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Tiffany Wu
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Reducing endogenous tau ameliorates amyloid ß-induced deficits in an Alzheimer's disease mouse model
ED Roberson, K Scearce-Levie, JJ Palop, F Yan, IH Cheng, T Wu, ...
Science 316 (5825), 750-754, 2007
23132007
Amyloid-β/Fyn–induced synaptic, network, and cognitive impairments depend on tau levels in multiple mouse models of Alzheimer's disease
ED Roberson, B Halabisky, JW Yoo, J Yao, J Chin, F Yan, T Wu, P Hamto, ...
Journal of Neuroscience 31 (2), 700-711, 2011
7472011
Kynurenine 3-monooxygenase inhibition in blood ameliorates neurodegeneration
D Zwilling, SY Huang, KV Sathyasaikumar, FM Notarangelo, P Guidetti, ...
Cell 145 (6), 863-874, 2011
5202011
Changes in the synaptic proteome in tauopathy and rescue of tau-induced synapse loss by C1q antibodies
B Dejanovic, MA Huntley, A De Mazière, WJ Meilandt, T Wu, K Srinivasan, ...
Neuron 100 (6), 1322-1336. e7, 2018
3702018
Complement C3 is activated in human AD brain and is required for neurodegeneration in mouse models of amyloidosis and tauopathy
T Wu, B Dejanovic, VD Gandham, A Gogineni, R Edmonds, S Schauer, ...
Cell reports 28 (8), 2111-2123. e6, 2019
3212019
Neprilysin overexpression inhibits plaque formation but fails to reduce pathogenic Aβ oligomers and associated cognitive deficits in human amyloid precursor protein transgenic mice
WJ Meilandt, M Cisse, K Ho, T Wu, LA Esposito, K Scearce-Levie, ...
Journal of Neuroscience 29 (7), 1977-1986, 2009
1862009
Trem2 deletion reduces late-stage amyloid plaque accumulation, elevates the Aβ42: Aβ40 ratio, and exacerbates axonal dystrophy and dendritic spine loss in the PS2APP Alzheimer …
WJ Meilandt, H Ngu, A Gogineni, G Lalehzadeh, SH Lee, K Srinivasan, ...
Journal of Neuroscience 40 (9), 1956-1974, 2020
1312020
Reversal-specific learning impairments after a binge regimen of methamphetamine in rats: possible involvement of striatal dopamine
A Izquierdo, AM Belcher, L Scott, VA Cazares, J Chen, SJ O'dell, ...
Neuropsychopharmacology 35 (2), 505-514, 2010
1192010
Enkephalin elevations contribute to neuronal and behavioral impairments in a transgenic mouse model of Alzheimer's disease
WJ Meilandt, GQ Yu, J Chin, ED Roberson, JJ Palop, T Wu, ...
Journal of Neuroscience 28 (19), 5007-5017, 2008
1072008
Complement C1q-dependent excitatory and inhibitory synapse elimination by astrocytes and microglia in Alzheimer’s disease mouse models
B Dejanovic, T Wu, MC Tsai, D Graykowski, VD Gandham, CM Rose, ...
Nature aging 2 (9), 837-850, 2022
782022
Cognitive deficits, changes in synaptic function, and brain pathology in a mouse model of normal aging
M Weber, T Wu, JE Hanson, NM Alam, H Solanoy, H Ngu, BE Lauffer, ...
ENeuro 2 (5), 2015
682015
GluN2B antagonism affects interneurons and leads to immediate and persistent changes in synaptic plasticity, oscillations, and behavior
JE Hanson, M Weber, WJ Meilandt, T Wu, T Luu, L Deng, M Shamloo, ...
Neuropsychopharmacology 38 (7), 1221-1233, 2013
562013
A death receptor 6-amyloid precursor protein pathway regulates synapse density in the mature CNS but does not contribute to Alzheimer's disease-related pathophysiology in …
DY Kallop, WJ Meilandt, A Gogineni, C Easley-Neal, T Wu, AM Jubb, ...
Journal of Neuroscience 34 (19), 6425-6437, 2014
472014
BACE1 across species: a comparison of the in vivo consequences of BACE1 deletion in mice and rats
M Weber, T Wu, WJ Meilandt, SL Dominguez, HO Solanoy, JA Maloney, ...
Scientific Reports 7 (1), 44249, 2017
182017
Motor cortex stimulation: mild transient benefit in a primate model of Parkinson disease
AK Wu, KW McCairn, G Zada, T Wu, RS Turner
Journal of neurosurgery 106 (4), 695-700, 2007
152007
TPL2 kinase activity regulates microglial inflammatory responses and promotes neurodegeneration in tauopathy mice
Y Wang, T Wu, MC Tsai, MG Rezzonico, AM Abdel-Haleem, L Xie, ...
Elife 12, e83451, 2023
22023
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