, MT Didiuk, ... Chemical research in toxicology 23 (6), 1115-1126, 2010 | 27 | 2010 |
| Biphenyl compounds useful or endothelin antagonists SW Bagley, TP Broten, PK Chakravarty, DS Dhanoa, KJ Fitch, ... US Patent 5,565,485, 1996 | 27 | 1996 |
