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SILVIA ORTEGA GUTIERREZ
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Year
CB1 cannabinoid receptors and on-demand defense against excitotoxicity
G Marsicano, S Goodenough, K Monory, H Hermann, M Eder, A Cannich, ...
Science 302 (5642), 84-88, 2003
13912003
Mitochondrial CB1 receptors regulate neuronal energy metabolism
G Bénard, F Massa, N Puente, J Lourenço, L Bellocchio, E Soria-Gómez, ...
Nature neuroscience 15 (4), 558-564, 2012
6072012
The anxiolytic effect of cannabidiol on chronically stressed mice depends on hippocampal neurogenesis: involvement of the endocannabinoid system
AC Campos, Z Ortega, J Palazuelos, MV Fogaça, DC Aguiar, ...
International Journal of Neuropsychopharmacology 16 (6), 1407-1419, 2013
3032013
Endocannabinoids drive the acquisition of an alternative phenotype in microglia
M Mecha, A Feliú, FJ Carrillo-Salinas, A Rueda-Zubiaurre, ...
Brain, behavior, and immunity 49, 233-245, 2015
2052015
A double-blind, randomized, cross-over, placebo-controlled, pilot trial with Sativex in Huntington’s disease
JL López-Sendón Moreno, J García Caldentey, P Trigo Cubillo, ...
Journal of neurology 263, 1390-1400, 2016
1392016
Activation of the endocannabinoid system as a therapeutic approach in a murine model of multiple sclerosis
S Ortega‐Gutiérrez, E Molina‐Holgado, Á Arévalo‐Martín, F Correa, ...
The FASEB journal 19 (10), 1338-1340, 2005
1342005
Novel inhibitors of fatty acid synthase with anticancer activity
T Puig, C Turrado, B Benhamú, H Aguilar, J Relat, S Ortega-Gutiérrez, ...
Clinical Cancer Research 15 (24), 7608-7615, 2009
1302009
A novel inhibitor of fatty acid synthase shows activity against HER2+ breast cancer xenografts and is active in anti-HER2 drug-resistant cell lines
T Puig, H Aguilar, S Cufí, G Oliveras, C Turrado, S Ortega-Gutiérrez, ...
Breast Cancer Research 13, 1-13, 2011
1222011
Role of Cannabinoid Receptor CB2 in HER2 Pro-oncogenic Signaling in Breast Cancer
E Pérez-Gómez, C Andradas, S Blasco-Benito, MM Caffarel, ...
Journal of the National Cancer Institute 107 (6), djv077, 2015
1182015
Effect of anandamide uptake inhibition in the production of nitric oxide and in the release of cytokines in astrocyte cultures
S Ortega‐Gutiérrez, E Molina‐Holgado, C Guaza
Glia 52 (2), 163-168, 2005
1132005
A reversible and selective inhibitor of monoacylglycerol lipase ameliorates multiple sclerosis
G Hernández‐Torres, M Cipriano, E Hedén, E Björklund, Á Canales, ...
Angewandte Chemie 126 (50), 13985-13990, 2014
1122014
Comparison of anandamide transport in FAAH wild-type and knockout neurons: evidence for contributions by both FAAH and the CB1 receptor to anandamide uptake
S Ortega-Gutiérrez, EG Hawkins, A Viso, ML López-Rodríguez, BF Cravatt
Biochemistry 43 (25), 8184-8190, 2004
1072004
Design, synthesis, and biological evaluation of new inhibitors of the endocannabinoid uptake: comparison with effects on fatty acid amidohydrolase
ML López-Rodríguez, A Viso, S Ortega-Gutiérrez, CJ Fowler, G Tiger, ...
Journal of medicinal chemistry 46 (8), 1512-1522, 2003
1052003
The constitutive production of the endocannabinoid 2‐arachidonoylglycerol participates in oligodendrocyte differentiation
O Gomez, A Arevalo‐Martin, D Garcia‐Ovejero, S Ortega‐Gutierrez, ...
Glia 58 (16), 1913-1927, 2010
1042010
Monoacylglycerol lipase (MAGL) as a promising therapeutic target
A Gil-Ordóñez, M Martín-Fontecha, S Ortega-Gutiérrez, ...
Biochemical pharmacology 157, 18-32, 2018
972018
Effect of repeated systemic administration of selective inhibitors of endocannabinoid inactivation on rat brain endocannabinoid levels
E De Lago, S Petrosino, M Valenti, E Morera, S Ortega-Gutierrez, ...
Biochemical pharmacology 70 (3), 446-452, 2005
922005
Design, synthesis and biological evaluation of novel arachidonic acid derivatives as highly potent and selective endocannabinoid transporter inhibitors
ML López-Rodríguez, A Viso, S Ortega-Gutiérrez, I Lastres-Becker, ...
Journal of medicinal chemistry 44 (26), 4505-4508, 2001
902001
UCM707, an inhibitor of the anandamide uptake, behaves as a symptom control agent in models of Huntington's disease and multiple sclerosis, but fails to delay/arrest the …
E De Lago, J Fernández-Ruiz, S Ortega-Gutiérrez, A Cabranes, G Pryce, ...
European neuropsychopharmacology 16 (1), 7-18, 2006
862006
UCM707, a potent and selective inhibitor of endocannabinoid uptake, potentiates hypokinetic and antinociceptive effects of anandamide
E de Lago, J Fernández-Ruiz, S Ortega-Gutiérrez, A Viso, ...
European journal of pharmacology 449 (1-2), 99-103, 2002
812002
New synthetic inhibitors of fatty acid synthase with anticancer activity
C Turrado, T Puig, J García-Cárceles, M Artola, B Benhamú, ...
Journal of medicinal chemistry 55 (11), 5013-5023, 2012
782012
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