| Succinate links TCA cycle dysfunction to oncogenesis by inhibiting HIF-α prolyl hydroxylase MA Selak, SM Armour, ED MacKenzie, H Boulahbel, DG Watson, ... Cancer cell 7 (1), 77-85, 2005 | 2304 | 2005 |
| SIRT1 deacetylase protects against neurodegeneration in models for Alzheimer's disease and amyotrophic lateral sclerosis D Kim, MD Nguyen, MM Dobbin, A Fischer, F Sananbenesi, JT Rodgers, ... The EMBO journal 26 (13), 3169-3179, 2007 | 1256 | 2007 |
| Mitochondrial membrane potential regulates matrix configuration and cytochrome c release during apoptosis E Gottlieb, SM Armour, MH Harris, CB Thompson Cell Death & Differentiation 10 (6), 709-717, 2003 | 794 | 2003 |
| Evidence for a common mechanism of SIRT1 regulation by allosteric activators BP Hubbard, AP Gomes, H Dai, J Li, AW Case, T Considine, TV Riera, ... Science 339 (6124), 1216-1219, 2013 | 657 | 2013 |
| Discrete functions of nuclear receptor Rev-erbα couple metabolism to the clock Y Zhang, B Fang, MJ Emmett, M Damle, Z Sun, D Feng, SM Armour, ... Science 348 (6242), 1488-1492, 2015 | 304 | 2015 |
| Circadian enhancers coordinate multiple phases of rhythmic gene transcription in vivo B Fang, LJ Everett, J Jager, E Briggs, SM Armour, D Feng, A Roy, ... Cell 159 (5), 1140-1152, 2014 | 219 | 2014 |
| IgG-cleaving endopeptidase enables in vivo gene therapy in the presence of anti-AAV neutralizing antibodies C Leborgne, E Barbon, JM Alexander, H Hanby, S Delignat, DM Cohen, ... Nature medicine 26 (7), 1096-1101, 2020 | 218 | 2020 |
| Inhibition of mammalian S6 kinase by resveratrol suppresses autophagy SM Armour, JA Baur, SN Hsieh, A Land-Bracha, SM Thomas, DA Sinclair Aging (Albany NY) 1 (6), 515, 2009 | 180 | 2009 |
| Sir-two-homolog 2 (Sirt2) modulates peripheral myelination through polarity protein Par-3/atypical protein kinase C (aPKC) signaling B Beirowski, J Gustin, SM Armour, H Yamamoto, A Viader, BJ North, ... Proceedings of the National Academy of Sciences 108 (43), E952-E961, 2011 | 169 | 2011 |
| Negative regulation of STAT3 protein-mediated cellular respiration by SIRT1 protein M Bernier, RK Paul, A Martin-Montalvo, M Scheibye-Knudsen, S Song, ... Journal of Biological Chemistry 286 (22), 19270-19279, 2011 | 151 | 2011 |
| Mitochondrial respiratory control is lost during growth factor deprivation E Gottlieb, SM Armour, CB Thompson Proceedings of the National Academy of Sciences 99 (20), 12801-12806, 2002 | 99 | 2002 |
| A high-confidence interaction map identifies SIRT1 as a mediator of acetylation of USP22 and the SAGA coactivator complex SM Armour, EJ Bennett, CR Braun, XY Zhang, SB McMahon, SP Gygi, ... Molecular and cellular biology 33 (8), 1487-1502, 2013 | 71 | 2013 |
| An HDAC3-PROX1 corepressor module acts on HNF4α to control hepatic triglycerides SM Armour, JR Remsberg, M Damle, S Sidoli, WY Ho, Z Li, BA Garcia, ... Nature communications 8 (1), 1-11, 2017 | 61 | 2017 |
| Carboxamide SIRT1 inhibitors block DBC1 binding via an acetylation-independent mechanism BP Hubbard, C Loh, AP Gomes, J Li, Q Lu, TLG Doyle, JS Disch, ... Cell cycle 12 (14), 2233-2240, 2013 | 27 | 2013 |
| Hepatic expression of GAA results in enhanced enzyme bioavailability in mice and non-human primates H Costa-Verdera, F Collaud, CR Riling, P Sellier, JML Nordin, ... Nature Communications 12 (1), 6393, 2021 | 14 | 2021 |
| SPK-8016: Preliminary results from a phase 1/2 clinical trial of gene therapy for hemophilia A SK Sullivan, JC Barrett, DA Drelich, MD Tarantino, A MacDougall, ... Haemophilia 27, 129-130, 2021 | 10 | 2021 |
| Preclinical assessment of an optimized AAV-FVIII vector in mice and non-human primates for the treatment of hemophilia A L Elkouby, SM Armour, R Toso, M DiPietro, RJ Davidson, GN Nguyen, ... Molecular Therapy-Methods & Clinical Development 24, 20-29, 2022 | 6 | 2022 |
| Xenohormesis based compositions and methods DA Sinclair, JA Baur, SM Armour US Patent App. 12/087,641, 2010 | 5 | 2010 |
| Methods and Compositions for Treatment Cell Proliferative Disorders DA Sinclair, JA Baur, SM Armour US Patent App. 12/087,631, 2009 | 5 | 2009 |
| Compositions and methods for increasing or enhancing transduction of gene therapy vectors and for removing or reducing immunoglobulins S Lacroix-Desmazes, F Mingozzi, J Dimitrov, C Leborgne, S Armour US Patent App. 17/050,911, 2021 | 3 | 2021 |
