| Passage of erythropoietic agents across the blood–brain barrier: a comparison of human and murine erythropoietin and the analog darbepoetin alfa WA Banks, NL Jumbe, CL Farrell, ML Niehoff, AC Heatherington European journal of pharmacology 505 (1-3), 93-101, 2004 | 173 | 2004 |
| Pharmacokinetics and pharmacodynamics of darbepoetin alfa and epoetin in patients undergoing dialysis M Allon, K Kleinman, M Walczyk, C Kaupke, L Messer‐Mann, K Olson, ... Clinical Pharmacology & Therapeutics 72 (5), 546-555, 2002 | 98 | 2002 |
| Pharmacokinetics of novel erythropoiesis stimulating protein (NESP) in cancer patients: preliminary report AC Heatherington, J Schuller, AJ Mercer British journal of cancer 84 (1), 11-16, 2001 | 87 | 2001 |
| Pharmacokinetics of darbepoetin alfa in pediatric patients with chronic kidney disease G Lerner, AS Kale, BA Warady, K Jabs, TE Bunchman, A Heatherington, ... Pediatric Nephrology 17, 933-937, 2002 | 71 | 2002 |
| Lymphatic absorption is the primary contributor to the systemic availability of epoetin alfa following subcutaneous administration to sheep DN McLennan, CJH Porter, GA Edwards, SW Martin, AC Heatherington, ... Journal of Pharmacology and Experimental Therapeutics 313 (1), 345-351, 2005 | 61 | 2005 |
| Development and evaluation of a population pharmacokinetic-pharmacodynamic model of darbepoetin alfa in patients with nonmyeloid malignancies undergoing multicycle chemotherapy B Agoram, AC Heatherington, MR Gastonguay The AAPS journal 8, E552-E563, 2006 | 60 | 2006 |
| Quantitative systems pharmacology: a case for disease models CJ Musante, S Ramanujan, BJ Schmidt, OG Ghobrial, J Lu, ... Clinical Pharmacology & Therapeutics 101 (1), 24-27, 2017 | 54 | 2017 |
| A pharmacokinetic/pharmacodynamic comparison of SAAM II and PC/WinNonlin modeling software AC Heatherington, P Vicini, H Golde Journal of pharmaceutical sciences 87 (10), 1255-1263, 1998 | 46 | 1998 |
| Discovery of a selective small-molecule melanocortin-4 receptor agonist with efficacy in a pilot study of sexual dysfunction in humans MI Lansdell, D Hepworth, A Calabrese, AD Brown, J Blagg, DJ Burring, ... Journal of medicinal chemistry 53 (8), 3183-3197, 2010 | 44 | 2010 |
| The absorption of darbepoetin alfa occurs predominantly via the lymphatics following subcutaneous administration to sheep DN McLennan, CJH Porter, GA Edwards, AC Heatherington, SW Martin, ... Pharmaceutical research 23, 2060-2066, 2006 | 41 | 2006 |
| Kinetics of haematopoietic recovery after dose‐intensive chemo/radiotherapy in mice: optimized erythroid support with darbepoetin alpha C Hartley, S Elliott, CG Begley, P McElroy, W Sutherland, R Khaja, ... British journal of haematology 122 (4), 623-636, 2003 | 40 | 2003 |
| A Multiscale Model of Interleukin‐6–Mediated Immune Regulation in Crohn's Disease and Its Application in Drug Discovery and Development G Dwivedi, L Fitz, M Hegen, SW Martin, J Harrold, A Heatherington, C Li CPT: Pharmacometrics & Systems Pharmacology 3 (1), 1-9, 2014 | 37 | 2014 |
| Novel erythropoiesis stimulating protein (NESP) exhibits a prolonged serum half-life in oncology patients J Glaspy, AB Colowick, A Heatherington Proc Am Soc Clin Oncol 19, 54a, 2000 | 29 | 2000 |
| Clinical trial simulation of a 200-microg fixed dose of darbepoetin alfa in chemotherapy-induced anemia. N Jumbe, B Yao, R Rovetti, G Rossi, AC Heatherington Oncology (Williston Park, NY) 16 (10 Suppl 11), 37-44, 2002 | 28 | 2002 |
| The pharmacokinetics of novel erythropoiesis stimulating protein (NESP) following chronic intravenous administration is time-and dose-linear M Allon, K Kleinman, M Walczyk, C Kaupke, BJ Maroni, A Heatherington, ... J Am Soc Nephrol 11, A1308, 2000 | 26 | 2000 |
| Pharmacokinetic-pharmacodynamic modeling of stimulatory and sedative effects of alprazolam: timing performance deficits CE Lau, AC Heatherington Journal of Pharmacology and Experimental Therapeutics 283 (3), 1119-1129, 1997 | 26 | 1997 |
| Using a systems pharmacology model of the blood coagulation network to predict the effects of various therapies on biomarkers S Nayak, D Lee, S Patel‐Hett, DD Pittman, SW Martin, AC Heatherington, ... CPT: pharmacometrics & systems pharmacology 4 (7), 396-405, 2015 | 24 | 2015 |
| The pharmacokinetics of novel erythropoiesis stimulating protein (NESP) in pediatric patients with chronic renal failure (CRF) or end-stage renal disease GR Lerner, AS Kale, BA Warady, KL Jabs, TE Bunchman, BJ Maroni, ... J Am Soc Nephrol 11, A1479, 2000 | 24 | 2000 |
| Clinical dose–response for a broad set of biological products: a model-based meta-analysis J Wu, A Banerjee, B Jin, SM Menon, SW Martin, AC Heatherington Statistical Methods in Medical Research 27 (9), 2694-2721, 2018 | 21 | 2018 |
| Application of quantitative pharmacology approaches in bridging pharmacokinetics and pharmacodynamics of domagrozumab from adult healthy subjects to pediatric patients with … I Bhattacharya, Z Manukyan, P Chan, A Heatherington, L Harnisch The Journal of Clinical Pharmacology 58 (3), 314-326, 2018 | 21 | 2018 |
