CGG repeat-associated translation mediates neurodegeneration in fragile X tremor ataxia syndrome PK Todd, SY Oh, A Krans, F He, C Sellier, M Frazer, AJ Renoux, K Chen, ... Neuron 78 (3), 440-455, 2013 | 499 | 2013 |
Discovery of novel DENN proteins: implications for the evolution of eukaryotic intracellular membrane structures and human disease D Zhang, LM Iyer, F He, L Aravind Frontiers in Genetics 3, 283, 0 | 296 | |
Sequestration of DROSHA and DGCR8 by expanded CGG RNA repeats alters microRNA processing in fragile X-associated tremor/ataxia syndrome C Sellier, F Freyermuth, R Tabet, T Tran, F He, F Ruffenach, V Alunni, ... Cell reports 3 (3), 869-880, 2013 | 248 | 2013 |
Translation of expanded CGG repeats into FMRpolyG is pathogenic and may contribute to fragile X tremor ataxia syndrome C Sellier, RAM Buijsen, F He, S Natla, L Jung, P Tropel, A Gaucherot, ... Neuron 93 (2), 331-347, 2017 | 215 | 2017 |
RAN translation at CGG repeats induces ubiquitin proteasome system impairment in models of fragile X-associated tremor ataxia syndrome SY Oh, F He, A Krans, M Frazer, JP Taylor, HL Paulson, PK Todd Human molecular genetics 24 (15), 4317-4326, 2015 | 104 | 2015 |
C9 ORF 72 expansion in a family with bipolar disorder MH Meisler, AE Grant, JM Jones, GM Lenk, F He, PK Todd, M Kamali, ... Bipolar disorders 15 (3), 326-332, 2013 | 67 | 2013 |
TDP-43 suppresses CGG repeat-induced neurotoxicity through interactions with HnRNP A2/B1 F He, A Krans, BD Freibaum, JP Taylor, PK Todd Human molecular genetics 23 (19), 5036-5051, 2014 | 63 | 2014 |
DDX3X and specific initiation factors modulate FMR1 repeat‐associated non‐AUG‐initiated translation AE Linsalata, F He, AM Malik, MR Glineburg, KM Green, S Natla, ... EMBO reports 20 (9), e47498, 2019 | 62 | 2019 |
Caspase‐mediated Degradation of PPARγ Proteins in Adipocytes F He, JA Doucet, JM Stephens Obesity 16 (8), 1735-1741, 2008 | 54 | 2008 |
Epigenetics in nucleotide repeat expansion disorders F He, PK Todd Seminars in neurology 31 (05), 470-483, 2011 | 48 | 2011 |
Small Molecule Recognition and Tools to Study Modulation of r(CGG)exp in Fragile X-Associated Tremor Ataxia Syndrome WY Yang, F He, RL Strack, SY Oh, M Frazer, SR Jaffrey, PK Todd, ... ACS chemical biology 11 (9), 2456-2465, 2016 | 47 | 2016 |
Deletion of Drosophila Nopp140 induces subcellular ribosomopathies F He, A James, H Raje, H Ghaffari, P DiMario Chromosoma 124, 191-208, 2015 | 28 | 2015 |
Drosophila delta-1-pyrroline-5-carboxylate dehydrogenase (P5CDh) is required for proline breakdown and mitochondrial integrity—establishing a fly model for human type II … F He, PJ DiMario Mitochondrion 11 (3), 397-404, 2011 | 27 | 2011 |
Induction of SOCS-3 is insufficient to confer IRS-1 protein degradation in 3T3-L1 adipocytes F He, JM Stephens Biochemical and biophysical research communications 344 (1), 95-98, 2006 | 20 | 2006 |
The carboxyl termini of RAN translated GGGGCC nucleotide repeat expansions modulate toxicity in models of ALS/FTD F He, BN Flores, A Krans, M Frazer, S Natla, S Niraula, O Adefioye, ... Acta Neuropathologica Communications 8, 1-17, 2020 | 16 | 2020 |
Structure and function of Nopp140 and Treacle F He, P DiMario The nucleolus, 253-278, 2011 | 16 | 2011 |
Degradation of STAT5 proteins in 3T3-L1 adipocytes is induced by TNF-α and cycloheximide in a manner independent of STAT5A activation ZE Floyd, BM Segura, F He, JM Stephens American Journal of Physiology-Endocrinology and Metabolism 292 (2), E461-E468, 2007 | 12 | 2007 |
Large-scale screening of disease model through ENU mutagenesis in mice F He, Z Wang, J Zhao, J Bao, J Ding, H Ruan, Q Xie, Z Zhang, X Gao Chinese Science Bulletin 48 (24), 2665-2671, 2003 | 9 | 2003 |
Spinocerebellar ataxia 36: From mutations toward therapies S Lopez, F He Frontiers in Genetics 13, 837690, 2022 | 6 | 2022 |
Screening for novel hexanucleotide repeat expansions at ALS-and FTD-associated loci F He, JM Jones, C Figueroa-Romero, D Zhang, EL Feldman, SA Goutman, ... Neurology: Genetics 2 (3), e71, 2016 | 5 | 2016 |