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Philip J.M. Brouwer
Philip J.M. Brouwer
Verified email at scripps.edu
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Cited by
Year
Potent neutralizing antibodies from COVID-19 patients define multiple targets of vulnerability
PJM Brouwer, TG Caniels, K van der Straten, JL Snitselaar, Y Aldon, ...
Science 369 (6504), 643-650, 2020
11622020
Afucosylated IgG characterizes enveloped viral responses and correlates with COVID-19 severity
MD Larsen, EL de Graaf, ME Sonneveld, HR Plomp, J Nouta, W Hoepel, ...
Science 371 (6532), eabc8378, 2021
3092021
Cross-neutralization of a SARS-CoV-2 antibody to a functionally conserved site is mediated by avidity
H Liu, NC Wu, M Yuan, S Bangaru, JL Torres, TG Caniels, ...
Immunity 53 (6), 1272-1280. e5, 2020
2052020
High titers and low fucosylation of early human anti–SARS-CoV-2 IgG promote inflammation by alveolar macrophages
W Hoepel, HJ Chen, CE Geyer, S Allahverdiyeva, XD Manz, SW de Taeye, ...
Science translational medicine 13 (596), eabf8654, 2021
1722021
Two-component spike nanoparticle vaccine protects macaques from SARS-CoV-2 infection
PJM Brouwer, M Brinkkemper, P Maisonnasse, N Dereuddre-Bosquet, ...
Cell 184, 1-13, 2021
1552021
An alternative binding mode of IGHV3-53 antibodies to the SARS-CoV-2 receptor binding domain
NC Wu, M Yuan, H Liu, CCD Lee, X Zhu, S Bangaru, JL Torres, ...
Cell reports 33 (3), 2020
1532020
Enhancing and shaping the immunogenicity of native-like HIV-1 envelope trimers with a two-component protein nanoparticle
PJM Brouwer, A Antanasijevic, Z Berndsen, A Yasmeen, B Fiala, TPL Bijl, ...
Nature Communications 10 (1), 4272, 2019
1522019
Tailored Design of Protein Nanoparticle Scaffolds for Multivalent Presentation of Viral Glycoprotein Antigens
G Ueda, A Antanasijevic, JA Fallas, W Sheffler, J Copps, D Ellis, ...
Elife, 2020
1302020
Antibody responses to SARS-CoV-2 mRNA vaccines are detectable in saliva
TJ Ketas, D Chaturbhuj, VMC Portillo, E Francomano, E Golden, ...
Pathogens and Immunity 6 (1), 116, 2021
1292021
Structure and immunogenicity of a stabilized HIV-1 envelope trimer based on a group-M consensus sequence
K Sliepen, BW Han, I Bontjer, P Mooij, F Garces, AJ Behrens, ...
Nature communications 10 (1), 2355, 2019
1272019
Comparative assessment of multiple COVID-19 serological technologies supports continued evaluation of point-of-care lateral flow assays in hospital and community healthcare …
S Pickering, G Betancor, RP Galao, B Merrick, AW Signell, HD Wilson, ...
Plos Pathogens, 2020
1212020
Cross-reactive antibodies after SARS-CoV-2 infection and vaccination
M Grobben, K van der Straten, PJM Brouwer, M Brinkkemper, ...
Elife 10, e70330, 2021
752021
Site-specific steric control of SARS-CoV-2 spike glycosylation
JD Allen, H Chawla, F Samsudin, L Zuzic, AT Shivgan, Y Watanabe, ...
Biochemistry 60 (27), 2153-2169, 2021
622021
Human milk from previously COVID-19-infected mothers: the effect of pasteurization on specific antibodies and neutralization capacity
BJ van Keulen, M Romijn, A Bondt, KA Dingess, E Kontopodi, ...
Nutrients 13 (5), 1645, 2021
612021
Anti-SARS-CoV-2 IgG from severely ill COVID-19 patients promotes macrophage hyper-inflammatory responses
W Hoepel, HJ Chen, S Allahverdiyeva, X Manz, J Aman, ...
BioRxiv, 2020.07. 13.190140, 2020
572020
Structural and functional evaluation of de novo-designed, two-component nanoparticle carriers for HIV Env trimer immunogens
A Antanasijevic, G Ueda, J Copps, PJM Brouwer, D Huang, JD Allen, ...
Plos Pathogens, 2020
552020
Infection and transmission of SARS‐CoV‐2 depend on heparan sulfate proteoglycans
M Bermejo‐Jambrina, J Eder, TM Kaptein, JL van Hamme, LC Helgers, ...
The EMBO Journal 40 (20), e106765, 2021
492021
COVA1-18 neutralizing antibody protects against SARS-CoV-2 in three preclinical models
P Maisonnasse, Y Aldon, A Marc, R Marlin, N Dereuddre-Bosquet, ...
Nature communications 12 (1), 6097, 2021
432021
Immunofocusing and enhancing autologous Tier-2 HIV-1 neutralization by displaying Env trimers on two-component protein nanoparticles
PJM Brouwer, A Antanasijevic, M de Gast, JD Allen, TPL Bijl, A Yasmeen, ...
npj Vaccines 6 (24), 2021
342021
A public antibody class recognizes an S2 epitope exposed on open conformations of SARS-CoV-2 spike
M Claireaux, TG Caniels, M de Gast, J Han, D Guerra, G Kerster, ...
Nature communications 13 (1), 4539, 2022
322022
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