| A general reaction mechanism for carbapenem hydrolysis by mononuclear and binuclear metallo-β-lactamases MN Lisa, AR Palacios, M Aitha, MM González, DM Moreno, MW Crowder, ... Nature communications 8 (1), 538, 2017 | 125 | 2017 |
| The metallo-β-lactamase GOB is a mono-Zn (II) enzyme with a novel active site J Moran-Barrio, JM Gonzalez, MN Lisa, AL Costello, M Dal Peraro, ... Journal of Biological Chemistry 282 (25), 18286-18293, 2007 | 97 | 2007 |
| PknG senses amino acid availability to control metabolism and virulence of Mycobacterium tuberculosis B Rieck, G Degiacomi, M Zimmermann, A Cascioferro, F Boldrin, ... PLoS pathogens 13 (5), e1006399, 2017 | 89 | 2017 |
| Bidirectional allosteric communication between the ATP-binding site and the regulatory PIF pocket in PDK1 protein kinase JO Schulze, G Saladino, K Busschots, S Neimanis, E Süß, D Odadzic, ... Cell chemical biology 23 (10), 1193-1205, 2016 | 73 | 2016 |
| Molecular Basis of the Activity and the Regulation of the Eukaryotic-like S/T Protein Kinase PknG from Mycobacterium tuberculosis MN Lisa, M Gil, G André-Leroux, N Barilone, R Durán, RM Biondi, ... Structure 23 (6), 1039-1048, 2015 | 48 | 2015 |
| Crystal structure of the metallo-β-lactamase GOB in the periplasmic dizinc form reveals an unusual metal site J Morán-Barrio, MN Lisa, N Larrieux, SI Drusin, AM Viale, DM Moreno, ... Antimicrobial agents and chemotherapy 60 (10), 6013-6022, 2016 | 45 | 2016 |
| Catalytic Role of the Metal Ion in the Metallo-β-lactamase GOB 2 MN Lisa, L Hemmingsen, AJ Vila Journal of biological chemistry 285 (7), 4570-4577, 2010 | 42 | 2010 |
| SIMBAD: a sequence-independent molecular-replacement pipeline AJ Simpkin, F Simkovic, JMH Thomas, M Savko, A Lebedev, V Uski, ... Acta Crystallographica Section D: Structural Biology 74 (7), 595-605, 2018 | 32 | 2018 |
| Structural insights into the functional versatility of an FHA domain protein in mycobacterial signaling T Wagner, G André-Leroux, V Hindie, N Barilone, MN Lisa, S Hoos, ... Science Signaling 12 (580), eaav9504, 2019 | 23 | 2019 |
| New substrates and interactors of the mycobacterial Serine/Threonine protein kinase PknG identified by a tailored interactomic approach M Gil, A Lima, B Rivera, J Rossello, E Urdániz, A Cascioferro, F Carrión, ... Journal of proteomics 192, 321-333, 2019 | 21 | 2019 |
| Double autoinhibition mechanism of signal transduction ATPases with numerous domains (STAND) with a tetratricopeptide repeat sensor MN Lisa, V Cvirkaite-Krupovic, E Richet, G André-Leroux, PM Alzari, ... Nucleic acids research 47 (7), 3795-3810, 2019 | 10 | 2019 |
| Arabidopsis thaliana Hcc1 is a Sco‐like metallochaperone for CuA assembly in Cytochrome c Oxidase ME Llases, MN Lisa, MN Morgada, E Giannini, PM Alzari, AJ Vila The FEBS Journal 287 (4), 749-762, 2020 | 8 | 2020 |
| Probing the role of Met221 in the unusual metallo-β-lactamase GOB-18 MN Lisa, J Morán-Barrio, MF Guindón, AJ Vila Inorganic chemistry 51 (22), 12419-12425, 2012 | 8 | 2012 |
| Novel high-performance purification protocol of recombinant CNBP suitable for biochemical and biophysical characterization E Challier, MN Lisa, BB Nerli, NB Calcaterra, P Armas Protein Expression and Purification 93, 23-31, 2014 | 7 | 2014 |
| In Vivo Impact of Met221 Substitution in GOB Metallo-β-Lactamase J Morán-Barrio, MN Lisa, AJ Vila Antimicrobial agents and chemotherapy 56 (4), 1769-1773, 2012 | 7 | 2012 |
| Proteome remodeling in the Mycobacterium tuberculosis PknG knockout: Molecular evidence for the role of this kinase in cell envelope biogenesis and hypoxia response A Lima, A Leyva, B Rivera, MM Portela, M Gil, A Cascioferro, MN Lisa, ... Journal of Proteomics 244, 104276, 2021 | 6 | 2021 |
| The distinctive roles played by the superoxide dismutases of the extremophile Acinetobactersp. Ver3 BA Steimbrüch, MG Sartorio, N Cortez, D Albanesi, MN Lisa, GD Repizo Scientific Reports 12 (1), 4321, 2022 | 4 | 2022 |
| 3D architecture and structural flexibility revealed in the subfamily of large glutamate dehydrogenases by a mycobacterial enzyme M Lázaro, R Melero, C Huet, JP López-Alonso, S Delgado, A Dodu, ... Communications Biology 4 (1), 684, 2021 | 4 | 2021 |
| Structure-based virtual screening to get new scaffold inhibitors of the Ser/Thr protein kinase PknB from mycobacterium tuberculosis A Coluccia, G La Regina, N Barilone, MN Lisa, A Brancale, ... Letters in Drug Design & Discovery 13 (10), 1012-1018, 2016 | 4 | 2016 |
| Unexpected electron spin density on the axial methionine ligand in Cu A suggests its involvement in electron pathways MN Morgada, ME Llases, E Giannini, MA Castro, PM Alzari, DH Murgida, ... Chemical communications 56 (8), 1223-1226, 2020 | 3 | 2020 |
Alejandro J. VilaIBR (Instituto de Biologia Molecular y Celular de Rosario), CONICET-UNRVerified email at ibr-conicet.gov.ar
