| Neurosteroid dehydroepiandrosterone interacts with nerve growth factor (NGF) receptors, preventing neuronal apoptosis I Lazaridis, I Charalampopoulos, VI Alexaki, N Avlonitis, I Pediaditakis, ... PLoS biology 9 (4), e1001051, 2011 | 143 | 2011 |
| Modeling alpha-synuclein pathology in a human brain-chip to assess blood-brain barrier disruption I Pediaditakis, KR Kodella, DV Manatakis, CY Le, CD Hinojosa, ... Nature communications 12 (1), 5907, 2021 | 109 | 2021 |
| Genetic dissection of neurotrophin signaling through the p75 neurotrophin receptor I Charalampopoulos, A Vicario, I Pediaditakis, A Gravanis, A Simi, ... Cell reports 2 (6), 1563-1570, 2012 | 70 | 2012 |
| Differential effects of dehydroepiandrosterone and testosterone in prostate and colon cancer cell apoptosis: the role of nerve growth factor (NGF) receptors V Anagnostopoulou, I Pediaditakis, S Alkahtani, SA Alarifi, EM Schmidt, ... Endocrinology 154 (7), 2446-2456, 2013 | 60 | 2013 |
| APRIL binding to BCMA activates a JNK2–FOXO3–GADD45 pathway and induces a G2/M cell growth arrest in liver cells G Notas, VI Alexaki, M Kampa, V Pelekanou, I Charalampopoulos, ... The Journal of Immunology 189 (10), 4748-4758, 2012 | 54 | 2012 |
| Antagonizing effects of membrane-acting androgens on the eicosanoid receptor OXER1 in prostate cancer K Kalyvianaki, V Gebhart, N Peroulis, C Panagiotopoulou, F Kiagiadaki, ... Scientific reports 7 (1), 44418, 2017 | 49 | 2017 |
| Dehydroepiandrosterone: an ancestral ligand of neurotrophin receptors I Pediaditakis, I Iliopoulos, I Theologidis, N Delivanoglou, AN Margioris, ... Endocrinology 156 (1), 16-23, 2015 | 42 | 2015 |
| Selective and differential interactions of BNN27, a novel C17-spiroepoxy steroid derivative, with TrkA receptors, regulating neuronal survival and differentiation I Pediaditakis, P Efstathopoulos, KC Prousis, M Zervou, JC Arévalo, ... Neuropharmacology 111, 266-282, 2016 | 39 | 2016 |
| The neurosteroid dehydroepiandrosterone (DHEA) protects the retina from AMPA-induced excitotoxicity: NGF TrkA receptor involvement D Kokona, I Charalampopoulos, I Pediaditakis, A Gravanis, K Thermos Neuropharmacology 62 (5-6), 2106-2117, 2012 | 31 | 2012 |
| BNN27, a 17-spiroepoxy steroid derivative, interacts with and activates p75 neurotrophin receptor, rescuing cerebellar granule neurons from apoptosis I Pediaditakis, A Kourgiantaki, KC Prousis, C Potamitis, KP Xanthopoulos, ... Frontiers in Pharmacology 7, 235947, 2016 | 29 | 2016 |
| Pasireotide (SOM230) protects the retina in animal models of ischemia induced retinopathies D Kokona, N Mastrodimou, I Pediaditakis, I Charalampopoulos, ... Experimental eye research 103, 90-98, 2012 | 25 | 2012 |
| ERα17p, an ERα P295‐T311 fragment, modifies the migration of breast cancer cells, through actin cytoskeleton rearrangements M Kampa, V Pelekanou, D Gallo, G Notas, M Troullinaki, I Pediaditakis, ... Journal of cellular biochemistry 112 (12), 3786-3796, 2011 | 25 | 2011 |
| BNN-20, a synthetic microneurotrophin, strongly protects dopaminergic neurons in the “weaver” mouse, a genetic model of dopamine-denervation, acting through the TrkB … K Botsakis, T Mourtzi, V Panagiotakopoulou, M Vreka, GT Stathopoulos, ... Neuropharmacology 121, 140-157, 2017 | 24 | 2017 |
| A microengineered Brain-Chip to model neuroinflammation in humans I Pediaditakis, KR Kodella, DV Manatakis, CY Le, S Barthakur, A Sorets, ... Iscience 25 (8), 2022 | 16 | 2022 |
| Synthetic microneurotrophins in therapeutics of neurodegeneration. A Gravanis, I Pediaditakis, I Charalampopoulos Oncotarget, 2017 | 8 | 2017 |
| Modeling Alpha-synuclein pathology in a human brain-chip to assess blood-brain barrier disruption in Parkinson’s disease I Pediaditakis, KR Kodella, DV Manatakis, CD Hinojosa, ES Manolakos, ... BioRxiv, 2020.07. 22.207340, 2020 | 7 | 2020 |
| The future of Parkinson’s disease research: a new paradigm of human-specific investigation is necessary… and possible M Cassotta, H Geerts, L Harbom, TF Outeiro, I Pediaditakis, O Reiner, ... ALTEX: Alternatives to Animal Experimentation, 2022 | 6 | 2022 |
| Flagship Pioneering I Pediaditakis United States, 0 | 2 | |
| From evolution to pharmacology: developing agonists of neurotrophin receptors A Gravanis, I Pediaditakis, P Efstathopoulos, A Kourgiantaki, ... Febs Journal 280, 345-345, 2013 | 1 | 2013 |
| Effects of space travel on human brain cells CD Hinojosa, J Sliz, I Pediaditakis, S Barthakur US Patent 11,697,792, 2023 | | 2023 |
Ioannis CharalampopoulosProfessor, Medical School, University of Crete & Researcher, Institute of MolecularVerified email at uoc.gr
