Mark R. Spaller
Mark R. Spaller
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TitleCited byYear
Dual role of the exocyst in AMPA receptor targeting and insertion into the postsynaptic membrane
NZ Gerges, DS Backos, CN Rupasinghe, MR Spaller, JA Esteban
The EMBO journal 25 (8), 1623-1634, 2006
Monomeric yeast frataxin is an iron-binding protein
JD Cook, KZ Bencze, AD Jankovic, AK Crater, CN Busch, PB Bradley, ...
Biochemistry 45 (25), 7767-7777, 2006
Impairment of TrkB-PSD-95 signaling in Angelman syndrome
C Cao, MS Rioult-Pedotti, P Migani, CJ Yu, R Tiwari, K Parang, ...
PLoS biology 11 (2), 2013
Enantio-and diastereoselectivity in the intramolecular cyclopropanation of secondary allylic diazoacetates
SF Martin, MR Spaller, S Liras, B Hartmann
Journal of the American Chemical Society 116 (10), 4493-4494, 1994
Highly selective enantiomer differentiation in intramolecular cyclopropanation reactions of racemic secondary allylic diazoacetates.
MP Doyle, AB Dyatkin, AV Kalinin, DA Ruppar, SF Martin, MR Spaller, ...
Journal of the American Chemical Society 117 (44), 11021-11022, 1995
A thermodynamic ligand binding study of the third PDZ domain (PDZ3) from the mammalian neuronal protein PSD-95
D Saro, T Li, C Rupasinghe, A Paredes, N Caspers, MR Spaller
Biochemistry 46 (21), 6340-6352, 2007
Targeting specific PDZ domains of PSD-95: Structural basis for enhanced affinity and enzymatic stability of a cyclic peptide
A Piserchio, GD Salinas, T Li, J Marshall, MR Spaller, DF Mierke
Chemistry & biology 11 (4), 469-473, 2004
Synthetic strategies in combinatorial chemistry
MR Spaller, MT Burger, M Fardis, PA Bartlett
Current opinion in chemical biology 1 (1), 47-53, 1997
Conformational constraint in protein ligand design and the inconsistency of binding entropy
DG Udugamasooriya, MR Spaller
Biopolymers: Original Research on Biomolecules 89 (8), 653-667, 2008
PTEN recruitment controls synaptic and cognitive function in Alzheimer's models
S Knafo, C Sánchez-Puelles, E Palomer, I Delgado, JE Draffin, J Mingo, ...
Nature neuroscience 19 (3), 443, 2016
Thermodynamic profiling of conformationally constrained cyclic ligands for the PDZ domain
T Li, D Saro, MR Spaller
Bioorganic & medicinal chemistry letters 14 (6), 1385-1388, 2004
Combinatorial Synthetic Design. Solution and Polymer-Supported Synthesis of Heterocycles via Intramolecular Aza Diels− Alder and Imino Alcohol Cyclizations
MR Spaller, WT Thielemann, PE Brennan, PA Bartlett
Journal of combinatorial chemistry 4 (5), 516-522, 2002
Targeting GIPC/synectin in pancreatic cancer inhibits tumor growth
MH Muders, PK Vohra, SK Dutta, E Wang, Y Ikeda, L Wang, ...
Clinical Cancer Research 15 (12), 4095-4103, 2009
Selection of peptides that target the aminoacyl-tRNA site of bacterial 16S ribosomal RNA
M Li, AC E. Duc, E Klosi, S Pattabiraman, MR Spaller, CS Chow
Biochemistry 48 (35), 8299-8311, 2009
Expanding the synthetic method and structural diversity potential for the intramolecular aza Diels− Alder cyclization
J Muhuhi, MR Spaller
The Journal of organic chemistry 71 (15), 5515-5526, 2006
Inhibition of N-methyl-D-aspartate-induced retinal neuronal death by polyarginine peptides is linked to the attenuation of stress-induced hyperpolarization of the inner …
J Marshall, KY Wong, CN Rupasinghe, R Tiwari, X Zhao, ED Berberoglu, ...
Journal of Biological Chemistry 290 (36), 22030-22048, 2015
A cyclic peptide targeted against PSD-95 blocks central sensitization and attenuates thermal hyperalgesia
BW LeBlanc, M Iwata, AP Mallon, CN Rupasinghe, DJ Goebel, J Marshall, ...
Neuroscience 167 (2), 490-500, 2010
Expression and Site-Directed Mutagenesis of the Phosphatidylcholine-Preferring Phospholipase C of Bacillus cereus:  Probing the Role of the Active Site Glu146
SF Martin, MR Spaller, PJ Hergenrother
Biochemistry 35 (39), 12970-12977, 1996
T7 phage display as a method of peptide ligand discovery for PDZ domain proteins
SC Sharma, A Memic, CN Rupasinghe, ACE Duc, MR Spaller
Peptide Science: Original Research on Biomolecules 92 (3), 183-193, 2009
Bridged peptide macrocycles as ligands for PDZ domain proteins
G Udugamasooriya, D Saro, MR Spaller
Organic letters 7 (7), 1203-1206, 2005
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