Vassilios Myrianthopoulos
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Structural basis for the synthesis of indirubins as potent and selective inhibitors of glycogen synthase kinase-3 and cyclin-dependent kinases
P Polychronopoulos, P Magiatis, AL Skaltsounis, V Myrianthopoulos, ...
Journal of medicinal chemistry 47 (4), 935-946, 2004
Roscovitine-derived, dual-specificity inhibitors of cyclin-dependent kinases and casein kinases 1
N Oumata, K Bettayeb, Y Ferandin, L Demange, A Lopez-Giral, ...
Journal of medicinal chemistry 51 (17), 5229-5242, 2008
Soluble 3′, 6-substituted indirubins with enhanced selectivity toward glycogen synthase kinase-3 alter circadian period
K Vougogiannopoulou, Y Ferandin, K Bettayeb, V Myrianthopoulos, ...
Journal of medicinal chemistry 51 (20), 6421-6431, 2008
Senescence and senotherapeutics: a new field in cancer therapy
V Myrianthopoulos, K Evangelou, PVS Vasileiou, T Cooks, ...
Pharmacology & Therapeutics 193, 31-49, 2019
An integrated computational approach to the phenomenon of potent and selective inhibition of aurora kinases B and C by a series of 7-substituted indirubins
V Myrianthopoulos, P Magiatis, Y Ferandin, AL Skaltsounis, L Meijer, ...
Journal of medicinal chemistry 50 (17), 4027-4037, 2007
Novel inverse binding mode of indirubin derivatives yields improved selectivity for DYRK kinases
V Myrianthopoulos, M Kritsanida, N Gaboriaud-Kolar, P Magiatis, ...
ACS medicinal chemistry letters 4 (1), 22-26, 2013
6-Br-5methylindirubin-3′ oxime (5-Me-6-BIO) targeting the leishmanial glycogen synthase kinase-3 (GSK-3) short form affects cell-cycle progression and induces apoptosis-like …
E Xingi, D Smirlis, V Myrianthopoulos, P Magiatis, KM Grant, L Meijer, ...
International journal for parasitology 39 (12), 1289-1303, 2009
Identification of the substrate recognition and transport pathway in a eukaryotic member of the nucleobase-ascorbate transporter (NAT) family
V Kosti, G Lambrinidis, V Myrianthopoulos, G Diallinas, E Mikros
PLoS One 7 (7), e41939, 2012
Screening of a composite library of clinically used drugs and well-characterized pharmacological compounds for cystathionine β-synthase inhibition identifies benserazide as a …
N Druzhyna, B Szczesny, G Olah, K Módis, A Asimakopoulou, A Pavlidou, ...
Pharmacological research 113, 18-37, 2016
Modeling, substrate docking, and mutational analysis identify residues essential for the function and specificity of a eukaryotic purine-cytosine NCS1 transporter
E Krypotou, V Kosti, S Amillis, V Myrianthopoulos, E Mikros, G Diallinas
Journal of Biological Chemistry 287 (44), 36792-36803, 2012
Machine learning and data mining frameworks for predicting drug response in cancer: An overview and a novel in silico screening process based on association rule mining
K Vougas, T Sakellaropoulos, A Kotsinas, GRP Foukas, A Ntargaras, ...
Pharmacology & therapeutics 203, 107395, 2019
Two new peltogynoids from Acacia nilotica Delile with kinase inhibitory activity
A Ahmadu, A Abdulkarim, R Grougnet, V Myrianthopoulos, F Tillequin, ...
Planta medica 76 (05), 458-460, 2010
Exploring and exploiting the systemic effects of deregulated replication licensing
TG Petrakis, ES Komseli, M Papaioannou, K Vougas, A Polyzos, ...
Seminars in cancer biology 37, 3-15, 2016
An inhibitor-driven study for enhancing the selectivity of indirubin derivatives towards leishmanial Glycogen Synthase Kinase-3 over leishmanial cdc2-related protein kinase 3
A Efstathiou, N Gaboriaud-Kolar, D Smirlis, V Myrianthopoulos, ...
Parasites & vectors 7 (1), 1-12, 2014
Discovery and optimization of a selective ligand for the switch/sucrose nonfermenting-related bromodomains of polybromo protein-1 by the use of virtual screening and hydration …
V Myrianthopoulos, N Gaboriaud-Kolar, C Tallant, ML Hall, S Grigoriou, ...
Journal of medicinal chemistry 59 (19), 8787-8803, 2016
Tandem virtual screening targeting the SRA domain of UHRF1 identifies a novel chemical tool modulating DNA methylation
V Myrianthopoulos, PF Cartron, Z Liutkevičiūtė, S Klimašauskas, ...
European journal of medicinal chemistry 114, 390-396, 2016
A substrate translocation trajectory in a cytoplasm‐facing topological model of the monocarboxylate/H+ symporter Jen1p
I Soares‐Silva, J Sá‐Pessoa, V Myrianthopoulos, E Mikros, M Casal, ...
Molecular microbiology 81 (3), 805-817, 2011
Novel indole–flutimide heterocycles with activity against influenza PA endonuclease and hepatitis C virus
G Zoidis, E Giannakopoulou, A Stevaert, E Frakolaki, V Myrianthopoulos, ...
MedChemComm 7 (3), 447-456, 2016
The emerging field of senotherapeutic drugs
V Myrianthopoulos
Future medicinal chemistry 10 (20), 2369-2372, 2018
Selective cytotoxicity of the herbal substance acteoside against tumor cells and its mechanistic insights
C Cheimonidi, P Samara, P Polychronopoulos, EN Tsakiri, T Nikou, ...
Redox biology 16, 169-178, 2018
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