Effect of vitamin C, hydrocortisone, and thiamine vs hydrocortisone alone on time alive and free of vasopressor support among patients with septic shock: the VITAMINS … T Fujii, N Luethi, PJ Young, DR Frei, GM Eastwood, CJ French, AM Deane, ... Jama 323 (5), 423-431, 2020 | 451 | 2020 |
Autoantibodies neutralizing type I IFNs are present in~ 4% of uninfected individuals over 70 years old and account for~ 20% of COVID-19 deaths P Bastard, A Gervais, T Le Voyer, J Rosain, Q Philippot, J Manry, ... Science immunology 6 (62), eabl4340, 2021 | 441 | 2021 |
Type I IFN immunoprofiling in COVID-19 patients S Trouillet-Assant, S Viel, A Gaymard, S Pons, JC Richard, M Perret, ... Journal of Allergy and Clinical Immunology 146 (1), 206-208. e2, 2020 | 298 | 2020 |
The risk of COVID-19 death is much greater and age dependent with type I IFN autoantibodies J Manry, P Bastard, A Gervais, T Le Voyer, J Rosain, Q Philippot, ... Proceedings of the National Academy of Sciences 119 (21), 2022 | 128 | 2022 |
Classic and nonclassic renin-angiotensin systems in the critically ill L Bitker, LM Burrell Critical care clinics 35 (2), 213-227, 2019 | 85 | 2019 |
COVID-19 symptoms at hospital admission vary with age and sex: results from the ISARIC prospective multinational observational study Infection 49 (5), 889-905, 2021 | 84 | 2021 |
Timing of initiation of renal-replacement therapy in acute kidney injury STARRT-AKI Investigators New England Journal of Medicine 383 (3), 240-251, 2020 | 83 | 2020 |
Restrictive fluid management versus usual care in acute kidney injury (REVERSE-AKI): a pilot randomized controlled feasibility trial ST Vaara, M Ostermann, L Bitker, A Schneider, E Poli, E Hoste, J Fierens, ... Intensive care medicine 47 (6), 665-673, 2021 | 57 | 2021 |
Change in cardiac output during Trendelenburg maneuver is a reliable predictor of fluid responsiveness in patients with acute respiratory distress syndrome in the prone … H Yonis, L Bitker, M Aublanc, S Perinel Ragey, Z Riad, F Lissonde, ... Critical care 21, 1-12, 2017 | 53 | 2017 |
Prevalence and risk factors of hypotension associated with preload-dependence during intermittent hemodialysis in critically ill patients L Bitker, F Bayle, H Yonis, F Gobert, V Leray, R Taponnier, S Debord, ... Critical Care 20, 1-11, 2016 | 49 | 2016 |
VITAMINS Trial Investigators: Effect of vitamin C, hydrocortisone, and thiamine vs hydrocortisone alone on time alive and free of vasopressor support among patients with septic … T Fujii, N Luethi, PJ Young, DR Frei, GM Eastwood, CJ French, AM Deane, ... JAMA 323 (5), 423-431, 2020 | 44 | 2020 |
Pharmacokinetic data support 6-hourly dosing of intravenous vitamin C to critically ill patients with septic shock EP Hudson, JTB Collie, T Fujii, N Luethi, AA Udy, S Doherty, G Eastwood, ... Critical care and resuscitation 21 (4), 236-242, 2019 | 36 | 2019 |
The value of open-source clinical science in pandemic response: lessons from ISARIC A Abbas, SA Abdukahil, NN Abdulkadir, R Abe, L Abel, L Absil, S Acharya, ... The Lancet infectious diseases 21 (12), 1623-1624, 2021 | 33 | 2021 |
Impact on disease mortality of clinical, biological, and virological characteristics at hospital admission and overtime in COVID‐19 patients Y Yazdanpanah, French COVID Cohort Investigators and Study Group, ... Journal of Medical Virology 93 (4), 2149-2159, 2021 | 33 | 2021 |
Feasibility and safety of ultra-low tidal volume ventilation without extracorporeal circulation in moderately severe and severe ARDS patients JC Richard, S Marque, A Gros, M Muller, G Prat, G Beduneau, JP Quenot, ... Intensive Care Medicine 45, 1590-1598, 2019 | 31 | 2019 |
Hemodynamic effects of extended prone position sessions in ARDS M Ruste, L Bitker, H Yonis, Z Riad, A Louf-Durier, F Lissonde, ... Annals of Intensive Care 8, 1-10, 2018 | 30 | 2018 |
Presence of kidney disease as an outcome predictor in patients with pulmonary arterial hypertension L Bitker, F Sens, C Payet, S Turquier, A Duclos, V Cottin, L Juillard American journal of nephrology 47 (2), 134-143, 2018 | 30 | 2018 |
Imaging the acute respiratory distress syndrome: past, present and future L Bitker, D Talmor, JC Richard Intensive Care Medicine 48 (8), 995-1008, 2022 | 28 | 2022 |
A pilot, double-blind, randomized, controlled trial of high-dose intravenous vitamin C for vasoplegia after cardiac surgery F Yanase, L Bitker, L Hessels, E Osawa, T Naorungroj, SL Cutuli, ... Journal of cardiothoracic and vascular anesthesia 34 (2), 409-416, 2020 | 28 | 2020 |
Protracted viral shedding and viral load are associated with ICU mortality in Covid-19 patients with acute respiratory failure L Bitker, F Dhelft, L Chauvelot, E Frobert, L Folliet, M Mezidi, ... Annals of Intensive Care 10, 1-9, 2020 | 24 | 2020 |