| Factor XII inhibition reduces thrombus formation in a primate thrombosis model A Matafonov, PY Leung, AE Gailani, SL Grach, C Puy, Q Cheng, M Sun, ... Blood 123 (11), 1739-1746, 2014 | 228 | 2014 |
| Binding of factor VIIa to the endothelial cell protein C receptor reduces its coagulant activity J LÓPEZ‐SAGASETA, R Montes, C Puy, N Díez, K Fukudome, J Hermida Journal of Thrombosis and Haemostasis 5 (9), 1817-1824, 2007 | 118 | 2007 |
| Factor XII promotes blood coagulation independent of factor XI in the presence of long‐chain polyphosphates C Puy, EI Tucker, ZC Wong, D Gailani, SA Smith, SH Choi, JH Morrissey, ... Journal of Thrombosis and Haemostasis 11 (7), 1341-1352, 2013 | 113 | 2013 |
| Activated protein C inhibits neutrophil extracellular trap formation in vitro and activation in vivo LD Healy, C Puy, JA Fernández, A Mitrugno, RS Keshari, NA Taku, ... Journal of Biological Chemistry, jbc. M116. 768309, 2017 | 111 | 2017 |
| Contact Activation Inhibitor and Factor XI Antibody, AB023, Produces Safe, Dose-Dependent Anticoagulation in a Phase 1 First-In-Human Trial CU Lorentz, NG Verbout, M Wallisch, MW Hagen, JJ Shatzel, SR Olson, ... Arteriosclerosis, thrombosis, and vascular biology, ATVBAHA. 118.312328, 2019 | 78 | 2019 |
| The hemostatic role of factor XI C Puy, RA Rigg, OJT McCarty Thrombosis research 141, S8-S11, 2016 | 77 | 2016 |
| Activated factor XI increases the procoagulant activity of the extrinsic pathway by inactivating tissue factor pathway inhibitor. C Puy, EI Tucker, A Matafonov, Q Cheng, KD Zientek, D Gailani, A Gruber, ... Blood, 2015 | 70 | 2015 |
| The Safety and Efficacy of Novel Agents Targeting Factors XI and XII in Early Phase Human Trials EP DeLoughery, SR Olson, C Puy, OJT McCarty, JJ Shatzel Seminars in Thrombosis and Hemostasis, 2019 | 55 | 2019 |
| Inhibition of contact-mediated activation of factor XI protects baboons against S aureus–induced organ damage and death R Silasi, RS Keshari, C Lupu, WJ Van Rensburg, H Chaaban, G Regmi, ... Blood advances 3 (4), 658-669, 2019 | 55 | 2019 |
| Nucleic acids as cofactors for factor XI and prekallikrein activation: Different roles for high-molecular-weight kininogen I Ivanov, M Sun, SK Dickeson, C Puy, OJT McCarty, A Gruber, ... Thrombosis and Haemostasis, 2017 | 44 | 2017 |
| Blocking endothelial protein C receptor (EPCR) accelerates thrombus development in vivo MN Centelles, C Puy, J Lopez-Sagaseta, K Fukudome, R Montes, ... Schattauer, 2010 | 37 | 2010 |
| Is EPCR a multi-ligand receptor? Pros and cons R Montes, C Puy, E Molina, J Hermida Thrombosis and haemostasis 107 (5), 815, 2012 | 36 | 2012 |
| Factor XII Activation Promotes Platelet Consumption in the Presence of Bacterial-Type Long-Chain Polyphosphate In Vitro and In Vivo J Zilberman-Rudenko, SE Reitsma, C Puy, RA Rigg, SA Smith, EI Tucker, ... Arteriosclerosis, Thrombosis, and Vascular Biology 38 (8), 1748-1760, 2018 | 34 | 2018 |
| Platelet-Derived Short-Chain Polyphosphates Enhance the Inactivation of Tissue Factor Pathway Inhibitor by Activated Coagulation Factor XI C Puy, EI Tucker, IS Ivanov, D Gailani, SA Smith, JH Morrissey, A Gruber, ... PloS one 11 (10), e0165172, 2016 | 34 | 2016 |
| Colocalization of neutrophils, extracellular DNA and coagulation factors during NETosis: Development and utility of an immunofluorescence-based microscopy platform LD Healy, C Puy, A Itakura, T Chu, DK Robinson, A Bylund, KG Phillips, ... Journal of Immunological Methods, 2016 | 32 | 2016 |
| Antibody inhibition of contact factor XII reduces platelet deposition in a model of extracorporeal membrane oxygenator perfusion in nonhuman primates M Wallisch, CU Lorentz, HHS Lakshmanan, J Johnson, MR Carris, C Puy, ... Research and Practice in Thrombosis and Haemostasis 4 (2), 205-216, 2020 | 30 | 2020 |
| Cross-Talk between the Complement Pathway and the Contact Activation System of Coagulation: Activated Factor XI Neutralizes Complement Factor H C Puy, J Pang, SE Reitsma, CU Lorentz, EI Tucker, D Gailani, A Gruber, ... The Journal of Immunology 206 (8), 1784-1792, 2021 | 29 | 2021 |
| sPLA2-V inhibits EPCR anticoagulant and antiapoptotic properties by accommodating lysophosphatidylcholine or PAF in the hydrophobic groove J López-Sagaseta, C Puy, I Tamayo, M Allende, J Cerveró, SE Velasco, ... Blood 119 (12), 2914-2921, 2012 | 29 | 2012 |
| Pharmacological targeting of coagulation factor XI mitigates the development of experimental atherosclerosis in low‐density lipoprotein receptor‐deficient mice ATP Ngo, KR Jordan, PA Mueller, MW Hagen, SE Reitsma, C Puy, ... Journal of Thrombosis and Haemostasis, 0 | 28 | |
| Endothelial PAI-1 (Plasminogen Activator Inhibitor-1) Blocks the Intrinsic Pathway of Coagulation, Inducing the Clearance and Degradation of FXIa (Activated Coagulation Factor XI) C Puy, ATP Ngo, J Pang, RS Keshari, MW Hagen, MT Hinds, D Gailani, ... Arteriosclerosis, Thrombosis, and Vascular Biology, ATVBAHA. 119.312619, 2018 | 26 | 2018 |
