| Physiologically based pharmacokinetic (PBPK) modeling and simulation approaches: a systematic review of published models, applications, and model verification JE Sager, J Yu, I Ragueneau-Majlessi, N Isoherranen Drug Metabolism and Disposition 43 (11), 1823-1837, 2015 | 444 | 2015 |
| Effect of CYP3A5 polymorphism on tacrolimus metabolic clearance in vitro Y Dai, MF Hebert, N Isoherranen, CL Davis, C Marsh, DD Shen, ... Drug metabolism and disposition 34 (5), 836-847, 2006 | 373 | 2006 |
| Design and optimization of dosage regimens: pharmacokinetic data KE Thummel, DD Shen, N Isoherranen, HE Smith Goodman & Gilman’s the pharmacological basis of therapeutics 11, 1787-1888, 2006 | 327 | 2006 |
| Role of itraconazole metabolites in CYP3A4 inhibition N Isoherranen, KL Kunze, KE Allen, WL Nelson, KE Thummel Drug Metabolism and Disposition 32 (10), 1121-1131, 2004 | 309 | 2004 |
| Cannabis use during pregnancy: pharmacokinetics and effects on child development KS Grant, R Petroff, N Isoherranen, N Stella, TM Burbacher Pharmacology & therapeutics 182, 133-151, 2018 | 261 | 2018 |
| Evidence of significant contribution from CYP3A5 to hepatic drug metabolism W Huang, YS Lin, DJ McConn, JC Calamia, RA Totah, N Isoherranen, ... Drug metabolism and disposition 32 (12), 1434-1445, 2004 | 247 | 2004 |
| The role of CYP26 enzymes in retinoic acid clearance JE Thatcher, N Isoherranen Expert opinion on drug metabolism & toxicology 5 (8), 875-886, 2009 | 226 | 2009 |
| Drug metabolism and transport during pregnancy: how does drug disposition change during pregnancy and what are the mechanisms that cause such changes? N Isoherranen, KE Thummel Drug Metabolism and Disposition 41 (2), 256-262, 2013 | 218 | 2013 |
| Commensals suppress intestinal epithelial cell retinoic acid synthesis to regulate interleukin-22 activity and prevent microbial dysbiosis M Grizotte-Lake, G Zhong, K Duncan, J Kirkwood, N Iyer, I Smolenski, ... Immunity 49 (6), 1103-1115. e6, 2018 | 161 | 2018 |
| Contribution of Itraconazole Metabolites to Inhibition of CYP3A4 In Vivo IE Templeton, KE Thummel, ED Kharasch, KL Kunze, C Hoffer, ... Clinical Pharmacology & Therapeutics 83 (1), 77-85, 2008 | 152 | 2008 |
| Suppression of spermatogenesis by bisdichloroacetyldiamines is mediated by inhibition of testicular retinoic acid biosynthesis JK Amory, CH Muller, JA Shimshoni, N Isoherranen, J Paik, JS Moreb, ... Journal of andrology 32 (1), 111-119, 2011 | 137 | 2011 |
| Chromatographic methods for analysis of aminoglycoside antibiotics N Isoherranen, S Soback Journal of AOAC International 82 (5), 1017-1045, 1999 | 135 | 1999 |
| A sensitive and specific method for measurement of multiple retinoids in human serum with UHPLC-MS/MS SLM Arnold, JK Amory, TJ Walsh, N Isoherranen Journal of lipid research 53 (3), 587-598, 2012 | 125 | 2012 |
| Processive pulses of retinoic acid propel asynchronous and continuous murine sperm production CA Hogarth, S Arnold, T Kent, D Mitchell, N Isoherranen, MD Griswold Biology of reproduction 92 (2), 37, 1-11, 2015 | 115 | 2015 |
| New CNS-active drugs which are second-generation valproic acid: can they lead to the development of a magic bullet? N Isoherranen, B Yagen, M Bialer Current opinion in neurology 16 (2), 203-211, 2003 | 115 | 2003 |
| Comparison of the function and expression of CYP26A1 and CYP26B1, the two retinoic acid hydroxylases AR Topletz, JE Thatcher, A Zelter, JD Lutz, S Tay, WL Nelson, ... Biochemical pharmacology 83 (1), 149-163, 2012 | 114 | 2012 |
| Influence of CYP3A5 Genotype on the Pharmacokinetics and Pharmacodynamics of the Cytochrome P4503A Probes Alfentanil and Midazolam ED Kharasch, A Walker, N Isoherranen, C Hoffer, P Sheffels, K Thummel, ... Clinical Pharmacology & Therapeutics 82 (4), 410-426, 2007 | 114 | 2007 |
| Inhibition of CYP2C19 and CYP3A4 by omeprazole metabolites and their contribution to drug-drug interactions Y Shirasaka, JE Sager, JD Lutz, C Davis, N Isoherranen Drug Metabolism and Disposition 41 (7), 1414-1424, 2013 | 111 | 2013 |
| A Specific Inhibitor of PfCDPK4 Blocks Malaria Transmission: Chemical-genetic Validation KK Ojo, RT Eastman, RSR Vidadala, Z Zhang, KL Rivas, R Choi, JD Lutz, ... The Journal of infectious diseases 209 (2), 275-284, 2014 | 101 | 2014 |
| Expression and functional characterization of cytochrome P450 26A1, a retinoic acid hydroxylase JD Lutz, V Dixit, CK Yeung, LJ Dickmann, A Zelter, JE Thatcher, ... Biochemical pharmacology 77 (2), 258-268, 2009 | 98 | 2009 |
